Hypoxic Non-replicating Persistent Mycobacterium tuberculosis Develops Thickened Outer Layer That Helps in Restricting Rifampicin Entry

by Kishor Jakkala, Parthasarathi Ajitkumar
Published 2019-10-01

MtFtsX a predicted membrane domain of ABC transporter complex MtFtsEX of Mycobacterium tuberculosis interacts with the cell division protein MtFtsZ

by Mushtaq Ahmad Mir, Ramanujam Srinivasan, Parthasarathi Ajitkumar
Published 2019-01-01

A Minor Subpopulation of Mycobacteria Inherently Produces High Levels of Reactive Oxygen Species That Generate Antibiotic Resisters at High Frequency From Itself and Enhance Resist...

by Rashmi Ravindran Nair, Deepti Sharan, Parthasarathi Ajitkumar
Published 2019-08-01

Mycobacterial Populations Partly Change the Proportions of the Cells Undergoing Asymmetric/Symmetric Divisions in Response to Glycerol Levels in Growth Medium

by Atul Pradhan, Nagaraja Mukkayyan, Kishor Jakkala, Parthasarathi Ajitkumar
Published 2021-05-01

Mycobacterium tuberculosis Cells Surviving in the Continued Presence of Bactericidal Concentrations of Rifampicin in vitro Develop Negatively Charged Thickened Capsular Outer Layer...

by Jees Sebastian, Rashmi Ravindran Nair, Sharmada Swaminath, Parthasarathi Ajitkumar
Published 2020-12-01

Mycobacterium smegmatis strains genetically resistant to moxifloxacin emerge de novo from the moxifloxacin-surviving population containing high levels of superoxide, H2O2, hydroxyl...

by Avraneel Paul, Rashmi Ravindran Nair, Kishor Jakkala, Parthasarathi Ajitkumar
Published 2022-01-01

Deletion of rifampicin-inactivating mono-ADP-ribosyl transferase gene of Mycobacterium smegmatis globally altered gene expression profile that favoured increase in ROS levels and t...

by Sharmada Swaminath, Atul Pradhan, Rashmi Ravindran Nair, Parthasarathi Ajitkumar
Published 2022-01-01

Percoll discontinuous density gradient centrifugation method for the fractionation of the subpopulations of Mycobacterium smegmatis and Mycobacterium tuberculosis from in vitro cul...

by Srinivasan Vijay, Rashmi Ravindran Nair, Deepti Sharan, Kishor Jakkala, Parthasarathi Ajitkumar
Published 2023-12-01

Growth and division mechanisms by which genetic resisters emerge from the rifampicin-surviving population of differentially antibiotic-susceptible mycobacterial subpopulations

by Kishor Jakkala, Avraneel Paul, Rashmi Ravindran Nair, Sharmada Swaminath, Atul Pradhan, Parthasarathi Ajitkumar
Published 2022-01-01

The H2O2 inherently released by the mycobacterial minor subpopulation enhances the survival of the major kin subpopulation against rifampicin

by Rashmi Ravindran Nair, Deepti Sharan, Vijay Srinivasan, Nagaraja Mukkayyan, Kishor Jakkala, Parthasarathi Ajitkumar
Published 2022-01-01

Unique Mode of Cell Division by the Mycobacterial Genetic Resister Clones Emerging <italic toggle="yes">De Novo</italic> from the Antibiotic-Surviving Population

by Kishor Jakkala, Avraneel Paul, Atul Pradhan, Rashmi Ravindran Nair, Deepti Sharan, Sharmada Swaminath, Parthasarathi Ajitkumar
Published 2020-12-01

NDK Interacts with FtsZ and Converts GDP to GTP to Trigger FtsZ Polymerisation--A Novel Role for NDK.

by Saurabh Mishra, Kishor Jakkala, Ramanujam Srinivasan, Muthu Arumugam, Raghavendra Ranjeri, Prabuddha Gupta, Haryadi Rajeswari, Parthasarathi Ajitkumar
Published 2015-01-01

Complete identity and expression of StfZ, the cis-antisense RNA to the mRNA of the cell division gene ftsZ, in Escherichia coli

by Deepak Anand, Deepak Anand, Kishor Jakkala, Kishor Jakkala, Rashmi Ravindran Nair, Rashmi Ravindran Nair, Deepti Sharan, Deepti Sharan, Atul Pradhan, Atul Pradhan, Nagaraja Mukkayyan, Nagaraja Mukkayyan, Parthasarathi Ajitkumar
Published 2022-10-01

Redox-dependent condensation of the mycobacterial nucleoid by WhiB4

by Manbeena Chawla, Saurabh Mishra, Kushi Anand, Pankti Parikh, Mansi Mehta, Manika Vij, Taru Verma, Parul Singh, Kishor Jakkala, H.N. Verma, Parthasarathi AjitKumar, Munia Ganguli, Aswin Sai Narain Seshasayee, Amit Singh
Published 2018-10-01