<i>MOSR</i> and <i>NDH</i>A Genes Comprising G-Quadruplex as Promising Therapeutic Targets against <i>Mycobacterium tuberculosis</i>: Molecular Recognition by Mitoxantrone Suppress...

by Arpita Dey, Kushi Anand, Amit Singh, Ramasare Prasad, Ritu Barthwal
Published 2023-04-01

Binding-induced thermal stabilization of mosR and ndhA G-quadruplex comprising genes by emodin leads to downregulation and growth inhibition in Mtb: Potential as anti-tuberculosis...

by Arpita Dey, Kushi Anand, Amit Singh, Ramasare Prasad, Ritu Barthwal
Published 2023-12-01

Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis

by Saurabh Mishra, Prashant Shukla, Ashima Bhaskar, Kushi Anand, Priyanka Baloni, Rajiv Kumar Jha, Abhilash Mohan, Raju S Rajmani, Valakunja Nagaraja, Nagasuma Chandra, Amit Singh
Published 2017-05-01

Mycobacterium tuberculosis requires SufT for Fe-S cluster maturation, metabolism, and survival in vivo.

by Ashutosh Tripathi, Kushi Anand, Mayashree Das, Ruchika Annie O'Niel, Sabarinath P S, Chandrani Thakur, Raghunatha Reddy R L, Raju S Rajmani, Nagasuma Chandra, Sunil Laxman, Amit Singh
Published 2022-04-01

Redox-dependent condensation of the mycobacterial nucleoid by WhiB4

by Manbeena Chawla, Saurabh Mishra, Kushi Anand, Pankti Parikh, Mansi Mehta, Manika Vij, Taru Verma, Parul Singh, Kishor Jakkala, H.N. Verma, Parthasarathi AjitKumar, Munia Ganguli, Aswin Sai Narain Seshasayee, Amit Singh
Published 2018-10-01

Mycobacterium tuberculosis SufR responds to nitric oxide via its 4Fe–4S cluster and regulates Fe–S cluster biogenesis for persistence in mice

by Kushi Anand, Ashutosh Tripathi, Kaustubh Shukla, Nitish Malhotra, Anil Kumar Jamithireddy, Rajiv Kumar Jha, Susmit Narayan Chaudhury, Raju S. Rajmani, Arati Ramesh, Valakunja Nagaraja, Balasubramanian Gopal, Ganesh Nagaraju, Aswin Sai Narain Seshayee, Amit Singh
Published 2021-10-01