Nonpeptidic Z360-Analogs Tagged with Trivalent Radiometals as Anti-CCK₂R Cancer Theranostic Agents: A Preclinical Study

by Berthold A. Nock, Panagiotis Kanellopoulos, Oleg G. Chepurny, Maritina Rouchota, George Loudos, George G. Holz, Eric P. Krenning, Theodosia Maina
Published 2022-03-01

PI3 kinases p110α and PI3K-C2β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets

by Jelena Kolic, Jocelyn E. Manning Fox, Oleg G. Chepurny, Aliya F. Spigelman, Mourad Ferdaoussi, Frank Schwede, George G. Holz, Patrick E. MacDonald
Published 2016-07-01

A peptide triple agonist of GLP-1, neuropeptide Y1, and neuropeptide Y2 receptors promotes glycemic control and weight loss

by Kylie S. Chichura, Clinton T. Elfers, Therese S. Salameh, Varun Kamat, Oleg G. Chepurny, Aelish McGivney, Brandon T. Milliken, George G. Holz, Sarah V. Applebey, Matthew R. Hayes, Ian R. Sweet, Christian L. Roth, Robert P. Doyle
Published 2023-06-01

Corrination of a GLP-1 Receptor Agonist for Glycemic Control without Emesis

by Tito Borner, Jayme L. Workinger, Ian C. Tinsley, Samantha M. Fortin, Lauren M. Stein, Oleg G. Chepurny, George G. Holz, Aleksandra J. Wierzba, Dorota Gryko, Ebba Nexø, Evan D. Shaulson, Ankur Bamezai, Valentina A. Rodriguez Da Silva, Bart C. De Jonghe, Matthew R. Hayes, Robert P. Doyle
Published 2020-06-01