Editorial: Bench to bedside: translating pre-clinical research into clinical trials for childhood brain tumors

by Raelene Endersby, Raelene Endersby, Brandon J. Wainwright, Nicholas G. Gottardo, Nicholas G. Gottardo, Nicholas G. Gottardo
Published 2023-08-01

Conventional Therapies Deplete Brain-Infiltrating Adaptive Immune Cells in a Mouse Model of Group 3 Medulloblastoma Implicating Myeloid Cells as Favorable Immunotherapy Targets

by Zahra Abbas, Zahra Abbas, Courtney George, Courtney George, Mathew Ancliffe, Mathew Ancliffe, Meegan Howlett, Meegan Howlett, Anya C. Jones, Anya C. Jones, Mani Kuchibhotla, Robert J. Wechsler-Reya, Nicholas G. Gottardo, Nicholas G. Gottardo, Nicholas G. Gottardo, Raelene Endersby, Raelene Endersby
Published 2022-03-01

Efficacy of acute myeloid leukemia therapy without stem-cell transplantation in a child with blastic plasmacytoid dendritic cell neoplasm

by Jordan R. Hansford, Rishi S. Kotecha, Gareth Jevon, Catherine H. Cole, Nicholas G. Gottardo
Published 2013-03-01

Long-term outcomes of symptomatic optic pathway glioma: 32-year experience at a single Western Australian tertiary pediatric oncology center

by Revathi Rajagopal, Mumtaz Khan, Robert Lethbridge, Gabriel Lee, Sharon Lee, Jason Dyke, Vicki Fabian, Alycea McGrath, Mandy Taylor, Peter Jacoby, Raelene Endersby, Sumanth Nagabushan, Sumanth Nagabushan, Nicholas G. Gottardo, Nicholas G. Gottardo
Published 2023-07-01

Integrated analysis of miRNA and mRNA expression in childhood medulloblastoma compared with neural stem cells.

by Laura A Genovesi, Kim W Carter, Nicholas G Gottardo, Keith M Giles, Peter B Dallas
Published 2011-01-01

Gene expression analyses of the spatio-temporal relationships of human medulloblastoma subgroups during early human neurogenesis.

by Cornelia M Hooper, Susan M Hawes, Ursula R Kees, Nicholas G Gottardo, Peter B Dallas
Published 2014-01-01

A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors

by Raelene Endersby, Jacqueline Whitehouse, Hilary Hii, Sameer A. Greenall, Terrance G. Johns, Nicholas G. Gottardo
Published 2018-05-01

Prognostic significance of molecular subgroups in survival outcome for children with medulloblastoma in Malaysia

by Revathi Rajagopal, Ay Jiuan Teng, Vida Jawin, Oy Leng Wong, Hakimah Mahsin, Nor Haizura Abd Rani, Tsiao Yi Yap, Kogilavani Gunasagaran, Asohan Thevarajah, Seoh Leng Yeoh, Gek Bee Ong, Hany Ariffin, David Jones, Eric Bouffet, Nicholas G. Gottardo, Nicholas G. Gottardo
Published 2023-10-01

Veliparib Is an Effective Radiosensitizing Agent in a Preclinical Model of Medulloblastoma

by Jessica Buck, Jessica Buck, Patrick J. C. Dyer, Hilary Hii, Brooke Carline, Mani Kuchibhotla, Jacob Byrne, Meegan Howlett, Meegan Howlett, Jacqueline Whitehouse, Jacqueline Whitehouse, Martin A. Ebert, Martin A. Ebert, Kerrie L. McDonald, Nicholas G. Gottardo, Nicholas G. Gottardo, Raelene Endersby, Raelene Endersby
Published 2021-04-01

Malignant Melanoma in Children and Adolescents Treated in Pediatric Oncology Centers: An Australian and New Zealand Children’s Oncology Group (ANZCHOG) Study

by Anne L. Ryan, Charlotte Burns, Aditya K. Gupta, Ruvishani Samarasekera, David S. Ziegler, Maria L. Kirby, Frank Alvaro, Peter Downie, Peter Downie, Stephen J. Laughton, Siobhan Cross, Timothy Hassall, Geoff B. McCowage, Jordan R. Hansford, Jordan R. Hansford, Rishi S. Kotecha, Rishi S. Kotecha, Rishi S. Kotecha, Nicholas G. Gottardo, Nicholas G. Gottardo
Published 2021-04-01

Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated Complication

by Helen C. Atkinson, Julie A. Marsh, Shoshana R. Rath, Rishi S. Kotecha, Hazel Gough, Mandy Taylor, Thomas Walwyn, Nicholas G. Gottardo, Catherine H. Cole, Catherine S. Choong
Published 2015-01-01

Activation of ERBB4 in Glioblastoma Can Contribute to Increased Tumorigenicity and Influence Therapeutic Response

by Jacqueline F. Donoghue, Lauren T. Kerr, Naomi W. Alexander, Sameer A. Greenall, Anthony B. Longano, Nicholas G. Gottardo, Rong Wang, Viviane Tabar, Timothy E. Adams, Paul S. Mischel, Terrance G. Johns
Published 2018-07-01

Exercise training improves vascular function and secondary health measures in survivors of pediatric oncology related cerebral insult.

by Treya M Long, Shoshana R Rath, Karen E Wallman, Erin K Howie, Leon M Straker, Andrew Bullock, Thomas S Walwyn, Nicholas G Gottardo, Catherine H Cole, Catherine S Choong, Louise H Naylor
Published 2018-01-01

Assessment of Cannabidiol and Δ9-Tetrahydrocannabiol in Mouse Models of Medulloblastoma and Ependymoma

by Clara Andradas, Jacob Byrne, Mani Kuchibhotla, Mathew Ancliffe, Anya C. Jones, Brooke Carline, Hilary Hii, Alexandra Truong, Lisa C. D. Storer, Timothy A. Ritzmann, Richard G. Grundy, Nicholas G. Gottardo, Raelene Endersby
Published 2021-01-01

In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma

by Jacqueline P. Whitehouse, Jacqueline P. Whitehouse, Hilary Hii, Chelsea Mayoh, Chelsea Mayoh, Marie Wong, Marie Wong, Pamela Ajuyah, Paulette Barahona, Louise Cui, Hetal Dholaria, Hetal Dholaria, Hetal Dholaria, Christine L. White, Christine L. White, Christine L. White, Molly K. Buntine, Molly K. Buntine, Jacob Byrne, Keteryne Rodrigues da Silva, Keteryne Rodrigues da Silva, Meegan Howlett, Meegan Howlett, Emily J. Girard, Emily J. Girard, Maria Tsoli, Maria Tsoli, David S. Ziegler, David S. Ziegler, David S. Ziegler, Jason M. Dyke, Jason M. Dyke, Sharon Lee, Paul G. Ekert, Paul G. Ekert, Paul G. Ekert, Paul G. Ekert, Paul G. Ekert, Mark J. Cowley, Mark J. Cowley, Nicholas G. Gottardo, Nicholas G. Gottardo, Nicholas G. Gottardo, Raelene Endersby, Raelene Endersby
Published 2023-03-01

Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma

by Laura A. Genovesi, Amanda Millar, Elissa Tolson, Matthew Singleton, Emily Hassall, Marija Kojic, Caterina Brighi, Emily Girard, Clara Andradas, Mani Kuchibhotla, Dharmesh D. Bhuva, Raelene Endersby, Nicholas G. Gottardo, Anne Bernard, Christelle Adolphe, James M. Olson, Michael D. Taylor, Melissa J. Davis, Brandon J. Wainwright
Published 2021-06-01

A Novel Orthotopic Patient-Derived Xenograft Model of Radiation-Induced Glioma Following Medulloblastoma

by Jacqueline P. Whitehouse, Meegan Howlett, Hilary Hii, Chelsea Mayoh, Marie Wong, Paulette Barahona, Pamela Ajuyah, Christine L. White, Molly K. Buntine, Jason M. Dyke, Sharon Lee, Santosh Valvi, Jason Stanley, Clara Andradas, Brooke Carline, Mani Kuchibhotla, Paul G. Ekert, Mark J. Cowley, Nicholas G. Gottardo, Raelene Endersby
Published 2020-10-01

BRAF-mediated brain tumors in adults and children: A review and the Australian and New Zealand experience

by Sarah M. Trinder, Campbell McKay, Phoebe Power, Phoebe Power, Monique Topp, Bosco Chan, Santosh Valvi, Geoffrey McCowage, Geoffrey McCowage, Dinisha Govender, Maria Kirby, David S. Ziegler, David S. Ziegler, David S. Ziegler, Neevika Manoharan, Neevika Manoharan, Tim Hassall, Stewart Kellie, John Heath, Frank Alvaro, Paul Wood, Stephen Laughton, Karen Tsui, Andrew Dodgshun, David D. Eisenstat, David D. Eisenstat, David D. Eisenstat, Raelene Endersby, Raelene Endersby, Stephen J. Luen, Eng-Siew Koh, Eng-Siew Koh, Eng-Siew Koh, Hao-Wen Sim, Hao-Wen Sim, Hao-Wen Sim, Hao-Wen Sim, Benjamin Kong, Benjamin Kong, Nicholas G. Gottardo, Nicholas G. Gottardo, James R. Whittle, Dong-Anh Khuong-Quang, Jordan R. Hansford, Jordan R. Hansford, Jordan R. Hansford
Published 2023-04-01

Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG Registry

by Hunter C. Gits, Maia Anderson, Stefanie Stallard, Drew Pratt, Becky Zon, Christopher Howell, Chandan Kumar-Sinha, Pankaj Vats, Katayoon Kasaian, Daniel Polan, Martha Matuszak, Daniel E. Spratt, Marcia Leonard, Tingting Qin, Lili Zhao, James Leach, Brooklyn Chaney, Nancy Yanez Escorza, Jacob Hendershot, Blaise Jones, Christine Fuller, Sarah Leary, Ute Bartels, Eric Bouffet, Torunn I. Yock, Patricia Robertson, Rajen Mody, Sriram Venneti, Arul M. Chinnaiyan, Maryam Fouladi, Nicholas G. Gottardo, Carl Koschmann
Published 2018-07-01

A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer

by Chelsea Mayoh, Andrew J. Gifford, Rachael Terry, Loretta M. S. Lau, Marie Wong, Padmashree Rao, Tyler Shai-Hee, Federica Saletta, Dong-Anh Khuong-Quang, Vicky Qin, Marion K. Mateos, Deborah Meyran, Katherine E. Miller, Aysen Yuksel, Emily V. A. Mould, Rachel Bowen-James, Dinisha Govender, Akanksha Senapati, Nataliya Zhukova, Natacha Omer, Hetal Dholaria, Frank Alvaro, Heather Tapp, Yonatan Diamond, Luciano Dalla Pozza, Andrew S. Moore, Wayne Nicholls, Nicholas G. Gottardo, Geoffrey McCowage, Jordan R. Hansford, Seong-Lin Khaw, Paul J. Wood, Daniel Catchpoole, Catherine E. Cottrell, Elaine R. Mardis, Glenn M. Marshall, Vanessa Tyrrell, Michelle Haber, David S. Ziegler, Orazio Vittorio, Joseph A. Trapani, Mark J. Cowley, Paul J. Neeson, Paul G. Ekert
Published 2023-04-01