Therapeutic Targets in Diffuse Midline Gliomas—An Emerging Landscape

by Elisha Hayden, Holly Holliday, Rebecca Lehmann, Aaminah Khan, Maria Tsoli, Benjamin S. Rayner, David S. Ziegler
Published 2021-12-01

Depletion of white adipose tissue in cancer cachexia syndrome is associated with inflammatory signaling and disrupted circadian regulation.

by Maria Tsoli, Martina Schweiger, Anne S Vanniasinghe, Arran Painter, Rudolf Zechner, Stephen Clarke, Graham Robertson
Published 2014-01-01

Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models.

by Tammy Hennika, Guo Hu, Nagore G Olaciregui, Kelly L Barton, Anahid Ehteda, Arjanna Chitranjan, Cecilia Chang, Andrew J Gifford, Maria Tsoli, David S Ziegler, Angel M Carcaboso, Oren J Becher
Published 2017-01-01

Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas

by Aaminah Khan, Laura D. Gamble, Dannielle H. Upton, Caitlin Ung, Denise M. T. Yu, Anahid Ehteda, Ruby Pandher, Chelsea Mayoh, Steven Hébert, Nada Jabado, Claudia L. Kleinman, Mark R. Burns, Murray D. Norris, Michelle Haber, Maria Tsoli, David S. Ziegler
Published 2021-02-01

Doxorubicin-Loaded Gold Nanoarchitectures as a Therapeutic Strategy against Diffuse Intrinsic Pontine Glioma

by Caitlin Ung, Maria Tsoli, Jie Liu, Domenico Cassano, Salvador Pocoví-Martínez, Dannielle H. Upton, Anahid Ehteda, Friederike M. Mansfeld, Timothy W. Failes, Annafranca Farfalla, Christopher Katsinas, Maria Kavallaris, Greg M. Arndt, Orazio Vittorio, Giuseppe Cirillo, Valerio Voliani, David S. Ziegler
Published 2021-03-01

From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients

by Benedicte Grebstad Tune, Heena Sareen, Branka Powter, Smadar Kahana-Edwin, Adam Cooper, Eng-Siew Koh, Cheok S. Lee, Joseph W. Po, Geoff McCowage, Mark Dexter, Lucy Cain, Geraldine O’Neill, Victoria Prior, Jonathan Karpelowsky, Maria Tsoli, Lars O. Baumbusch, David Ziegler, Tara L. Roberts, Paul DeSouza, Therese M. Becker, Yafeng Ma
Published 2023-10-01

In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma

by Jacqueline P. Whitehouse, Jacqueline P. Whitehouse, Hilary Hii, Chelsea Mayoh, Chelsea Mayoh, Marie Wong, Marie Wong, Pamela Ajuyah, Paulette Barahona, Louise Cui, Hetal Dholaria, Hetal Dholaria, Hetal Dholaria, Christine L. White, Christine L. White, Christine L. White, Molly K. Buntine, Molly K. Buntine, Jacob Byrne, Keteryne Rodrigues da Silva, Keteryne Rodrigues da Silva, Meegan Howlett, Meegan Howlett, Emily J. Girard, Emily J. Girard, Maria Tsoli, Maria Tsoli, David S. Ziegler, David S. Ziegler, David S. Ziegler, Jason M. Dyke, Jason M. Dyke, Sharon Lee, Paul G. Ekert, Paul G. Ekert, Paul G. Ekert, Paul G. Ekert, Paul G. Ekert, Mark J. Cowley, Mark J. Cowley, Nicholas G. Gottardo, Nicholas G. Gottardo, Nicholas G. Gottardo, Raelene Endersby, Raelene Endersby
Published 2023-03-01

Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

by Anahid Ehteda, Sandy Simon, Laura Franshaw, Federico M. Giorgi, Jie Liu, Swapna Joshi, Jourdin R.C. Rouaen, Chi Nam Ignatius Pang, Ruby Pandher, Chelsea Mayoh, Yujie Tang, Aaminah Khan, Caitlin Ung, Ornella Tolhurst, Anne Kankean, Elisha Hayden, Rebecca Lehmann, Sylvie Shen, Anjana Gopalakrishnan, Peter Trebilcock, Katerina Gurova, Andrei V. Gudkov, Murray D. Norris, Michelle Haber, Orazio Vittorio, Maria Tsoli, David S. Ziegler
Published 2021-04-01

Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer

by Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Published 2023-07-01

In vitro and in vivo drug screens of tumor cells identify novel therapies for high‐risk child cancer

by Loretta M S Lau, Chelsea Mayoh, Jinhan Xie, Paulette Barahona, Karen L MacKenzie, Marie Wong, Alvin Kamili, Maria Tsoli, Tim W Failes, Amit Kumar, Emily V A Mould, Andrew Gifford, Shu‐Oi Chow, Mark Pinese, Jamie I Fletcher, Greg M Arndt, Dong‐Anh Khuong‐Quang, Carol Wadham, Daniel Batey, Georgina Eden, Peter Trebilcock, Swapna Joshi, Stephanie Alfred, Anjana Gopalakrishnan, Aaminah Khan, Dylan Grebert Wade, Patrick A Strong, Elodie Manouvrier, Lisa T Morgan, Miriam Span, Jin Yi Lim, Roxanne Cadiz, Caitlin Ung, David M Thomas, Katherine M Tucker, Meera Warby, Geoffrey B McCowage, Luciano Dalla‐Pozza, Jennifer A Byrne, Federica Saletta, Andrew Fellowes, Stephen B Fox, Murray D Norris, Vanessa Tyrrell, Toby N Trahair, Richard B Lock, Mark J Cowley, Paul G Ekert, Michelle Haber, David S Ziegler, Glenn M Marshall
Published 2022-04-01