Ring Finger Protein 125 Is an Anti-Proliferative Tumor Suppressor in Hepatocellular Carcinoma

by Takahiro Kodama, Michiko Kodama, Nancy A. Jenkins, Neal G. Copeland, Huanhuan Joyce Chen, Zhubo Wei
Published 2022-05-01

Fibrillar Inclusions and Motor Neuron Degeneration in Transgenic Mice Expressing Superoxide Dismutase 1 with a Disrupted Copper-Binding Site

by Jiou Wang, Guilian Xu, Victoria Gonzales, Michael Coonfield, David Fromholt, Neal G. Copeland, Nancy A. Jenkins, David R. Borchelt
Published 2002-07-01

Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA

by Jiou Wang, Guilian Xu, Hilda H. Slunt, Victoria Gonzales, Michael Coonfield, David Fromholt, Neal G. Copeland, Nancy A. Jenkins, David R. Borchelt
Published 2005-12-01

Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death

by Fabrice Bouilloux, Jérôme Thireau, Stéphanie Ventéo, Charlotte Farah, Sarah Karam, Yves Dauvilliers, Jean Valmier, Neal G Copeland, Nancy A Jenkins, Sylvain Richard, Frédéric Marmigère
Published 2016-02-01

Murine leukemias with retroviral insertions at Lmo2 are predictive of the leukemias induced in SCID-X1 patients following retroviral gene therapy.

by Utpal P Davé, Keiko Akagi, Rati Tripathi, Susan M Cleveland, Mary A Thompson, Ming Yi, Robert Stephens, James R Downing, Nancy A Jenkins, Neal G Copeland
Published 2009-05-01

Stability and Function of Hippocampal Mossy Fiber Synapses Depend on Bcl11b/Ctip2

by Elodie De Bruyckere, Ruth Simon, Sigrun Nestel, Bernd Heimrich, Dennis Kätzel, Alexei V. Egorov, Pentao Liu, Nancy A. Jenkins, Neal G. Copeland, Herbert Schwegler, Andreas Draguhn, Stefan Britsch
Published 2018-04-01

A Mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado–Joseph disease-like transgenic mice

by Veronica F. Colomer Gould, Daniel Goti, Donna Pearce, Guillermo A. Gonzalez, Hong Gao, Mario Bermudez de Leon, Nancy A. Jenkins, Neal G. Copeland, Christopher A. Ross, Dale R. Brown
Published 2007-09-01

Promoterless Transposon Mutagenesis Drives Solid Cancers via Tumor Suppressor Inactivation

by Aziz Aiderus, Ana M. Contreras-Sandoval, Amanda L. Meshey, Justin Y. Newberg, Jerrold M. Ward, Deborah A. Swing, Neal G. Copeland, Nancy A. Jenkins, Karen M. Mann, Michael B. Mann
Published 2021-01-01

Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease.

by Joanna L Jankowsky, Hilda H Slunt, Victoria Gonzales, Alena V Savonenko, Jason C Wen, Nancy A Jenkins, Neal G Copeland, Linda H Younkin, Henry A Lester, Steven G Younkin, David R Borchelt
Published 2005-12-01

Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin

by Yuji Tanaka, Shuichi Igarashi, Masayuki Nakamura, Juliette Gafni, Cameron Torcassi, Gabrielle Schilling, Danielle Crippen, Jonathan D. Wood, Akira Sawa, Nancy A. Jenkins, Neal G. Copeland, David R. Borchelt, Christopher A. Ross, Lisa M. Ellerby
Published 2006-02-01

Axonal Transport of Mutant Superoxide Dismutase 1 and Focal Axonal Abnormalities in the Proximal Axons of Transgenic Mice

by David R. Borchelt, Philip C. Wong, Mark W. Becher, Carlos A. Pardo, Michael K. Lee, Zuo-Shang Xu, Gopal Thinakaran, Nancy A. Jenkins, Neal G. Copeland, Sangram S. Sisodia, Don W. Cleveland, Donald L. Price, Paul N. Hoffman
Published 1998-07-01

Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis.

by Jesse D Riordan, Vincent W Keng, Barbara R Tschida, Todd E Scheetz, Jason B Bell, Kelly M Podetz-Pedersen, Catherine D Moser, Neal G Copeland, Nancy A Jenkins, Lewis R Roberts, David A Largaespada, Adam J Dupuy
Published 2013-04-01

Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.

by Emilie A Bard-Chapeau, Dorota Szumska, Bindya Jacob, Belinda Q L Chua, Gouri C Chatterjee, Yi Zhang, Jerrold M Ward, Fatma Urun, Emi Kinameri, Stéphane D Vincent, Sayadi Ahmed, Shoumo Bhattacharya, Motomi Osato, Archibald S Perkins, Adrian W Moore, Nancy A Jenkins, Neal G Copeland
Published 2014-01-01

LIM domain only-2 (LMO2) induces T-cell leukemia by two distinct pathways.

by Stephen Smith, Rati Tripathi, Charnise Goodings, Susan Cleveland, Elizabeth Mathias, J Andrew Hardaway, Natalina Elliott, Yajun Yi, Xi Chen, James Downing, Charles Mullighan, Deborah A Swing, Lino Tessarollo, Liqi Li, Paul Love, Nancy A Jenkins, Neal G Copeland, Mary Ann Thompson, Yang Du, Utpal P Davé
Published 2014-01-01

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

by David Ramonet, João Paulo L Daher, Brian M Lin, Klodjan Stafa, Jaekwang Kim, Rebecca Banerjee, Marie Westerlund, Olga Pletnikova, Liliane Glauser, Lichuan Yang, Ying Liu, Deborah A Swing, M Flint Beal, Juan C Troncoso, J Michael McCaffery, Nancy A Jenkins, Neal G Copeland, Dagmar Galter, Bobby Thomas, Michael K Lee, Ted M Dawson, Valina L Dawson, Darren J Moore
Published 2011-04-01

Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.

by Aziz Aiderus, Justin Y Newberg, Liliana Guzman-Rojas, Ana M Contreras-Sandoval, Amanda L Meshey, Devin J Jones, Felipe Amaya-Manzanares, Roberto Rangel, Jerrold M Ward, Song-Choon Lee, Kenneth Hon-Kim Ban, Keith Rogers, Susan M Rogers, Luxmanan Selvanesan, Leslie A McNoe, Neal G Copeland, Nancy A Jenkins, Kenneth Y Tsai, Michael A Black, Karen M Mann, Michael B Mann
Published 2021-08-01

Visualization and identification of IL-7 producing cells in reporter mice.

by Renata I Mazzucchelli, Søren Warming, Scott M Lawrence, Masaru Ishii, Mehrnoosh Abshari, A Valance Washington, Lionel Feigenbaum, Andrew C Warner, Davis J Sims, Wen Qing Li, Julie A Hixon, Daniel H D Gray, Benjamin E Rich, Matthew Morrow, Miriam R Anver, James Cherry, Dieter Naf, Lawrence R Sternberg, Daniel W McVicar, Andrew G Farr, Ronald N Germain, Keith Rogers, Nancy A Jenkins, Neal G Copeland, Scott K Durum
Published 2009-11-01