Mutational robustness changes during long-term adaptation in laboratory budding yeast populations

by Milo S Johnson, Michael M Desai
Published 2022-07-01

Global epistasis emerges from a generic model of a complex trait

by Gautam Reddy, Michael M Desai
Published 2021-03-01

Epistasis and evolution: recent advances and an outlook for prediction

by Milo S. Johnson, Gautam Reddy, Michael M. Desai
Published 2023-05-01

Yeast population dynamics in Brazilian bioethanol production

by Artur Rego-Costa, I Ting Huang, Michael M Desai, Andreas K Gombert
Published 2023-06-01

Genetic diversity in the interference selection limit.

by Benjamin H Good, Aleksandra M Walczak, Richard A Neher, Michael M Desai
Published 2014-03-01

Dynamics and variability in the pleiotropic effects of adaptation in laboratory budding yeast populations

by Christopher W Bakerlee, Angela M Phillips, Alex N Nguyen Ba, Michael M Desai
Published 2021-10-01

Modular epistasis and the compensatory evolution of gene deletion mutants.

by José I Rojas Echenique, Sergey Kryazhimskiy, Alex N Nguyen Ba, Michael M Desai
Published 2019-02-01

Inexpensive multiplexed library preparation for megabase-sized genomes.

by Michael Baym, Sergey Kryazhimskiy, Tami D Lieberman, Hattie Chung, Michael M Desai, Roy Kishony
Published 2015-01-01

The genetic basis of differential autodiploidization in evolving yeast populations

by Sudipta Tung, Christopher W Bakerlee, Angela M Phillips, Alex N Nguyen Ba, Michael M Desai
Published 2021-06-01

Genetic variation in adaptability and pleiotropy in budding yeast

by Elizabeth R Jerison, Sergey Kryazhimskiy, James Kameron Mitchell, Joshua S Bloom, Leonid Kruglyak, Michael M Desai
Published 2017-08-01

Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody

by Angela M Phillips, Daniel P Maurer, Caelan Brooks, Thomas Dupic, Aaron G Schmidt, Michael M Desai
Published 2023-01-01

Functional characterization of bacteria isolated from ancient arctic soil exposes diverse resistance mechanisms to modern antibiotics.

by Gabriel G Perron, Lyle Whyte, Peter J Turnbaugh, Jacqueline Goordial, William P Hanage, Gautam Dantas, Michael M Desai
Published 2015-01-01

Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast

by Alex N Nguyen Ba, Katherine R Lawrence, Artur Rego-Costa, Shreyas Gopalakrishnan, Daniel Temko, Franziska Michor, Michael M Desai
Published 2022-02-01

Binding affinity landscapes constrain the evolution of broadly neutralizing anti-influenza antibodies

by Angela M Phillips, Katherine R Lawrence, Alief Moulana, Thomas Dupic, Jeffrey Chang, Milo S Johnson, Ivana Cvijovic, Thierry Mora, Aleksandra M Walczak, Michael M Desai
Published 2021-09-01

The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast.

by David Gresham, Michael M Desai, Cheryl M Tucker, Harry T Jenq, Dave A Pai, Alexandra Ward, Christopher G DeSevo, David Botstein, Maitreya J Dunham
Published 2008-12-01

The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution

by Alief Moulana, Thomas Dupic, Angela M Phillips, Jeffrey Chang, Anne A Roffler, Allison J Greaney, Tyler N Starr, Jesse D Bloom, Michael M Desai
Published 2023-02-01

Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1

by Alief Moulana, Thomas Dupic, Angela M. Phillips, Jeffrey Chang, Serafina Nieves, Anne A. Roffler, Allison J. Greaney, Tyler N. Starr, Jesse D. Bloom, Michael M. Desai
Published 2022-11-01

Evolution of haploid and diploid populations reveals common, strong, and variable pleiotropic effects in non-home environments

by Vivian Chen, Milo S Johnson, Lucas Hérissant, Parris T Humphrey, David C Yuan, Yuping Li, Atish Agarwala, Samuel B Hoelscher, Dmitri A Petrov, Michael M Desai, Gavin Sherlock
Published 2023-10-01

The influenza hemagglutinin stem antibody CR9114: Evidence for a narrow evolutionary path towards universal protection

by Anna L. Beukenhorst, Anna L. Beukenhorst, Jacopo Frallicciardi, Clarissa M. Koch, Jaco M. Klap, Angela Phillips, Michael M. Desai, Kanin Wichapong, Gerry A. F. Nicolaes, Wouter Koudstaal, Galit Alter, Galit Alter, Jaap Goudsmit, Jaap Goudsmit
Published 2022-11-01

Corrigendum: The influenza hemagglutinin stem antibody CR9114: Evidence for a narrow evolutionary path towards universal protection

by Anna L. Beukenhorst, Anna L. Beukenhorst, Jacopo Frallicciardi, Clarissa M. Koch, Jaco M. Klap, Angela Phillips, Michael M. Desai, Kanin Wichapong, Gerry A. F. Nicolaes, Wouter Koudstaal, Galit Alter, Galit Alter, Jaap Goudsmit, Jaap Goudsmit
Published 2023-01-01