Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugged fitness landscape.

by Daniel J Kvitek, Gavin Sherlock
Published 2011-04-01

Whole genome, whole population sequencing reveals that loss of signaling networks is the major adaptive strategy in a constant environment.

by Daniel J Kvitek, Gavin Sherlock
Published 2013-11-01

Seeking Goldilocks During Evolution of Drug Resistance.

by Gavin Sherlock, Dmitri A Petrov
Published 2017-02-01

Adaptation is influenced by the complexity of environmental change during evolution in a dynamic environment.

by Sébastien Boyer, Lucas Hérissant, Gavin Sherlock
Published 2021-01-01

An improved algorithm for inferring mutational parameters from bar-seq evolution experiments

by Fangfei Li, Aditya Mahadevan, Gavin Sherlock
Published 2023-05-01

Changes in the distribution of fitness effects and adaptive mutational spectra following a single first step towards adaptation

by Dimitra Aggeli, Yuping Li, Gavin Sherlock
Published 2021-08-01

A genome-wide analysis reveals no nuclear dobzhansky-muller pairs of determinants of speciation between S. cerevisiae and S. paradoxus, but suggests more complex incompatibilities.

by Katy C Kao, Katja Schwartz, Gavin Sherlock
Published 2010-07-01

Bulk segregant analysis by high-throughput sequencing reveals a novel xylose utilization gene from Saccharomyces cerevisiae.

by Jared W Wenger, Katja Schwartz, Gavin Sherlock
Published 2010-05-01

iSeq: A New Double-Barcode Method for Detecting Dynamic Genetic Interactions in Yeast

by Mia Jaffe, Gavin Sherlock, Sasha F. Levy
Published 2017-01-01

Extremely Rare Polymorphisms in Saccharomyces cerevisiae Allow Inference of the Mutational Spectrum.

by Yuan O Zhu, Gavin Sherlock, Dmitri A Petrov
Published 2017-01-01

Whole Genome Analysis of 132 Clinical Saccharomyces cerevisiae Strains Reveals Extensive Ploidy Variation

by Yuan O. Zhu, Gavin Sherlock, Dmitri A. Petrov
Published 2016-08-01

Paths to adaptation under fluctuating nitrogen starvation: The spectrum of adaptive mutations in Saccharomyces cerevisiae is shaped by retrotransposons and microhomology-mediated r...

by Michelle Hays, Katja Schwartz, Danica T Schmidtke, Dimitra Aggeli, Gavin Sherlock
Published 2023-05-01

Acquisition, transmission and strain diversity of human gut-colonizing crAss-like phages

by Benjamin A. Siranosian, Fiona B. Tamburini, Gavin Sherlock, Ami S. Bhatt
Published 2020-01-01

Author Correction: Acquisition, transmission and strain diversity of human gut-colonizing crAss-like phages

by Benjamin A. Siranosian, Fiona B. Tamburini, Gavin Sherlock, Ami S. Bhatt
Published 2020-01-01

Novel low abundance and transient RNAs in yeast revealed by tiling microarrays and ultra high-throughput sequencing are not conserved across closely related yeast species.

by Albert Lee, Kasper Daniel Hansen, James Bullard, Sandrine Dudoit, Gavin Sherlock
Published 2008-12-01

Evolutionary dynamics and structural consequences of de novo beneficial mutations and mutant lineages arising in a constant environment

by Margie Kinnersley, Katja Schwartz, Dong-Dong Yang, Gavin Sherlock, Frank Rosenzweig
Published 2021-02-01

Ex uno plures: clonal reinforcement drives evolution of a simple microbial community.

by Margie Kinnersley, Jared Wenger, Evgueny Kroll, Julian Adams, Gavin Sherlock, Frank Rosenzweig
Published 2014-06-01

Neural networks enable efficient and accurate simulation-based inference of evolutionary parameters from adaptation dynamics.

by Grace Avecilla, Julie N Chuong, Fangfei Li, Gavin Sherlock, David Gresham, Yoav Ram
Published 2022-05-01

Hunger artists: yeast adapted to carbon limitation show trade-offs under carbon sufficiency.

by Jared W Wenger, Jeffrey Piotrowski, Saisubramanian Nagarajan, Kami Chiotti, Gavin Sherlock, Frank Rosenzweig
Published 2011-08-01

S. cerevisiae Cells Can Grow without the Pds5 Cohesin Subunit

by Karan Choudhary, Ziv Itzkovich, Elisa Alonso-Perez, Hend Bishara, Barbara Dunn, Gavin Sherlock, Martin Kupiec
Published 2022-08-01