Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects.

by Adam T Szafran, Maria Szwarc, Marco Marcelli, Michael A Mancini
Published 2008-01-01

Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures

by Adam T. Szafran, Maureen G. Mancini, Fabio Stossi, Michael A. Mancini
Published 2022-10-01

Leveraging Image-Derived Phenotypic Measurements for Drug-Target Interaction Predictions

by Srikanth Kuthuru, Adam T Szafran, Fabio Stossi, Michael A Mancini, Arvind Rao
Published 2019-06-01

Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis.

by Adam T Szafran, Fabio Stossi, Maureen G Mancini, Cheryl L Walker, Michael A Mancini
Published 2017-01-01

Activation of estrogen receptor-alpha by E2 or EGF induces temporally distinct patterns of large-scale chromatin modification and mRNA transcription.

by Valeria Berno, Larbi Amazit, Cruz Hinojos, Jeannie Zhong, Maureen G Mancini, Zelton Dave Sharp, Michael A Mancini
Published 2008-05-01

Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells.

by Fabio Stossi, Radhika D Dandekar, Hannah Johnson, Philip Lavere, Charles E Foulds, Maureen G Mancini, Michael A Mancini
Published 2019-01-01

Identification of celastrol as a novel HIV-1 latency reversal agent by an image-based screen.

by Hongbing Liu, Pei-Wen Hu, Julien Dubrulle, Fabio Stossi, Bryan C Nikolai, Michael A Mancini, Andrew P Rice
Published 2021-01-01

Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-α

by Michael J. Bolt, Pankaj Singh, Caroline E. Obkirchner, Reid T. Powell, Maureen G. Mancini, Adam T. Szafran, Fabio Stossi, Michael A. Mancini
Published 2021-11-01

A novel ERβ high throughput microscopy platform for testing endocrine disrupting chemicals

by Derek A. Abbott, Maureen G. Mancini, Michael J. Bolt, Adam T. Szafran, Kaley A. Neugebauer, Fabio Stossi, Daniel A. Gorelick, Michael A. Mancini
Published 2024-01-01

Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

by Pratim Chowdhury, Dimuthu Perera, Reid T. Powell, Tia Talley, Durga Nand Tripathi, Yong Sung Park, Michael A. Mancini, Peter Davies, Clifford Stephan, Cristian Corfa, Ruhee Dere
Published 2021-05-01

Author Correction: Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

by Pratim Chowdhury, Dimuthu Perera, Reid T. Powell, Tia Talley, Durga Nand Tripathi, Yong Sung Park, Michael A. Mancini, Peter Davies, Clifford Stephan, Cristian Coarfa, Ruhee Dere
Published 2021-08-01

Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms.

by Rajib Mukherjee, Burcu Beykal, Adam T Szafran, Melis Onel, Fabio Stossi, Maureen G Mancini, Dillon Lloyd, Fred A Wright, Lan Zhou, Michael A Mancini, Efstratios N Pistikopoulos
Published 2020-09-01

Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine.

by Adam T Szafran, Sean Hartig, Huiying Sun, Ivan P Uray, Maria Szwarc, Yuqing Shen, Sanjay N Mediwala, Jennifer Bell, Michael J McPhaul, Michael A Mancini, Marco Marcelli
Published 2009-12-01

Characterization of flavonoids with potent and subtype-selective actions on estrogen receptors alpha and beta

by Michael J. Bolt, Jessica Oceguera, Pankaj K. Singh, Kazem Safari, Derek H. Abbott, Kaley A. Neugebauer, Maureen G. Mancini, Daniel A. Gorelick, Fabio Stossi, Michael A. Mancini
Published 2024-03-01

Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies

by Hai Wang, Lin Tian, Amit Goldstein, Jun Liu, Hin-Ching Lo, Kuanwei Sheng, Thomas Welte, Stephen T.C. Wong, Zbigniew Gugala, Fabio Stossi, Chenghang Zong, Zonghai Li, Michael A. Mancini, Xiang H.-F. Zhang
Published 2017-04-01

The epidermal growth factor receptor critically regulates endometrial function during early pregnancy.

by Michael J Large, Margeaux Wetendorf, Rainer B Lanz, Sean M Hartig, Chad J Creighton, Michael A Mancini, Ertug Kovanci, Kuo-Fen Lee, David W Threadgill, John P Lydon, Jae-Wook Jeong, Francesco J DeMayo
Published 2014-06-01

Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress

by Wangjie Yu, Yunyun Chen, Nagireddy Putluri, Cristian Coarfa, Matthew J. Robertson, Vasanta Putluri, Fabio Stossi, Julien Dubrulle, Michael A. Mancini, Jonathan C. Pang, Trung Nguyen, Dodge Baluya, Jeffrey N. Myers, Stephen Y. Lai, Vlad C. Sandulache
Published 2020-06-01

Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis.

by Patrick M McDonough, Dominique Maciejewski-Lenoir, Sean M Hartig, Rita A Hanna, Ross Whittaker, Andrew Heisel, James B Nicoll, Benjamin M Buehrer, Kurt Christensen, Maureen G Mancini, Michael A Mancini, Dean P Edwards, Jeffrey H Price
Published 2013-01-01

The Human Nose Organoid Respiratory Virus Model: an Ex Vivo Human Challenge Model To Study Respiratory Syncytial Virus (RSV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SA...

by Anubama Rajan, Ashley Morgan Weaver, Gina Marie Aloisio, Joseph Jelinski, Hannah L. Johnson, Susan F. Venable, Trevor McBride, Letisha Aideyan, Felipe-Andrés Piedra, Xunyan Ye, Ernestina Melicoff-Portillo, Malli Rama Kanthi Yerramilli, Xi-Lei Zeng, Michael A. Mancini, Fabio Stossi, Anthony W. Maresso, Shalaka A. Kotkar, Mary K. Estes, Sarah Blutt, Vasanthi Avadhanula, Pedro A. Piedra
Published 2022-02-01