Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures

by Adam T. Szafran, Maureen G. Mancini, Fabio Stossi, Michael A. Mancini
Published 2022-10-01

Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis.

by Adam T Szafran, Fabio Stossi, Maureen G Mancini, Cheryl L Walker, Michael A Mancini
Published 2017-01-01

Activation of estrogen receptor-alpha by E2 or EGF induces temporally distinct patterns of large-scale chromatin modification and mRNA transcription.

by Valeria Berno, Larbi Amazit, Cruz Hinojos, Jeannie Zhong, Maureen G Mancini, Zelton Dave Sharp, Michael A Mancini
Published 2008-05-01

Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells.

by Fabio Stossi, Radhika D Dandekar, Hannah Johnson, Philip Lavere, Charles E Foulds, Maureen G Mancini, Michael A Mancini
Published 2019-01-01

Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-α

by Michael J. Bolt, Pankaj Singh, Caroline E. Obkirchner, Reid T. Powell, Maureen G. Mancini, Adam T. Szafran, Fabio Stossi, Michael A. Mancini
Published 2021-11-01

A novel ERβ high throughput microscopy platform for testing endocrine disrupting chemicals

by Derek A. Abbott, Maureen G. Mancini, Michael J. Bolt, Adam T. Szafran, Kaley A. Neugebauer, Fabio Stossi, Daniel A. Gorelick, Michael A. Mancini
Published 2024-01-01

Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms.

by Rajib Mukherjee, Burcu Beykal, Adam T Szafran, Melis Onel, Fabio Stossi, Maureen G Mancini, Dillon Lloyd, Fred A Wright, Lan Zhou, Michael A Mancini, Efstratios N Pistikopoulos
Published 2020-09-01

Characterization of flavonoids with potent and subtype-selective actions on estrogen receptors alpha and beta

by Michael J. Bolt, Jessica Oceguera, Pankaj K. Singh, Kazem Safari, Derek H. Abbott, Kaley A. Neugebauer, Maureen G. Mancini, Daniel A. Gorelick, Fabio Stossi, Michael A. Mancini
Published 2024-03-01

Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis.

by Patrick M McDonough, Dominique Maciejewski-Lenoir, Sean M Hartig, Rita A Hanna, Ross Whittaker, Andrew Heisel, James B Nicoll, Benjamin M Buehrer, Kurt Christensen, Maureen G Mancini, Michael A Mancini, Dean P Edwards, Jeffrey H Price
Published 2013-01-01