Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain

by Lynne Chantranupong, Jessica L Saulnier, Wengang Wang, Drew R Jones, Michael E Pacold, Bernardo L Sabatini
Published 2020-10-01

Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma

by Guisheng Zhao, Patrick Newbury, Yukitomo Ishi, Eugene Chekalin, Billy Zeng, Benjamin S. Glicksberg, Anita Wen, Shreya Paithankar, Takahiro Sasaki, Amreena Suri, Javad Nazarian, Michael E. Pacold, Daniel J. Brat, Theodore Nicolaides, Bin Chen, Rintaro Hashizume
Published 2022-10-01

Resurrecting essential amino acid biosynthesis in mammalian cells

by Julie Trolle, Ross M McBee, Andrew Kaufman, Sudarshan Pinglay, Henri Berger, Sergei German, Liyuan Liu, Michael J Shen, Xinyi Guo, J Andrew Martin, Michael E Pacold, Drew R Jones, Jef D Boeke, Harris H Wang
Published 2022-09-01

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

by Schraga Schwartz, Maxwell R. Mumbach, Marko Jovanovic, Tim Wang, Karolina Maciag, G. Guy Bushkin, Philipp Mertins, Dmitry Ter-Ovanesyan, Naomi Habib, Davide Cacchiarelli, Neville E. Sanjana, Elizaveta Freinkman, Michael E. Pacold, Rahul Satija, Tarjei S. Mikkelsen, Nir Hacohen, Feng Zhang, Steven A. Carr, Eric S. Lander, Aviv Regev
Published 2014-07-01

PIK3CA mutant tumors depend on oxoglutarate dehydrogenase

by Ilic, Nina, Kıvanç Birsoy, Aguirre, Andrew, Kory, Nora, Pacold, Michael, Singh, Shambhavi, Moody, Susan, DeAngelo, Joseph, Spardy, Nicole, Freinkman, Elizaveta, Weir, Barbara, Tsherniak, Aviad, Cowley, Glenn, Root, David, Asara, John, Vazquez, Francisca, Widlund, Hans, Sabatini, David, Hahn, William
Published 2019

The bromodomain protein Brd4 insulates chromatin from DNA damage signalling

by Floyd, Scott R., Pacold, Michael E., Huang, Qiuying, Clarke, Scott M., Rameseder, Jonathan, Lee, Michael J., Blake, Emily J., Fydrych, Anna, Ho, Richard, Del Rosario, Amanda M., Root, David E., Carpenter, Anne E., Hahn, William C., Sabatini, David M., Chen, Clark C., White, Forest M., Bradner, James E., Yaffe, Michael B., Lam, Fred Chiu-Lai, Cannell, Ian Gordon, Bryson, Bryan D., Greenberger, Benjamin Aaron, Chen, Grace, Maffa, Amanda D.
Published 2014