Restoring Treatment Response in Colorectal Cancer Cells by Targeting MACC1-Dependent ABCB1 Expression in Combination Therapy

by Mathias Dahlmann, Mathias Dahlmann, Rebecca Werner, Benedikt Kortüm, Dennis Kobelt, Wolfgang Walther, Ulrike Stein, Ulrike Stein
Published 2020-04-01

S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction

by Mathias Dahlmann, Dennis Kobelt, Wolfgang Walther, Giridhar Mudduluru, Ulrike Stein
Published 2016-06-01

Core-Clock Genes Regulate Proliferation and Invasion via a Reciprocal Interplay with MACC1 in Colorectal Cancer Cells

by Alireza Basti, Deeksha Malhan, Malti Dumbani, Mathias Dahlmann, Ulrike Stein, Angela Relógio
Published 2022-07-01

MACC1-Induced Collective Migration Is Promoted by Proliferation Rather Than Single Cell Biomechanics

by Tim Hohmann, Urszula Hohmann, Mathias Dahlmann, Dennis Kobelt, Ulrike Stein, Faramarz Dehghani
Published 2022-06-01

MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma

by Tim Hohmann, Urszula Hohmann, Marc R. Kolbe, Mathias Dahlmann, Dennis Kobelt, Ulrike Stein, Faramarz Dehghani
Published 2020-06-01

Small Ones to Fight a Big Problem—Intervention of Cancer Metastasis by Small Molecules

by Dennis Kobelt, Mathias Dahlmann, Malti Dumbani, Nazli Güllü, Benedikt Kortüm, Miguel E. Alberto Vílchez, Ulrike Stein, Wolfgang Walther
Published 2020-06-01

Combination of Wnt/β-Catenin Targets S100A4 and DKK1 Improves Prognosis of Human Colorectal Cancer

by Mathias Dahlmann, Anne Monks, Erik D. Harris, Dennis Kobelt, Marc Osterland, Fadi Khaireddine, Pia Herrmann, Wolfgang Kemmner, Susen Burock, Wolfgang Walther, Robert H. Shoemaker, Ulrike Stein
Published 2021-12-01

Circulating MACC1 Transcripts in Glioblastoma Patients Predict Prognosis and Treatment Response

by Carsten Hagemann, Nikolas Neuhaus, Mathias Dahlmann, Almuth F. Kessler, Dennis Kobelt, Pia Herrmann, Matthias Eyrich, Benjamin Freitag, Thomas Linsenmann, Camelia M. Monoranu, Ralf-Ingo Ernestus, Mario Löhr, Ulrike Stein
Published 2019-06-01

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.

by Manisha Juneja, Dennis Kobelt, Wolfgang Walther, Cynthia Voss, Janice Smith, Edgar Specker, Martin Neuenschwander, Björn-Oliver Gohlke, Mathias Dahlmann, Silke Radetzki, Robert Preissner, Jens Peter von Kries, Peter Michael Schlag, Ulrike Stein
Published 2017-06-01

Establishment and Thorough Characterization of Xenograft (PDX) Models Derived from Patients with Pancreatic Cancer for Molecular Analyses and Chemosensitivity Testing

by Diana Behrens, Ulrike Pfohl, Theresia Conrad, Michael Becker, Bernadette Brzezicha, Britta Büttner, Silvia Wagner, Cora Hallas, Rita Lawlor, Vladimir Khazak, Michael Linnebacher, Thomas Wartmann, Iduna Fichtner, Jens Hoffmann, Mathias Dahlmann, Wolfgang Walther
Published 2023-12-01

Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models

by Mathias Dahlmann, Guido Gambara, Bernadette Brzezicha, Oliver Popp, Eva Pachmayr, Lena Wedeken, Alina Pflaume, Margarita Mokritzkij, Safak Gül-Klein, Andreas Brandl, Caroline Schweiger-Eisbacher, Philipp Mertins, Jens Hoffmann, Ulrich Keilholz, Wolfgang Walther, Christian Regenbrecht, Beate Rau, Ulrike Stein
Published 2021-10-01

Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures

by Joshua Alcaniz, Lars Winkler, Mathias Dahlmann, Michael Becker, Andrea Orthmann, Johannes Haybaeck, Johannes Haybaeck, Johannes Haybaeck, Stefanie Krassnig, Christina Skofler, Tobias Kratzsch, Susanne A. Kuhn, Andreas Jödicke, Michael Linnebacher, Iduna Fichtner, Wolfgang Walther, Wolfgang Walther, Wolfgang Walther, Jens Hoffmann
Published 2023-04-01

A Molecularly Characterized Preclinical Platform of Subcutaneous Renal Cell Carcinoma (RCC) Patient-Derived Xenograft Models to Evaluate Novel Treatment Strategies

by Dennis Gürgen, Michael Becker, Mathias Dahlmann, Susanne Flechsig, Elke Schaeffeler, Elke Schaeffeler, Elke Schaeffeler, Florian A. Büttner, Christian Schmees, Regina Bohnert, Jens Bedke, Jens Bedke, Matthias Schwab, Matthias Schwab, Matthias Schwab, Matthias Schwab, Johann J. Wendler, Martin Schostak, Burkhard Jandrig, Wolfgang Walther, Wolfgang Walther, Wolfgang Walther, Jens Hoffmann
Published 2022-06-01