Co‐targeting driver pathways in prostate cancer: two birds with one stone

by Amina Zoubeidi, Martin E Gleave
Published 2018-04-01

Therapeutic Efficacy of Adenoviral-Mediated p53 Gene Transfer Is Synergistically Enhanced by Combined Use of Antisense Oligodeoxynucleotide Targeting Clusterin Gene in a Human Blad...

by Hideaki Miyake, Kazuki Yamanaka, Mototsugu Muramaki, Isao Hara, Martin E. Gleave
Published 2005-02-01

Chemosensitization of Human Renal Cell Cancer Using Antisense Oligonucleotides Targeting the Antiapoptotic Gene Clusterin

by Tobias Zellweger, Hideaki Miyake, Laura V. July, Majid Akbari, Satoshi Kiyama, Martin E. Gleave
Published 2001-01-01

Steroidogenesis in Peripheral and Transition Zones of Human Prostate Cancer Tissue

by Subrata Deb, Mei Yieng Chin, Steven Pham, Hans Adomat, Antonio Hurtado-Coll, Martin E. Gleave, Emma S. Tomlinson Guns
Published 2021-01-01

Development of Novel Inhibitors Targeting the D-Box of the DNA Binding Domain of Androgen Receptor

by Mariia Radaeva, Fuqiang Ban, Fan Zhang, Eric LeBlanc, Nada Lallous, Paul S. Rennie, Martin E. Gleave, Artem Cherkasov
Published 2021-03-01

Plasma miRNAs as Biomarkers to Identify Patients with Castration-Resistant Metastatic Prostate Cancer

by Kim N. Chi, Cheryl D. Helgason, Francesco Crea, Yuzhuo Wang, Martin E. Gleave, Akira Watahiki, Robyn J. Macfarlane
Published 2013-04-01

Deep Docking: A Deep Learning Platform for Augmentation of Structure Based Drug Discovery

by Francesco Gentile, Vibudh Agrawal, Michael Hsing, Anh-Tien Ton, Fuqiang Ban, Ulf Norinder, Martin E. Gleave, Artem Cherkasov
Published 2020-05-01

Characterization of Precursor-Dependent Steroidogenesis in Human Prostate Cancer Models

by Subrata Deb, Steven Pham, Dong-Sheng Ming, Mei Yieng Chin, Hans Adomat, Antonio Hurtado-Coll, Martin E. Gleave, Emma S. Tomlinson Guns
Published 2018-09-01

Evaluation of Darolutamide (ODM201) Efficiency on Androgen Receptor Mutants Reported to Date in Prostate Cancer Patients

by Nada Lallous, Oliver Snow, Christophe Sanchez, Ana Karla Parra Nuñez, Bei Sun, Ahmed Hussain, Joseph Lee, Helene Morin, Eric Leblanc, Martin E. Gleave, Artem Cherkasov
Published 2021-06-01

Cellular Adaptation to VEGF-Targeted Antiangiogenic Therapy Induces Evasive Resistance by Overproduction of Alternative Endothelial Cell Growth Factors in Renal Cell Carcinoma

by Kyung Seok Han, Peter A. Raven, Sebastian Frees, Kilian Gust, Ladan Fazli, Susan Ettinger, Sung Joon Hong, Cristian Kollmannsberger, Martin E. Gleave, Alan I. So
Published 2015-11-01

Systematic identification and characterization of RNA editing in prostate tumors.

by Fan Mo, Alexander W Wyatt, Yue Sun, Sonal Brahmbhatt, Brian J McConeghy, Chunxiao Wu, Yuzhuo Wang, Martin E Gleave, Stanislav V Volik, Colin C Collins
Published 2014-01-01

Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability.

by Jennifer H Law, Yvonne Li, Karen To, Michelle Wang, Arezoo Astanehe, Karen Lambie, Jaspreet Dhillon, Steven J M Jones, Martin E Gleave, Connie J Eaves, Sandra E Dunn
Published 2010-09-01

A noncanonical AR addiction drives enzalutamide resistance in prostate cancer

by Yundong He, Ting Wei, Zhenqing Ye, Jacob J. Orme, Dong Lin, Haoyue Sheng, Ladan Fazli, R. Jeffrey Karnes, Rafael Jimenez, Liguo Wang, Liewei Wang, Martin E. Gleave, Yuzhuo Wang, Lei Shi, Haojie Huang
Published 2021-03-01

Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer

by Kevin J. Tam, Liangliang Liu, Michael Hsing, Kush Dalal, Daksh Thaper, Brian McConeghy, Parvin Yenki, Satyam Bhasin, James W. Peacock, Yuzhuo Wang, Artem Cherkasov, Paul S. Rennie, Martin E. Gleave, Christopher J. Ong
Published 2024-03-01

Targeting MCT4 to reduce lactic acid secretion and glycolysis for treatment of neuroendocrine prostate cancer

by Stephen Yiu Chuen Choi, Susan L. Ettinger, Dong Lin, Hui Xue, Xinpei Ci, Noushin Nabavi, Robert H. Bell, Fan Mo, Peter W. Gout, Neil E. Fleshner, Martin E. Gleave, Colin C. Collins, Yuzhuo Wang
Published 2018-07-01

Discovery of New Catalytic Topoisomerase II Inhibitors for Anticancer Therapeutics

by Victor M. Matias-Barrios, Mariia Radaeva, Yi Song, Yi Song, Zaccary Alperstein, Ahn R. Lee, Veronika Schmitt, Joseph Lee, Fuqiang Ban, Ning Xie, Jianfei Qi, Nada Lallous, Martin E. Gleave, Artem Cherkasov, Xuesen Dong
Published 2021-02-01

Development of an Androgen Receptor Inhibitor Targeting the N-Terminal Domain of Androgen Receptor for Treatment of Castration Resistant Prostate Cancer

by Fuqiang Ban, Eric Leblanc, Ayse Derya Cavga, Chia-Chi Flora Huang, Mark R. Flory, Fan Zhang, Matthew E. K. Chang, Hélène Morin, Nada Lallous, Kriti Singh, Martin E. Gleave, Hisham Mohammed, Paul S. Rennie, Nathan A. Lack, Artem Cherkasov
Published 2021-07-01

CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation

by Zheng Wang, Mohit Hulsurkar, Lijuan Zhuo, Jinbang Xu, Han Yang, Samira Naderinezhad, Lin Wang, Guoliang Zhang, Nanping Ai, Linna Li, Jeffrey T. Chang, Songlin Zhang, Ladan Fazli, Chad J. Creighton, Fang Bai, Michael M. Ittmann, Martin E. Gleave, Wenliang Li
Published 2021-11-01

DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2

by Roosa Kaarijärvi, Heidi Kaljunen, Lucia Nappi, Ladan Fazli, Sonia H. Y. Kung, Jaana M. Hartikainen, Ville Paakinaho, Janne Capra, Kirsi Rilla, Marjo Malinen, Petri I. Mäkinen, Seppo Ylä-Herttuala, Amina Zoubeidi, Yuzhuo Wang, Martin E. Gleave, Mikko Hiltunen, Kirsi Ketola
Published 2024-01-01

The novel BET‐CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild‐type prostate cancer

by Yuqian Yan, Jian Ma, Dejie Wang, Dong Lin, Xiaodong Pang, Shangqian Wang, Yu Zhao, Lei Shi, Hui Xue, Yunqian Pan, Jun Zhang, Claes Wahlestedt, Francis J Giles, Yu Chen, Martin E Gleave, Collin C Collins, Dingwei Ye, Yuzhuo Wang, Haojie Huang
Published 2019-11-01