Altered Fibroblast Growth Factor Receptor 4 Stability Promotes Prostate Cancer Progression

by Jianghua Wang, Wendong Yu, Yi Cai, Chengxi Ren, Michael M. Ittmann
Published 2008-08-01

Aberrant Activation of the RANK Signaling Receptor Induces Murine Salivary Gland Tumors.

by Maria M Szwarc, Ramakrishna Kommagani, Allison P Jacob, William C Dougall, Michael M Ittmann, John P Lydon
Published 2015-01-01

Correction: ERManI Is a Target of miR-125b and Promotes Transformation Phenotypes in Hepatocellular Carcinoma (HCC).

by Shujuan Pan, Xiaoyun Cheng, Hongan Chen, Patricia D. Castro, Michael M. Ittmann, Anne W. Hutson, Susan K. Zapata, Richard N. Sifers
Published 2014-01-01

ERManI is a target of miR-125b and promotes transformation phenotypes in hepatocellular carcinoma (HCC).

by Shujuan Pan, Xiaoyun Cheng, Hongan Chen, Patricia D Castro, Michael M Ittmann, Anne W Hutson, Susan K Zapata, Richard N Sifers
Published 2013-01-01

Spatial Profiling of the Prostate Cancer Tumor Microenvironment Reveals Multiple Differences in Gene Expression and Correlation with Recurrence Risk

by Vinay Kumar, Pavneet Randhawa, Robert Bilodeau, Dan Mercola, Michael McClelland, Anshu Agrawal, James Nguyen, Patricia Castro, Michael M. Ittmann, Farah Rahmatpanah
Published 2022-10-01

Characterizing treatment resistance in muscle invasive bladder cancer using the chicken egg chorioallantoic membrane patient-derived xenograft model

by Hugo Villanueva, Gabrielle A. Wells, Malachi T. Miller, Mariana Villanueva, Ravi Pathak, Patricia Castro, Michael M. Ittmann, Andrew G. Sikora, Seth P. Lerner
Published 2022-12-01

Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer

by Shih-Chieh Lin, Chung-Yang Kao, Hui-Ju Lee, Chad J. Creighton, Michael M. Ittmann, Shaw-Jenq Tsai, Sophia Y. Tsai, Ming-Jer Tsai
Published 2016-04-01

INPP4B protects from metabolic syndrome and associated disorders

by Manqi Zhang, Yasemin Ceyhan, Elena M. Kaftanovskaya, Judy L. Vasquez, Jean Vacher, Filip K. Knop, Lubov Nathanson, Alexander I. Agoulnik, Michael M. Ittmann, Irina U. Agoulnik
Published 2021-03-01

Systemic Ablation of <i>Camkk2</i> Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate C...

by Thomas L. Pulliam, Dominik Awad, Jenny J. Han, Mollianne M. Murray, Jeffrey J. Ackroyd, Pavithr Goli, Jonathan S. Oakhill, John W. Scott, Michael M. Ittmann, Daniel E. Frigo
Published 2022-06-01

Repair-Assisted Damage Detection Reveals Biological Disparities in Prostate Cancer between African Americans and European Americans

by Kimiko L. Krieger, Jie H. Gohlke, Kevin J. Lee, Danthasinghe Waduge Badrajee Piyarathna, Patricia D. Castro, Jeffrey A. Jones, Michael M. Ittmann, Natalie R. Gassman, Arun Sreekumar
Published 2022-02-01

CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT

by Arindam Chaudhury, Shebna Cheema, Joseph M. Fachini, Natee Kongchan, Guojun Lu, Lukas M. Simon, Tao Wang, Sufeng Mao, Daniel G. Rosen, Michael M. Ittmann, Susan G. Hilsenbeck, Chad A. Shaw, Joel R. Neilson
Published 2016-11-01

Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis.

by Payam Shahi, Dongsu Park, Adam C Pond, Mamatha Seethammagari, Shin-Heng Chiou, Kyucheol Cho, Julienne L Carstens, William K Decker, Pierre D McCrea, Michael M Ittmann, Jeffrey M Rosen, David M Spencer
Published 2012-01-01

A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis

by Wei Wang, Yanling Meng, Bingning Dong, Jie Dong, Michael M. Ittmann, Chad J. Creighton, Yang Lu, Hong Zhang, Tao Shen, Jianghua Wang, David R. Rowley, Yi Li, Fengju Chen, David D. Moore, Feng Yang
Published 2017-05-01

SMAD2/3 signaling in the uterine epithelium controls endometrial cell homeostasis and regeneration

by Maya L. Kriseman, Suni Tang, Zian Liao, Peixin Jiang, Sydney E. Parks, Dominique I. Cope, Fei Yuan, Fengju Chen, Ramya P. Masand, Patricia D. Castro, Michael M. Ittmann, Chad J. Creighton, Zhi Tan, Diana Monsivais
Published 2023-03-01

JNK1/2 represses Lkb 1-deficiency-induced lung squamous cell carcinoma progression

by Jian Liu, Tianyuan Wang, Chad J. Creighton, San-Pin Wu, Madhumita Ray, Kyathanahalli S. Janardhan, Cynthia J. Willson, Sung-Nam Cho, Patricia D. Castro, Michael M. Ittmann, Jian-Liang Li, Roger J. Davis, Francesco J. DeMayo
Published 2019-05-01

CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation

by Zheng Wang, Mohit Hulsurkar, Lijuan Zhuo, Jinbang Xu, Han Yang, Samira Naderinezhad, Lin Wang, Guoliang Zhang, Nanping Ai, Linna Li, Jeffrey T. Chang, Songlin Zhang, Ladan Fazli, Chad J. Creighton, Fang Bai, Michael M. Ittmann, Martin E. Gleave, Wenliang Li
Published 2021-11-01

Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells.

by Nicholes R Candelaria, Sridevi Addanki, Jine Zheng, Trang Nguyen-Vu, Husna Karaboga, Prasenjit Dey, Chiara Gabbi, Lise-Lotte Vedin, Ka Liu, Wanfu Wu, Philip K Jonsson, Jean Z Lin, Fei Su, Lakshmi Reddy Bollu, Sally E Hodges, Amy L McElhany, Mehdi A Issazadeh, William E Fisher, Michael M Ittmann, Knut R Steffensen, Jan-Åke Gustafsson, Chin-Yo Lin
Published 2014-01-01

Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer

by Akash K. Kaushik, Ali Shojaie, Katrin Panzitt, Rajni Sonavane, Harene Venghatakrishnan, Mohan Manikkam, Alexander Zaslavsky, Vasanta Putluri, Vihas T. Vasu, Yiqing Zhang, Ayesha S. Khan, Stacy Lloyd, Adam T. Szafran, Subhamoy Dasgupta, David A. Bader, Fabio Stossi, Hangwen Li, Susmita Samanta, Xuhong Cao, Efrosini Tsouko, Shixia Huang, Daniel E. Frigo, Lawrence Chan, Dean P. Edwards, Benny A. Kaipparettu, Nicholas Mitsiades, Nancy L. Weigel, Michael Mancini, Sean E. McGuire, Rohit Mehra, Michael M. Ittmann, Arul M. Chinnaiyan, Nagireddy Putluri, Ganesh S. Palapattu, George Michailidis, Arun Sreekumar
Published 2016-05-01

Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation

by Marie-Claude Gingras, Kyle R. Covington, David K. Chang, Lawrence A. Donehower, Anthony J. Gill, Michael M. Ittmann, Chad J. Creighton, Amber L. Johns, Eve Shinbrot, Ninad Dewal, William E. Fisher, Christian Pilarsky, Robert Grützmann, Michael J. Overman, Nigel B. Jamieson, George Van Buren II, Jennifer Drummond, Kimberly Walker, Oliver A. Hampton, Liu Xi, Donna M. Muzny, Harsha Doddapaneni, Sandra L. Lee, Michelle Bellair, Jianhong Hu, Yi Han, Huyen H. Dinh, Mike Dahdouli, Jaswinder S. Samra, Peter Bailey, Nicola Waddell, John V. Pearson, Ivon Harliwong, Huamin Wang, Daniela Aust, Karin A. Oien, Ralph H. Hruban, Sally E. Hodges, Amy McElhany, Charupong Saengboonmee, Fraser R. Duthie, Sean M. Grimmond, Andrew V. Biankin, David A. Wheeler, Richard A. Gibbs
Published 2016-02-01