Editorial: Innovative pharmacometric approaches to inform drug development and clinical use

by Maria Garcia-Cremades, Maria Garcia-Cremades, Zinnia P. Parra-Guillen, Zinnia P. Parra-Guillen, Victor Mangas-Sanjuan, Victor Mangas-Sanjuan, Hugo Geerts
Published 2023-10-01

Mechanistic Multiscale Pharmacokinetic Model for the Anticancer Drug 2’,2’‐difluorodeoxycytidine (Gemcitabine) in Pancreatic Cancer

by Maria Garcia‐Cremades, Nicola Melillo, Iñaki F. Troconiz, Paolo Magni
Published 2020-05-01

A Mechanistic In Vivo/Ex Vivo Pharmacokinetic‐Pharmacodynamic Model of Tenofovir for HIV Prevention

by Priya Jayachandran, Maria Garcia-Cremades, Katarina Vučićević, Namandjé N. Bumpus, Peter Anton, Craig Hendrix, Radojka Savić
Published 2021-03-01

Oxypurinol pharmacokinetics and pharmacodynamics in healthy volunteers: Influence of BCRP Q141K polymorphism and patient characteristics

by Bianca Vora, Deanna J. Brackman, Ling Zou, Maria Garcia‐Cremades, Marina Sirota, Radojka M. Savic, Kathleen M. Giacomini
Published 2021-07-01

Population Pharmacokinetic/Pharmacodynamic Modelling of Daptomycin for Schedule Optimization in Patients with Renal Impairment

by Teresa García-Martínez, María Dolores Bellés-Medall, Maria García-Cremades, Raúl Ferrando-Piqueres, Victor Mangas-Sanjuán, Matilde Merino-Sanjuan
Published 2022-10-01

Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies.

by Anthony J Garcia-Prats, H Simon Schaaf, Heather R Draper, Maria Garcia-Cremades, Jana Winckler, Lubbe Wiesner, Anneke C Hesseling, Rada M Savic
Published 2019-04-01

Modeling the Probability of HIV Infection over Time in High-Risk Seronegative Participants Receiving Placebo in Five Randomized Double-Blind Placebo-Controlled HIV Pre-Exposure Pro...

by Maria Garcia-Cremades, Craig W. Hendrix, Priya Jayachandran, Natasha Strydom, Leah Jarlsberg, Robert Grant, Connie L. Celum, Michael Martin, Jared M. Baeten, Jeanne Marrazzo, Peter Anderson, Kachit Choopanya, Suphak Vanichseni, David V. Glidden, Radojka M. Savic
Published 2022-08-01

Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens

by Nicholas D. Walter, Sarah E. M. Born, Gregory T. Robertson, Matthew Reichlen, Christian Dide-Agossou, Victoria A. Ektnitphong, Karen Rossmassler, Michelle E. Ramey, Allison A. Bauman, Victor Ozols, Shelby C. Bearrows, Gary Schoolnik, Gregory Dolganov, Benjamin Garcia, Emmanuel Musisi, William Worodria, Laurence Huang, J. Lucian Davis, Nhung V. Nguyen, Hung V. Nguyen, Anh T. V. Nguyen, Ha Phan, Carol Wilusz, Brendan K. Podell, N’ Dira Sanoussi, Bouke C. de Jong, Corinne S. Merle, Dissou Affolabi, Helen McIlleron, Maria Garcia-Cremades, Ekaterina Maidji, Franceen Eshun-Wilson, Brandon Aguilar-Rodriguez, Dhuvarakesh Karthikeyan, Khisimuzi Mdluli, Cathy Bansbach, Anne J. Lenaerts, Radojka M. Savic, Payam Nahid, Joshua J. Vásquez, Martin I. Voskuil
Published 2021-05-01