Discovery of Genetic Variants of the Kinases That Activate Tenofovir in a Compartment-specific Manner

by Julie M. Lade, Elaine E. To, Craig W. Hendrix, Namandjé N. Bumpus
Published 2015-09-01

Clinical trial simulation to evaluate tenofovir disoproxil fumarate/emtricitabine HIV pre-exposure prophylaxis dosing during pregnancy

by Rachel K. Scott, Yifan Yu, Mark A. Marzinke, Jenell S. Coleman, Craig W. Hendrix, Robert Bies
Published 2023-09-01

Assessment of Demographic and Socio-Behavioral Factors on Adherence to HIV Pre-Exposure Prophylaxis Using a Markov Modeling Approach

by Surulivelrajan Mallayasamy, Ayyappa Chaturvedula, Michael J. Fossler, Michael J. Fossler, Mark E. Sale, Mark E. Sale, Craig W. Hendrix, Jessica E. Haberer
Published 2019-07-01

Vaginal washing and lubrication among female sex workers in the Mexico-US border region: implications for the development of vaginal PrEP for HIV prevention

by Heather A. Pines, Shirley J. Semple, Steffanie A. Strathdee, Craig W. Hendrix, Alicia Harvey-Vera, Pamina M. Gorbach, Carlos Magis-Rodríguez, Gustavo Martinez, Thomas L. Patterson
Published 2018-08-01

Pharmacokinetics of tenofovir alafenamide, emtricitabine, and dolutegravir in a patient on peritoneal dialysis

by Sandra Abdul Massih, Mohamed G. Atta, Chloe L. Thio, Jeffrey A. Tornheim, Edward J. Fuchs, Rahul P. Bakshi, Mark A. Marzinke, Craig W. Hendrix, Ethel D. Weld
Published 2024-05-01

Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study.

by Nicola Richardson-Harman, Craig W Hendrix, Namandjé N Bumpus, Christine Mauck, Ross D Cranston, Kuo Yang, Julie Elliott, Karen Tanner, Ian McGowan, Angela Kashuba, Peter A Anton
Published 2014-01-01

Phase I trial of pod-intravaginal rings delivering antiretroviral agents for HIV-1 prevention: Rectal drug exposure from vaginal dosing with tenofovir disoproxil fumarate, emtricit...

by Kathleen Listiak Vincent, John A Moss, Mark A Marzinke, Craig W Hendrix, Peter A Anton, Manjula Gunawardana, Lauren N Dawson, Trevelyn J Olive, Richard B Pyles, Marc M Baum
Published 2018-01-01

Performance of swabs, lavage, and diluents to quantify biomarkers of female genital tract soluble mucosal mediators.

by Charlene S Dezzutti, Craig W Hendrix, Jeanne M Marrazzo, Zhenyu Pan, Lei Wang, Nicolette Louissaint, Sabah Kalyoussef, N Merna Torres, Florian Hladik, Urvi Parikh, John Mellors, Sharon L Hillier, Betsy C Herold
Published 2011-01-01

Correction: Performance of Swabs, Lavage, and Diluents to Quantify Biomarkers of Female Genital Tract Soluble Mucosal Mediators.

by Charlene S. Dezzutti, Craig W. Hendrix, Jeanne M. Marrazzo, Zhenyu Pan, Lei Wang, Nicolette Louissaint, Sabah Kalyoussef, N. Merna Torres, Florian Hladik, Urvi Parikh, John Mellors, Sharon L. Hillier, Betsy C. Herold
Published 2012-01-01

Hypo-osmolar rectal douche tenofovir formulation prevents simian/human immunodeficiency virus acquisition in macaques

by Peng Xiao, Sanjeev Gumber, Mark A. Marzinke, Thuy Hoang, Rohan Myers, Abhijit A. Date, Justin Hanes, Laura M. Ensign, Lin Wang, Lisa C. Rohan, Richard Cone, Edward J. Fuchs, Craig W. Hendrix, Francois Villinger
Published 2022-12-01

MTN-001: randomized pharmacokinetic cross-over study comparing tenofovir vaginal gel and oral tablets in vaginal tissue and other compartments.

by Craig W Hendrix, Beatrice A Chen, Vijayanand Guddera, Craig Hoesley, Jessica Justman, Clemensia Nakabiito, Robert Salata, Lydia Soto-Torres, Karen Patterson, Alexandra M Minnis, Sharavi Gandham, Kailazarid Gomez, Barbra A Richardson, Namandje N Bumpus
Published 2013-01-01

Pre-exposure Prophylaxis Use by Breastfeeding HIV-Uninfected Women: A Prospective Short-Term Study of Antiretroviral Excretion in Breast Milk and Infant Absorption.

by Kenneth K Mugwanya, Craig W Hendrix, Nelly R Mugo, Mark Marzinke, Elly T Katabira, Kenneth Ngure, Nulu B Semiyaga, Grace John-Stewart, Timothy R Muwonge, Gabriel Muthuri, Andy Stergachis, Connie L Celum, Jared M Baeten
Published 2016-09-01

Novel multipurpose pod-intravaginal ring for the prevention of HIV, HSV, and unintended pregnancy: Pharmacokinetic evaluation in a macaque model.

by James M Smith, John A Moss, Priya Srinivasan, Irina Butkyavichene, Manjula Gunawardana, Rob Fanter, Christine S Miller, Debbie Sanchez, Flora Yang, Shanon Ellis, Jining Zhang, Mark A Marzinke, Craig W Hendrix, Amita Kapoor, Marc M Baum
Published 2017-01-01

Discovery of genetic variants of the kinases that activate tenofovir among individuals in the United States, Thailand, and South Africa: HPTN067.

by Dominique B Figueroa, Joseph Tillotson, Maoji Li, Estelle Piwowar-Manning, Craig W Hendrix, Timothy H Holtz, Kevin Bokoch, Linda-Gail Bekker, Frits van Griensven, Sharon Mannheimer, James P Hughes, Robert M Grant, Namandjé N Bumpus
Published 2018-01-01

Modeling the Probability of HIV Infection over Time in High-Risk Seronegative Participants Receiving Placebo in Five Randomized Double-Blind Placebo-Controlled HIV Pre-Exposure Pro...

by Maria Garcia-Cremades, Craig W. Hendrix, Priya Jayachandran, Natasha Strydom, Leah Jarlsberg, Robert Grant, Connie L. Celum, Michael Martin, Jared M. Baeten, Jeanne Marrazzo, Peter Anderson, Kachit Choopanya, Suphak Vanichseni, David V. Glidden, Radojka M. Savic
Published 2022-08-01

Tenofovir vaginal film as a potential MPT product against HIV-1 and HSV-2 acquisition: formulation development and preclinical assessment in non-human primates

by Sravan Kumar Patel, Sravan Kumar Patel, Hrushikesh Agashe, Hrushikesh Agashe, Dorothy L. Patton, Yvonne Sweeney, May A. Beamer, Craig W. Hendrix, Sharon L. Hillier, Sharon L. Hillier, Lisa C. Rohan, Lisa C. Rohan, Lisa C. Rohan
Published 2023-08-01

Conceptual Design of a Universal Donor Screening Approach for Vaginal Microbiota Transplant

by Kevin DeLong, Kevin DeLong, Sabrine Bensouda, Sabrine Bensouda, Fareeha Zulfiqar, Fareeha Zulfiqar, Hannah C. Zierden, Hannah C. Zierden, Thuy M. Hoang, Thuy M. Hoang, Alison G. Abraham, Alison G. Abraham, Jenell S. Coleman, Richard A. Cone, Patti E. Gravitt, Patti E. Gravitt, Craig W. Hendrix, Craig W. Hendrix, Edward J. Fuchs, Charlotte A. Gaydos, Charlotte A. Gaydos, Ethel D. Weld, Ethel D. Weld, Ethel D. Weld, Laura M. Ensign, Laura M. Ensign, Laura M. Ensign, Laura M. Ensign, Laura M. Ensign, Laura M. Ensign
Published 2019-08-01

Phase 1 randomized trials to assess safety, pharmacokinetics, and vaginal bleeding associated with use of extended duration dapivirine and levonorgestrel vaginal rings

by Sharon L. Achilles, Clifton W. Kelly, Craig J. Hoesley, Diana L. Blithe, Jill Brown, Barbra A. Richardson, Brid Devlin, Craig W. Hendrix, Samuel M. Poloyac, Mark A. Marzinke, Holly Gundacker, Devika Singh, Jeanna M. Piper, Sherri Johnson, John Steytler, Beatrice A. Chen
Published 2024-01-01

Multispecies Evaluation of a Long-Acting Tenofovir Alafenamide Subdermal Implant for HIV Prophylaxis

by Manjula Gunawardana, Mariana Remedios-Chan, Debbie Sanchez, Simon Webster, Patricia Galvan, Rob Fanter, Amalia E. Castonguay, Paul Webster, John A. Moss, Joseph Kuo, Philippe A. Gallay, Kathleen L. Vincent, Massoud Motamedi, Dana Weinberger, Mark A. Marzinke, Mark A. Marzinke, Craig W. Hendrix, Marc M. Baum
Published 2020-11-01

High PrEP uptake and objective longitudinal adherence among HIV-exposed women with personal or partner plans for pregnancy in rural Uganda: A cohort study.

by Lynn T Matthews, Esther C Atukunda, Moran Owembabazi, Kato Paul Kalyebera, Christina Psaros, Pooja Chitneni, Craig W Hendrix, Mark A Marzinke, Peter L Anderson, Oluwaseyi O Isehunwa, Kathleen E Hurwitz, Kara Bennett, Winnie Muyindike, David R Bangsberg, Jessica E Haberer, Jeanne M Marrazzo, Mwebesa Bosco Bwana
Published 2023-02-01