Editorial: Deciphering the bone marrow microenvironment in hematologic malignancies

by Manja Wobus, Martin Bornhäuser
Published 2023-06-01

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Modulate Hematopoietic Stem and Progenitor Cell Viability and the Expression of Cell Cycle Regulators in an Age-dependent Ma...

by Pascal Fichtel, Malte von Bonin, Robert Kuhnert, Kristin Möbus, Martin Bornhäuser, Martin Bornhäuser, Manja Wobus, Manja Wobus
Published 2022-06-01

Myelodysplastic Syndromes and Metabolism

by Ekaterina Balaian, Manja Wobus, Martin Bornhäuser, Triantafyllos Chavakis, Katja Sockel
Published 2021-10-01

Oxygen tension plays a critical role in the hematopoietic microenvironment in vitro

by Duohui Jing, Manja Wobus, David M. Poitz, Martin Bornhäuser, Gerhard Ehninger, Rainer Ordemann
Published 2012-03-01

OXPHOS supercomplexes as a hallmark of the mitochondrial phenotype of adipogenic differentiated human MSCs.

by Andreas D Hofmann, Mandy Beyer, Udo Krause-Buchholz, Manja Wobus, Martin Bornhäuser, Gerhard Rödel
Published 2012-01-01

Expression of the melanoma cell adhesion molecule in human mesenchymal stromal cells regulates proliferation, differentiation, and maintenance of hematopoietic stem and progenitor...

by Sabine Stopp, Martin Bornhäuser, Fernando Ugarte, Manja Wobus, Matthias Kuhn, Sebastian Brenner, Sebastian Thieme
Published 2013-04-01

Mesenchymal stromal cell-associated migrasomes: a new source of chemoattractant for cells of hematopoietic origin

by Ilker A. Deniz, Jana Karbanová, Manja Wobus, Martin Bornhäuser, Pauline Wimberger, Jan Dominik Kuhlmann, Denis Corbeil
Published 2023-02-01

Human Bone Marrow Stromal Cells: A Reliable, Challenging Tool for In Vitro Osteogenesis and Bone Tissue Engineering Approaches

by Ute Hempel, Katrin Müller, Carolin Preissler, Carolin Noack, Sabine Boxberger, Peter Dieter, Martin Bornhäuser, Manja Wobus
Published 2016-01-01

P705: AZACYTIDINE THERAPY REVERTS MDS-ASSOCIATED CHANGES IN MSC-DERIVED EXTRACELLULAR MATRIX

by Amanpreet Bains, Julia Schulz, Valentina Magno, Toni Radanovic, Sandra Rother, Michael Cross, Xie Xiaofan, Carsten Werner, Manja Wobus, Uwe Platzbecker
Published 2023-08-01

Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions.

by Susann Becker, Elke Wandel, Manja Wobus, Rick Schneider, Salah Amasheh, Doreen Sittig, Christiane Kerner, Ronald Naumann, Joerg Hamann, Gabriela Aust
Published 2010-01-01

Erythropoietin inhibits osteoblast function in myelodysplastic syndromes via the canonical Wnt pathway

by Ekaterina Balaian, Manja Wobus, Heike Weidner, Ulrike Baschant, Maik Stiehler, Gerhard Ehninger, Martin Bornhäuser, Lorenz C Hofbauer, Martina Rauner, Uwe Platzbecker
Published 2018-01-01

Bone marrow mesenchymal stromal cell-derived extracellular matrix displays altered glycosaminoglycan structure and impaired functionality in Myelodysplastic Syndromes

by Amanpreet Kaur Bains, Lena Behrens Wu, Jennifer Rivière, Sandra Rother, Valentina Magno, Jens Friedrichs, Carsten Werner, Martin Bornhäuser, Katharina S. Götze, Michael Cross, Uwe Platzbecker, Manja Wobus
Published 2022-09-01

Bone marrow niche-mimetics modulate HSPC function via integrin signaling

by Martin Kräter, Angela Jacobi, Oliver Otto, Stefanie Tietze, Katrin Müller, David M. Poitz, Sandra Palm, Valentina M. Zinna, Ulrike Biehain, Manja Wobus, Triantafyllos Chavakis, Carsten Werner, Jochen Guck, Martin Bornhauser
Published 2017-05-01

Mesenchymal stromal cells from patients with myelodyplastic syndrome display distinct functional alterations that are modulated by lenalidomide

by Ruben A. Ferrer, Manja Wobus, Catrin List, Rebekka Wehner, Claudia Schönefeldt, Barbara Brocard, Brigitte Mohr, Martina Rauner, Marc Schmitz, Maik Stiehler, Gerhard Ehninger, Lorenz C. Hofbauer, Martin Bornhäuser, Uwe Platzbecker
Published 2013-11-01

MicroRNA-23a mediates post-transcriptional regulation of CXCL12 in bone marrow stromal cells

by Laleh S. Arabanian, Fernando A. Fierro, Friedrich Stölzel, Carolin Heder, David M. Poitz, Ruth H. Strasser, Manja Wobus, Martin Borhäuser, Ruben A. Ferrer, Uwe Platzbecker, Matthias Schieker, Denitsa Docheva, Gerhard Ehninger, Thomas Illmer
Published 2014-06-01

Machine learning assisted real-time deformability cytometry of CD34+ cells allows to identify patients with myelodysplastic syndromes

by Maik Herbig, Angela Jacobi, Manja Wobus, Heike Weidner, Anna Mies, Martin Kräter, Oliver Otto, Christian Thiede, Marie‑Theresa Weickert, Katharina S. Götze, Martina Rauner, Lorenz C. Hofbauer, Martin Bornhäuser, Jochen Guck, Marius Ader, Uwe Platzbecker, Ekaterina Balaian
Published 2022-01-01

Immunomodulatory Properties of Mesenchymal Stromal Cells: An Update

by Luise Müller, Antje Tunger, Antje Tunger, Manja Wobus, Malte von Bonin, Malte von Bonin, Malte von Bonin, Russell Towers, Martin Bornhäuser, Martin Bornhäuser, Martin Bornhäuser, Martin Bornhäuser, Francesco Dazzi, Rebekka Wehner, Rebekka Wehner, Rebekka Wehner, Marc Schmitz, Marc Schmitz, Marc Schmitz, Marc Schmitz
Published 2021-02-01

CD38 promotes hematopoietic stem cell dormancy.

by Liliia Ibneeva, Sumeet Pal Singh, Anupam Sinha, Sema Elif Eski, Rebekka Wehner, Luise Rupp, Iryna Kovtun, Juan Alberto Pérez-Valencia, Alexander Gerbaulet, Susanne Reinhardt, Manja Wobus, Malte von Bonin, Jaime Sancho, Frances Lund, Andreas Dahl, Marc Schmitz, Martin Bornhäuser, Triantafyllos Chavakis, Ben Wielockx, Tatyana Grinenko
Published 2024-02-01

Perturbations of mesenchymal stromal cells after allogeneic hematopoietic cell transplantation predispose for bone marrow graft-versus-host-disease

by Thomas Krüger, Thomas Krüger, Rebekka Wehner, Rebekka Wehner, Rebekka Wehner, Maik Herbig, Maik Herbig, Maik Herbig, Martin Kräter, Martin Kräter, Michael Kramer, Jan Moritz Middeke, Friedrich Stölzel, Catrin List, Katharina Egger-Heidrich, Raphael Teipel, Uta Oelschlägel, Martin Wermke, Martin Wermke, Helena Jambor, Manja Wobus, Johannes Schetelig, Korinna Jöhrens, Torsten Tonn, Torsten Tonn, Julien Subburayalu, Julien Subburayalu, Julien Subburayalu, Julien Subburayalu, Marc Schmitz, Marc Schmitz, Marc Schmitz, Marc Schmitz, Martin Bornhauser, Martin Bornhauser, Martin Bornhauser, Martin Bornhauser, Malte von Bonin, Malte von Bonin
Published 2022-10-01

Biallelic TET2 mutations confer sensitivity to 5′-azacitidine in acute myeloid leukemia

by Friedrich Stölzel, Sarah E. Fordham, Devi Nandana, Wei-Yu Lin, Helen Blair, Claire Elstob, Hayden L. Bell, Brigitte Mohr, Leo Ruhnke, Desiree Kunadt, Claudia Dill, Daniel Allsop, Rachel Piddock, Emmanouela-Niki Soura, Catherine Park, Mohd Fadly, Thahira Rahman, Abrar Alharbi, Manja Wobus, Heidi Altmann, Christoph Röllig, Lisa Wagenführ, Gail L. Jones, Tobias Menne, Graham H. Jackson, Helen J. Marr, Jude Fitzgibbon, Kenan Onel, Manja Meggendorfer, Amber Robinson, Zuzanna Bziuk, Emily Bowes, Olaf Heidenreich, Torsten Haferlach, Sara Villar, Beñat Ariceta, Rosa Ayala Diaz, Steven J. Altschuler, Lani F. Wu, Felipe Prosper, Pau Montesinos, Joaquin Martinez-Lopez, Martin Bornhäuser, James M. Allan
Published 2023-01-01