Novel Hominid-Specific IAPP Isoforms: Potential Biomarkers of Early Alzheimer’s Disease and Inhibitors of Amyloid Formation

by Qing-Rong Liu, Min Zhu, Qinghua Chen, Maja Mustapic, Dimitrios Kapogiannis, Josephine M. Egan
Published 2023-01-01

Lipidomic Analysis of Plasma Extracellular Vesicles Derived from Alzheimer’s Disease Patients

by Marios G. Krokidis, Krishna A. Pucha, Maja Mustapic, Themis P. Exarchos, Panagiotis Vlamos, Dimitrios Kapogiannis
Published 2024-04-01

Empagliflozin Induced Ketosis, Upregulated IGF-1/Insulin Receptors and the Canonical Insulin Signaling Pathway in Neurons, and Decreased the Excitatory Neurotransmitter Glutamate i...

by Konstantinos I. Avgerinos, Roger J. Mullins, Michael Vreones, Maja Mustapic, Qinghua Chen, Denise Melvin, Dimitrios Kapogiannis, Josephine M. Egan
Published 2022-10-01

Anterograde and Retrograde Propagation of Inoculated Human Tau Fibrils and Tau Oligomers in a Non-Transgenic Rat Tauopathy Model

by Lea Langer Horvat, Ena Španić Popovački, Mirjana Babić Leko, Klara Zubčić, Luka Horvat, Maja Mustapić, Patrick R. Hof, Goran Šimić
Published 2023-03-01

Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes

by Maja Mustapic, Erez Eitan, John K. Werner, John K. Werner, Sean T. Berkowitz, Michael P. Lazaropoulos, Joyce Tran, Edward J. Goetzl, Edward J. Goetzl, Dimitrios Kapogiannis
Published 2017-05-01

Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles

by Francesc X. Guix, Grant T. Corbett, Diana J. Cha, Maja Mustapic, Wen Liu, David Mengel, Zhicheng Chen, Elena Aikawa, Tracy Young-Pearse, Dimitrios Kapogiannis, Dennis J. Selkoe, Dominic M. Walsh
Published 2018-02-01

miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients

by Diana J. Cha, David Mengel, David Mengel, David Mengel, Maja Mustapic, Wen Liu, Dennis J. Selkoe, Dimitrios Kapogiannis, Douglas Galasko, Robert A. Rissman, Robert A. Rissman, David A. Bennett, Dominic M. Walsh, Dominic M. Walsh
Published 2019-11-01

Comparative assessment of Alzheimer’s disease-related biomarkers in plasma and neuron-derived extracellular vesicles: a nested case-control study

by Apostolos Manolopoulos, Francheska Delgado-Peraza, Maja Mustapic, Krishna Ananthu Pucha, Carlos Nogueras-Ortiz, Alexander Daskalopoulos, De’Larrian DeAnté Knight, Jeannie-Marie Leoutsakos, Jeannie-Marie Leoutsakos, Esther S. Oh, Esther S. Oh, Constantine G. Lyketsos, Constantine G. Lyketsos, Dimitrios Kapogiannis
Published 2023-09-01

Heritable influence of DBH on adrenergic and renal function: twin and disease studies.

by Dalal N Pasha, Jason T Davis, Fangwen Rao, Yuqing Chen, Gen Wen, Maple M Fung, Manjula Mahata, Kuixing Zhang, Danuta Trzebinska, Maja Mustapic, C Makena Hightower, Michael S Lipkowitz, Ming Ji, Michael G Ziegler, Caroline M Nievergelt, Daniel T O'Connor
Published 2013-01-01

Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer’s disease mouse model

by Carolyn Tallon, Benjamin J. Bell, Medhinee M. Malvankar, Pragney Deme, Carlos Nogueras-Ortiz, Erden Eren, Ajit G. Thomas, Kristen R. Hollinger, Arindom Pal, Maja Mustapic, Meixiang Huang, Kaleem Coleman, Tawnjerae R. Joe, Rana Rais, Norman J. Haughey, Dimitrios Kapogiannis, Barbara S. Slusher
Published 2023-12-01

Mitochondrial RNA in Alzheimer’s Disease Circulating Extracellular Vesicles

by Kyoung Mi Kim, Kyoung Mi Kim, Qiong Meng, Olivia Perez de Acha, Maja Mustapic, Aiwu Cheng, Erden Eren, Gautam Kundu, Yulan Piao, Rachel Munk, William H. Wood, Supriyo De, Ji Heon Noh, Michael Delannoy, Lesley Cheng, Kotb Abdelmohsen, Dimitrios Kapogiannis, Myriam Gorospe
Published 2020-11-01

Single‐extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion Molecule (L1CAM) as a reliable biomarker of neuron‐derived EVs

by Carlos J Nogueras‐Ortiz, Erden Eren, Pamela Yao, Elizabeth Calzada, Christopher Dunn, Olga Volpert, Francheska Delgado‐Peraza, Maja Mustapic, Alexey Lyashkov, F Javier Rubio, Michael Vreones, Lesley Cheng, Yang You, Andrew F Hill, Tsuneya Ikezu, Erez Eitan, Edward J Goetzl, Dimitrios Kapogiannis
Published 2024-06-01