Computer modeling describes gravity-related adaptation in cell cultures.

by Ludmil B Alexandrov, Stoyana Alexandrova, Anny Usheva
Published 2009-12-01

Generating realistic null hypothesis of cancer mutational landscapes using SigProfilerSimulator

by Erik N. Bergstrom, Mark Barnes, Iñigo Martincorena, Ludmil B. Alexandrov
Published 2020-10-01

Nonnegative/Binary matrix factorization with a D-Wave quantum annealer.

by Daniel O'Malley, Velimir V Vesselinov, Boian S Alexandrov, Ludmil B Alexandrov
Published 2018-01-01

Somatic mutational profiles and germline polygenic risk scores in human cancer

by Yuxi Liu, Alexander Gusev, Yujing J. Heng, Ludmil B. Alexandrov, Peter Kraft
Published 2022-02-01

Deciphering Signatures of Mutational Processes Operative in Human Cancer

by Ludmil B. Alexandrov, Serena Nik-Zainal, David C. Wedge, Peter J. Campbell, Michael R. Stratton
Published 2013-01-01

Topography of mutational signatures in human cancer

by Burçak Otlu, Marcos Díaz-Gay, Ian Vermes, Erik N. Bergstrom, Maria Zhivagui, Mark Barnes, Ludmil B. Alexandrov
Published 2023-08-01

SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events

by Erik N. Bergstrom, Mi Ni Huang, Uma Mahto, Mark Barnes, Michael R. Stratton, Steven G. Rozen, Ludmil B. Alexandrov
Published 2019-08-01

Strength of immune selection in tumors varies with sex and age

by Andrea Castro, Rachel Marty Pyke, Xinlian Zhang, Wesley Kurt Thompson, Chi-Ping Day, Ludmil B. Alexandrov, Maurizio Zanetti, Hannah Carter
Published 2020-08-01

Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator

by Azhar Khandekar, Raviteja Vangara, Mark Barnes, Marcos Díaz-Gay, Ammal Abbasi, Erik N. Bergstrom, Christopher D. Steele, Nischalan Pillay, Ludmil B. Alexandrov
Published 2023-08-01

DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer

by Maria Zhivagui, Areebah Hoda, Noelia Valenzuela, Yi-Yu Yeh, Jason Dai, Yudou He, Shuvro P. Nandi, Burcak Otlu, Bennett Van Houten, Ludmil B. Alexandrov
Published 2023-01-01

Arsenic is a potent co-mutagen of ultraviolet light

by Rachel M. Speer, Shuvro P. Nandi, Karen L. Cooper, Xixi Zhou, Hui Yu, Yan Guo, Laurie G. Hudson, Ludmil B. Alexandrov, Ke Jian Liu
Published 2023-12-01

DNA dynamics is likely to be a factor in the genomic nucleotide repeats expansions related to diseases.

by Boian S Alexandrov, Vlad I Valtchinov, Ludmil B Alexandrov, Vladimir Gelev, Yossi Dagon, Jonathan Bock, Isaac S Kohane, Kim Ø Rasmussen, Alan R Bishop, Anny Usheva
Published 2011-01-01

Author Correction: DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer

by Maria Zhivagui, Areebah Hoda, Noelia Valenzuela, Yi-Yu Yeh, Jason Dai, Yudou He, Shuvro P. Nandi, Burcak Otlu, Bennett Van Houten, Ludmil B. Alexandrov
Published 2023-03-01

Correction: DNA Dynamics Is Likely to Be a Factor in the Genomic Nucleotide Repeats Expansions Related to Diseases.

by Boian S. Alexandrov, Vlad I. Valtchinov, Ludmil B. Alexandrov, Vladimir Gelev, Yossi Dagon, Jonathan Bock, Isaac S. Kohane, Kim Ø. Rasmussen, Alan R. Bishop, Anny Usheva
Published 2011-01-01

Binding of nucleoid-associated protein fis to DNA is regulated by DNA breathing dynamics.

by Kristy Nowak-Lovato, Ludmil B Alexandrov, Afsheen Banisadr, Amy L Bauer, Alan R Bishop, Anny Usheva, Fangping Mu, Elizabeth Hong-Geller, Kim Ø Rasmussen, William S Hlavacek, Boian S Alexandrov
Published 2013-01-01

Germline MC1R status influences somatic mutation burden in melanoma

by Carla Daniela Robles-Espinoza, Nicola D. Roberts, Shuyang Chen, Finbarr P. Leacy, Ludmil B. Alexandrov, Natapol Pornputtapong, Ruth Halaban, Michael Krauthammer, Rutao Cui, D. Timothy Bishop, David J. Adams
Published 2016-07-01

Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice

by Yun Rose Li, Kyle D. Halliwill, Cassandra J. Adams, Vivek Iyer, Laura Riva, Rashid Mamunur, Kuang-Yu Jen, Reyno del Rosario, Erik Fredlund, Gillian Hirst, Ludmil B. Alexandrov, David Adams, Allan Balmain
Published 2020-01-01

Mammalian stem cells reprogramming in response to terahertz radiation.

by Jonathan Bock, Yayoi Fukuyo, Sona Kang, M Lisa Phipps, Ludmil B Alexandrov, Kim Ø Rasmussen, Alan R Bishop, Evan D Rosen, Jennifer S Martinez, Hou-Tong Chen, George Rodriguez, Boian S Alexandrov, Anny Usheva
Published 2010-12-01

AI-assisted discovery of an ethnicity-influenced driver of cell transformation in esophageal and gastroesophageal junction adenocarcinomas

by Pradipta Ghosh, Vinicius J. Campos, Daniella T. Vo, Caitlin Guccione, Vanae Goheen-Holland, Courtney Tindle, Guilherme S. Mazzini, Yudou He, Ludmil B. Alexandrov, Scott M. Lippman, Richard R. Gurski, Soumita Das, Rena Yadlapati, Kit Curtius, Debashis Sahoo
Published 2022-09-01

Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1

by Lene Alsøe, Antonio Sarno, Sergio Carracedo, Diana Domanska, Felix Dingler, Lisa Lirussi, Tanima SenGupta, Nuriye Basdag Tekin, Laure Jobert, Ludmil B. Alexandrov, Anastasia Galashevskaya, Cristina Rada, Geir Kjetil Sandve, Torbjørn Rognes, Hans E. Krokan, Hilde Nilsen
Published 2017-08-01