Genetically Engineered Extracellular Vesicles Harboring Transmembrane Scaffolds Exhibit Differences in Their Size, Expression Levels of Specific Surface Markers and Cell-Uptake

by Jiayi Zhang, Annie Brown, Brendan Johnson, David Diebold, Kyle Asano, Gerard Marriott, Biao Lu
Published 2022-11-01

Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing

by Hyatt Balke-Want, Vimal Keerthi, Nikolaos Gkitsas, Andrew G. Mancini, Gavin L. Kurgan, Carley Fowler, Peng Xu, Xikun Liu, Kyle Asano, Sunny Patel, Christopher J. Fisher, Annie K. Brown, Ramya H. Tunuguntla, Shabnum Patel, Elena Sotillo, Crystal L. Mackall, Steven A. Feldman
Published 2023-06-01

275 Inosine endows CAR T cells with features of increased stemness and anti-tumor potency

by Katalin Sandor, Peng Xu, Jing Huang, Steven A Feldman, Nikolaos Gkitsas, Crystal L Mackall, Bence Daniel, Dorota Klysz, Malek Bashti, Elena Sotillo, Ansuman T Satpathy, Carley Fowler, Meena Malipatlolla, Lucille Stuani, Katherine A Freitas, Stefanie Meier, Louai Labanieh, Amaury Leruste, Janette Mata-Alcazar, Vimal Keerthi, Justin A Guerrero, Chris Fisher, Sunny Patel, Kyle Asano, Shabnum Patel, Kara L Davis
Published 2023-11-01