Identification of Myocardial Damage in Systemic Sclerosis: A Nuclear Cardiology Approach

by Kenichi Nakajima, Shinro Matsuo, Minoru Hasegawa, Seigo Kinuya, Kazuhiko Takehara
Published 2010-01-01

The transcriptional cofactor nab2 is induced by tgf-Beta and suppresses fibroblast activation: physiological roles and impaired expression in scleroderma.

by Swati Bhattacharyya, Jun Wei, Denisa S Melichian, Jeffrey Milbrandt, Kazuhiko Takehara, John Varga
Published 2009-10-01

A case of anti‐OJ antibody‐positive polymyositis with marked muscle involvement and interstitial lung disease

by Kyosuke Oishi, Kyoko Shimizu, Kouhei Takehara, Shintaro Maeda, Takashi Matsushita, Toru Yukami, Kazuhiko Takehara, Yasuhito Hamaguchi
Published 2021-02-01

Perspective to precision medicine in scleroderma

by Kazuhiro Komura, Kazuhiro Komura, Koichi Yanaba, Jean-David Bouaziz, Ayumi Yoshizaki, Minoru Hasegawa, John Varga, Kazuhiko Takehara, Takashi Matsushita
Published 2024-01-01

Egr-1 induces a profibrotic injury/repair gene program associated with systemic sclerosis.

by Swati Bhattacharyya, Jennifer L Sargent, Pan Du, Simon Lin, Warren G Tourtellotte, Kazuhiko Takehara, Michael L Whitfield, John Varga
Published 2011-01-01

A case of anti-BP230 antibody-positive bullous pemphigoid receiving DPP-4 inhibitor

by Kaori Sawada, Tomoyo Sawada, Tadahiro Kobayashi, Akiko Fujiki, Takashi Matsushita, Shigeru Kawara, Kentaro Izumi, Wataru Nishie, Hiroshi Shimizu, Kazuhiko Takehara, Yasuhito Hamaguchi
Published 2021-01-01

Clinical Utility of an Enzyme-Linked Immunosorbent Assay for Detecting Anti-Melanoma Differentiation-Associated Gene 5 Autoantibodies.

by Shinji Sato, Akihiro Murakami, Akiko Kuwajima, Kazuhiko Takehara, Tsuneyo Mimori, Atsushi Kawakami, Michiaki Mishima, Takafumi Suda, Mariko Seishima, Manabu Fujimoto, Masataka Kuwana
Published 2016-01-01

Oropharyngeal Dysphagia in Dermatomyositis: Associations with Clinical and Laboratory Features Including Autoantibodies.

by Naoki Mugii, Minoru Hasegawa, Takashi Matsushita, Yasuhito Hamaguchi, Sacihe Oohata, Hirokazu Okita, Tetsutarou Yahata, Fujiko Someya, Katsumi Inoue, Shigeyuki Murono, Manabu Fujimoto, Kazuhiko Takehara
Published 2016-01-01

Serum adhesion molecule levels as prognostic markers in patients with early systemic sclerosis: a multicentre, prospective, observational study.

by Minoru Hasegawa, Yoshihide Asano, Hirahito Endo, Manabu Fujimoto, Daisuke Goto, Hironobu Ihn, Katsumi Inoue, Osamu Ishikawa, Yasushi Kawaguchi, Masataka Kuwana, Fumihide Ogawa, Hiroki Takahashi, Sumiaki Tanaka, Shinichi Sato, Kazuhiko Takehara
Published 2014-01-01

Common and distinct clinical features in adult patients with anti-aminoacyl-tRNA synthetase antibodies: heterogeneity within the syndrome.

by Yasuhito Hamaguchi, Manabu Fujimoto, Takashi Matsushita, Kenzo Kaji, Kazuhiro Komura, Minoru Hasegawa, Masanari Kodera, Eiji Muroi, Keita Fujikawa, Mariko Seishima, Hidehiro Yamada, Ryo Yamada, Shinichi Sato, Kazuhiko Takehara, Masataka Kuwana
Published 2013-01-01

Human Leukocyte Antigen and Systemic Sclerosis in Japanese: The Sign of the Four Independent Protective Alleles, DRB1*13:02, DRB1*14:06, DQB1*03:01, and DPB1*02:01.

by Hiroshi Furukawa, Shomi Oka, Aya Kawasaki, Kota Shimada, Shoji Sugii, Takashi Matsushita, Atsushi Hashimoto, Akiko Komiya, Naoshi Fukui, Kouji Kobayashi, Atsumu Osada, Atsushi Ihata, Yuya Kondo, Tatsuo Nagai, Keigo Setoguchi, Akiko Okamoto, Akira Okamoto, Noriyuki Chiba, Eiichi Suematsu, Hajime Kono, Masao Katayama, Shunsei Hirohata, Takayuki Sumida, Kiyoshi Migita, Minoru Hasegawa, Manabu Fujimoto, Shinichi Sato, Shouhei Nagaoka, Kazuhiko Takehara, Shigeto Tohma, Naoyuki Tsuchiya
Published 2016-01-01

GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region

by Yuki Ishikawa, Nao Tanaka, Yoshihide Asano, Masanari Kodera, Yuichiro Shirai, Mitsuteru Akahoshi, Minoru Hasegawa, Takashi Matsushita, Kazuyoshi Saito, Sei-ichiro Motegi, Hajime Yoshifuji, Ayumi Yoshizaki, Tomohiro Kohmoto, Kae Takagi, Akira Oka, Miho Kanda, Yoshihito Tanaka, Yumi Ito, Kazuhisa Nakano, Hiroshi Kasamatsu, Akira Utsunomiya, Akiko Sekiguchi, Hiroaki Niiro, Masatoshi Jinnin, Katsunari Makino, Takamitsu Makino, Hironobu Ihn, Motohisa Yamamoto, Chisako Suzuki, Hiroki Takahashi, Emi Nishida, Akimichi Morita, Toshiyuki Yamamoto, Manabu Fujimoto, Yuya Kondo, Daisuke Goto, Takayuki Sumida, Naho Ayuzawa, Hidetoshi Yanagida, Tetsuya Horita, Tatsuya Atsumi, Hirahito Endo, Yoshihito Shima, Atsushi Kumanogoh, Jun Hirata, Nao Otomo, Hiroyuki Suetsugu, Yoshinao Koike, Kohei Tomizuka, Soichiro Yoshino, Xiaoxi Liu, Shuji Ito, Keiko Hikino, Akari Suzuki, Yukihide Momozawa, Shiro Ikegawa, Yoshiya Tanaka, Osamu Ishikawa, Kazuhiko Takehara, Takeshi Torii, Shinichi Sato, Yukinori Okada, Tsuneyo Mimori, Fumihiko Matsuda, Koichi Matsuda, Tiffany Amariuta, Issei Imoto, Keitaro Matsuo, Masataka Kuwana, Yasushi Kawaguchi, Koichiro Ohmura, Chikashi Terao
Published 2024-01-01