Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2

by Lan eYe, Behzad eVaramini, Dudley W. Lamming, David M. Sabatini, Joseph A. Baur
Published 2012-09-01

Effect of Interleukin-15 Receptor Alpha Ablation on the Metabolic Responses to Moderate Exercise Simulated by in vivo Isometric Muscle Contractions

by Emanuele Loro, Cholsoon Jang, William J. Quinn, Joseph A. Baur, Zoltan P. Arany, Tejvir S. Khurana
Published 2019-11-01

Supplemental arginine vasopressin during the resuscitation of severe hemorrhagic shock preserves renal mitochondrial function.

by Carrie A Sims, Guan Yuxia, Khushboo Singh, Evan C Werlin, Patrick M Reilly, Joseph A Baur
Published 2017-01-01

An Alternate Splicing Variant of the Human Telomerase Catalytic Subunit Inhibits Telomerase Activity

by Xiaoming Yi, Dennis M. White, Dara L. Aisner, Joseph A. Baur, Woodring E. Wright, Jerry W. Shay
Published 2000-09-01

Use of Optical Redox Imaging to Quantify Alveolar Macrophage Redox State in Infants: Proof of Concept Experiments in a Murine Model and Human Tracheal Aspirates Samples

by He N. Xu, Diego Gonzalves, Jonathan H. Hoffman, Joseph A. Baur, Lin Z. Li, Erik A. Jensen
Published 2024-04-01

Visualizing subcellular changes in the NAD(H) pool size versus redox state using fluorescence lifetime imaging microscopy of NADH

by Angela Song, Nicole Zhao, Diana C. Hilpert, Caroline Perry, Joseph A. Baur, Douglas C. Wallace, Patrick M. Schaefer
Published 2024-04-01

4582 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) DEPLETION MUST BE SEVERE TO INDUCE CARDIAC DYSFUNCTION AND EVENTUAL FAILURE

by Timothy Luongo, Lin Wang, Karthikeyani Chellappa, Melanie R. McReynolds, Daniel P. Kelly, Joshua D. Rabinowitz, Joseph A. Baur
Published 2020-06-01

Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice

by Patrick M. Schaefer, Jessica Huang, Arrienne Butic, Caroline Perry, Tal Yardeni, Wendy Tan, Ryan Morrow, Joseph A. Baur, Douglas C. Wallace
Published 2022-10-01

Loss of FOXO transcription factors in the liver mitigates stress-induced hyperglycemia

by Anna E. Garcia Whitlock, Jamarie Sostre-Colón, Matthew Gavin, Niels D. Martin, Joseph A. Baur, Carrie A. Sims, Paul M. Titchenell
Published 2021-09-01

SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside

by Sarmistha Mukherjee, James Mo, Lauren M. Paolella, Caroline E. Perry, Jade Toth, Mindy M. Hugo, Qingwei Chu, Qian Tong, Karthikeyani Chellappa, Joseph A. Baur
Published 2021-04-01

mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia

by Lauren M. Paolella, Sarmistha Mukherjee, Cassie M. Tran, Bruna Bellaver, Mindy Hugo, Timothy S. Luongo, Swapnil V. Shewale, Wenyun Lu, Karthikeyani Chellappa, Joseph A. Baur
Published 2020-02-01

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

by Antonio Davila, Ling Liu, Karthikeyani Chellappa, Philip Redpath, Eiko Nakamaru-Ogiso, Lauren M Paolella, Zhigang Zhang, Marie E Migaud, Joshua D Rabinowitz, Joseph A Baur
Published 2018-06-01

Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics?

by Nicolai M. Doliba, Qing Liu, Changhong Li, Jie Chen, Pan Chen, Chengyang Liu, David W. Frederick, Joseph A. Baur, Michael J. Bennett, Ali Naji, Franz M. Matschinsky
Published 2015-12-01

Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism

by Elizabeth Nunn, Natasha Jaiswal, Matthew Gavin, Kahealani Uehara, Megan Stefkovich, Karima Drareni, Ryan Calhoun, Michelle Lee, Corey D. Holman, Joseph A. Baur, Patrick Seale, Paul M. Titchenell
Published 2024-02-01

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mic...

by Stefano Tarantini, Marta Noa Valcarcel-Ares, Peter Toth, Andriy Yabluchanskiy, Zsuzsanna Tucsek, Tamas Kiss, Peter Hertelendy, Michael Kinter, Praveen Ballabh, Zoltán Süle, Eszter Farkas, Joseph A. Baur, David A. Sinclair, Anna Csiszar, Zoltan Ungvari
Published 2019-06-01

Primary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling network.

by Zhe Zhang, Mai Tsukikawa, Min Peng, Erzsebet Polyak, Eiko Nakamaru-Ogiso, Julian Ostrovsky, Shana McCormack, Emily Place, Colleen Clarke, Gail Reiner, Elizabeth McCormick, Eric Rappaport, Richard Haas, Joseph A Baur, Marni J Falk
Published 2013-01-01

Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

by Keerthana Gnanapradeepan, Julia I-Ju Leu, Subhasree Basu, Thibaut Barnoud, Madeline Good, Joyce V Lee, William J Quinn, Che-Pei Kung, Rexford Ahima, Joseph A Baur, Kathryn E Wellen, Qin Liu, Zachary T Schug, Donna L George, Maureen E Murphy
Published 2020-11-01

Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes.

by Prasanna M Chandramouleeswaran, Manti Guha, Masataka Shimonosono, Kelly A Whelan, Hisatsugu Maekawa, Uma M Sachdeva, Gordon Ruthel, Sarmistha Mukherjee, Noah Engel, Michael V Gonzalez, James Garifallou, Shinya Ohashi, Andres J Klein-Szanto, Clementina A Mesaros, Ian A Blair, Renata Pellegrino da Silva, Hakon Hakonarson, Eishi Noguchi, Joseph A Baur, Hiroshi Nakagawa
Published 2020-01-01

What is new for an old molecule? Systematic review and recommendations on the use of resveratrol.

by Ole Vang, Nihal Ahmad, Clifton A Baile, Joseph A Baur, Karen Brown, Anna Csiszar, Dipak K Das, Dominique Delmas, Carmem Gottfried, Hung-Yun Lin, Qing-Yong Ma, Partha Mukhopadhyay, Namasivayam Nalini, John M Pezzuto, Tristan Richard, Yogeshwer Shukla, Young-Joon Surh, Thomas Szekeres, Tomasz Szkudelski, Thomas Walle, Joseph M Wu
Published 2011-01-01

Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo

by Peter J. Siska, Jing Jiao, Carina Matos, Katrin Singer, Raffaela S. Berger, Katja Dettmer, Peter J. Oefner, Michelle D. Cully, Zhonglin Wang, William J. QuinnIII, Kristen N. Oliff, Benjamin J. Wilkins, Lanette M. Christensen, Liqing Wang, Wayne W. Hancock, Joseph A. Baur, Matthew H. Levine, Ines Ugele, Roman Mayr, Kathrin Renner, Liang Zhou, Marina Kreutz, Ulf H. Beier
Published 2021-12-01