Cell-type- and region-specific restriction of neurotropic flavivirus infection by viperin

by Richard Lindqvist, Chaitanya Kurhade, Jonathan D. Gilthorpe, Anna K. Överby
Published 2018-03-01

Extracellular histone H1 is neurotoxic and drives a pro-inflammatory response in microglia [v1; ref status: indexed, http://f1000r.es/18z]

by Jonathan D Gilthorpe, Fazal Oozeer, Julia Nash, Margarita Calvo, David LH Bennett, Andrew Lumsden, Adrian Pini
Published 2013-07-01

Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients.

by Isil Keskin, Elin Forsgren, Dale J Lange, Markus Weber, Anna Birve, Matthis Synofzik, Jonathan D Gilthorpe, Peter M Andersen, Stefan L Marklund
Published 2016-01-01

Aggregate-selective antibody attenuates seeded aggregation but not spontaneously evolving disease in SOD1 ALS model mice

by Manuela Lehmann, Matthew Marklund, Anna-Lena Bolender, Elaheh E. Bidhendi, Per Zetterström, Peter M. Andersen, Thomas Brännström, Stefan L. Marklund, Jonathan D. Gilthorpe, Ulrika Nordström
Published 2020-09-01

Intense inflammation and nerve damage in early multiple sclerosis subsides at older age: a reflection by cerebrospinal fluid biomarkers.

by Mohsen Khademi, Ann M Dring, Jonathan D Gilthorpe, Anna Wuolikainen, Faiez Al Nimer, Robert A Harris, Magnus Andersson, Lou Brundin, Fredrik Piehl, Tomas Olsson, Anders Svenningsson
Published 2013-01-01

ApoE Isoforms Inhibit Amyloid Aggregation of Proinflammatory Protein S100A9

by Shamasree Ghosh, Shanmugam Tamilselvi, Chloe Williams, Sanduni W. Jayaweera, Igor A. Iashchishyn, Darius Šulskis, Jonathan D. Gilthorpe, Anders Olofsson, Vytautas Smirnovas, Željko M. Svedružić, Ludmilla A. Morozova-Roche
Published 2024-02-01

Alteration of Mitochondrial Integrity as Upstream Event in the Pathophysiology of SOD1-ALS

by René Günther, Arun Pal, Chloe Williams, Vitaly L. Zimyanin, Maria Liehr, Cläre von Neubeck, Mechthild Krause, Mrudula G. Parab, Susanne Petri, Norman Kalmbach, Stefan L. Marklund, Jared Sterneckert, Peter Munch Andersen, Florian Wegner, Jonathan D. Gilthorpe, Andreas Hermann
Published 2022-04-01

Dissecting the genetic landscape of GPCR signaling through phenotypic profiling in C. elegans

by Longjun Pu, Jing Wang, Qiongxuan Lu, Lars Nilsson, Alison Philbrook, Anjali Pandey, Lina Zhao, Robin van Schendel, Alan Koh, Tanara V. Peres, Weheliye H. Hashi, Si Lhyam Myint, Chloe Williams, Jonathan D. Gilthorpe, Sun Nyunt Wai, Andre Brown, Marcel Tijsterman, Piali Sengupta, Johan Henriksson, Changchun Chen
Published 2023-12-01

Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming

by Ioannis S. Pateras, Chloe Williams, Despoina D. Gianniou, Aggelos T. Margetis, Margaritis Avgeris, Pantelis Rousakis, Aigli-Ioanna Legaki, Peter Mirtschink, Wei Zhang, Konstantina Panoutsopoulou, Anastasios D. Delis, Stamatis N. Pagakis, Wei Tang, Stefan Ambs, Ulrika Warpman Berglund, Thomas Helleday, Anastasia Varvarigou, Antonios Chatzigeorgiou, Anders Nordström, Ourania E. Tsitsilonis, Ioannis P. Trougakos, Jonathan D. Gilthorpe, Teresa Frisan
Published 2023-03-01