Differential Dose- and Tissue-Dependent Effects of foxo on Aging, Metabolic and Proteostatic Pathways

by Maria S. Manola, Sentiljana Gumeni, Ioannis P. Trougakos
Published 2021-12-01

Molecular chaperones and proteostasis regulation during redox imbalance

by Katerina Niforou, Christina Cheimonidou, Ioannis P. Trougakos
Published 2014-01-01

Expression profiling meta-analysis of ACE2 and TMPRSS2, the putative anti-inflammatory receptor and priming protease of SARS-CoV-2 in human cells, and identification of putative mo...

by Eirini Gkogkou, Grigoris Barnasas, Konstantinos Vougas, Ioannis P. Trougakos
Published 2020-09-01

Apoptosis Deregulation and the Development of Cancer Multi-Drug Resistance

by Christiana M. Neophytou, Ioannis P. Trougakos, Nuray Erin, Panagiotis Papageorgis
Published 2021-08-01

Proteome Stability as a Key Factor of Genome Integrity

by Sentiljana Gumeni, Zoi Evangelakou, Vassilis G. Gorgoulis, Ioannis P. Trougakos
Published 2017-09-01

Nrf2 activation induces mitophagy and reverses Parkin/Pink1 knock down-mediated neuronal and muscle degeneration phenotypes

by Sentiljana Gumeni, Eleni-Dimitra Papanagnou, Maria S. Manola, Ioannis P. Trougakos
Published 2021-07-01

Sustained Nrf2 Overexpression-Induced Metabolic Deregulation Can Be Attenuated by Modulating Insulin/Insulin-like Growth Factor Signaling

by Sentiljana Gumeni, Maria Lamprou, Zoi Evangelakou, Maria S. Manola, Ioannis P. Trougakos
Published 2023-11-01

Functional wiring of proteostatic and mitostatic modules ensures transient organismal survival during imbalanced mitochondrial dynamics

by Sentiljana Gumeni, Zoi Evangelakou, Eleni N. Tsakiri, Luca Scorrano, Ioannis P. Trougakos
Published 2019-06-01

Apolipoprotein J/Clusterin is a novel structural component of human erythrocytes and a biomarker of cellular stress and senescence.

by Marianna H Antonelou, Anastasios G Kriebardis, Konstantinos E Stamoulis, Ioannis P Trougakos, Issidora S Papassideri
Published 2011-01-01

Apolipoprotein J/clusterin in human erythrocytes is involved in the molecular process of defected material disposal during vesiculation.

by Marianna H Antonelou, Anastasios G Kriebardis, Konstantinos E Stamoulis, Ioannis P Trougakos, Issidora S Papassideri
Published 2011-01-01

Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts

by Aimilia D. Sklirou, Marianna Ralli, Maria Dominguez, Issidora Papassideri, Alexios-Leandros Skaltsounis, Ioannis P. Trougakos
Published 2015-08-01

Terrestrial Microorganisms: Cell Factories of Bioactive Molecules with Skin Protecting Applications

by Laure-Anne Peyrat, Nikolaos Tsafantakis, Katerina Georgousaki, Jamal Ouazzani, Olga Genilloud, Ioannis P. Trougakos, Nikolas Fokialakis
Published 2019-05-01

Bromamine T (BAT) Exerts Stronger Anti-Cancer Properties than Taurine (Tau)

by Stella Baliou, Maria Goulielmaki, Petros Ioannou, Christina Cheimonidi, Ioannis P. Trougakos, Markus Nagl, Anthony M. Kyriakopoulos, Vassilis Zoumpourlis
Published 2021-01-01

High mRNA Expression Levels of Heat Shock Protein Family B Member 2 (<i>HSPB2</i>) Are Associated with Breast Cancer Patients’ Relapse and Poor Survival

by Aimilia D. Sklirou, Despoina D. Gianniou, Paraskevi Karousi, Christina Cheimonidi, Georgia Papachristopoulou, Christos K. Kontos, Andreas Scorilas, Ioannis P. Trougakos
Published 2022-08-01

Biological Evaluation and In Silico Study of Benzoic Acid Derivatives from <i>Bjerkandera adusta</i> Targeting Proteostasis Network Modules

by Katerina Georgousaki, Nikolaos Tsafantakis, Sentiljana Gumeni, George Lambrinidis, Victor González-Menéndez, Jose R. Tormo, Olga Genilloud, Ioannis P. Trougakos, Nikolas Fokialakis
Published 2020-02-01

Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical Relevance

by Raquel Alves, Ana Cristina Gonçalves, Sergio Rutella, António M. Almeida, Javier De Las Rivas, Ioannis P. Trougakos, Ana Bela Sarmento Ribeiro
Published 2021-09-01

Evaluation of the Small Heat Shock Protein Family Members <i>HSPB2</i> and <i>HSPB3</i> in Bladder Cancer Prognosis and Progression

by Despoina D. Gianniou, Aimilia D. Sklirou, Maria-Alexandra Papadimitriou, Katerina-Marina Pilala, Konstantinos Stravodimos, Margaritis Avgeris, Andreas Scorilas, Ioannis P. Trougakos
Published 2023-01-01

Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications

by Ioannis P. Trougakos, Kimon Stamatelopoulos, Evangelos Terpos, Ourania E. Tsitsilonis, Evmorfia Aivalioti, Dimitrios Paraskevis, Efstathios Kastritis, George N. Pavlakis, Meletios A. Dimopoulos
Published 2021-01-01

Third Dose of the BNT162b2 Vaccine Results in Sustained High Levels of Neutralizing Antibodies Against SARS-CoV-2 at 6 Months Following Vaccination in Healthy Individuals

by Ioannis Ntanasis-Stathopoulos, Vangelis Karalis, Aimilia D. Sklirou, Maria Gavriatopoulou, Harry Alexopoulos, Panagiotis Malandrakis, Ioannis P. Trougakos, Meletios A. Dimopoulos, Evangelos Terpos
Published 2022-07-01

Isolation of an Extract from the Soft Coral Symbiotic Microorganism <i>Salinispora arenicola</i> Exerting Cytoprotective and Anti-Aging Effects

by Xanthippi P. Louka, Aimilia D. Sklirou, Géraldine Le Goff, Philippe Lopes, Eleni-Dimitra Papanagnou, Maria S. Manola, Yehuda Benayahu, Jamal Ouazzani, Ioannis P. Trougakos
Published 2021-12-01