All PI3Kinase signaling is not mTOR: Dissecting mTOR-dependent and independent signaling pathways in T cells

by Christopher Jordan Gamper, Jonathan D. Powell
Published 2012-10-01

A2aR antagonists: Next generation checkpoint blockade for cancer immunotherapy

by Robert D. Leone, Ying-Chun Lo, Jonathan D. Powell
Published 2015-01-01

Egr3 induces a Th17 response by promoting the development of γδ T cells.

by Rose M Parkinson, Samuel L Collins, Maureen R Horton, Jonathan D Powell
Published 2014-01-01

Manipulation of Metabolic Pathways and Its Consequences for Anti-Tumor Immunity: A Clinical Perspective

by Huang-Yu Yang, Chao-Yi Wu, Jonathan D. Powell, Kun-Lin Lu
Published 2020-06-01

Cellular size as a means of tracking mTOR activity and cell fate of CD4+ T cells upon antigen recognition.

by Kristen N Pollizzi, Adam T Waickman, Chirag H Patel, Im Hong Sun, Jonathan D Powell
Published 2015-01-01

Pulmonary vaccination as a novel treatment for lung fibrosis.

by Samuel L Collins, Yee Chan-Li, Robert W Hallowell, Jonathan D Powell, Maureen R Horton
Published 2012-01-01

Regulation of CD4⁺ and CD8⁺ effector responses by Sprouty-1.

by Sam Collins, Adam Waickman, Albert Basson, Abraham Kupfer, Jonathan D Licht, Maureen R Horton, Jonathan D Powell
Published 2012-01-01

Targeting Metabolism as a Platform for Inducing Allograft Tolerance in the Absence of Long-Term Immunosuppression

by Chih-Hsien Cheng, Chih-Hsien Cheng, Chih-Hsien Cheng, Chen-Fang Lee, Chen-Fang Lee, Chen-Fang Lee, Byoung Chol Oh, Georg J. Furtmüller, Chirag H. Patel, Chirag H. Patel, Gerald Brandacher, Jonathan D. Powell, Jonathan D. Powell
Published 2020-04-01

Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased γδ T Cells.

by Christine L Vigeland, Samuel L Collins, Yee Chan-Li, Andrew H Hughes, Min-Hee Oh, Jonathan D Powell, Maureen R Horton
Published 2016-01-01

GOT1 regulates CD8+ effector and memory T cell generation

by Wei Xu, Chirag H. Patel, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Rachel S. Helms, Jiayu Wen, Jonathan D. Powell
Published 2023-01-01

mTORC2 Signaling Selectively Regulates the Generation and Function of Tissue-Resident Peritoneal Macrophages

by Min-Hee Oh, Samuel L. Collins, Im-Hong Sun, Ada J. Tam, Chirag H. Patel, Matthew L. Arwood, Yee Chan-Li, Jonathan D. Powell, Maureen R. Horton
Published 2017-09-01

Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis

by Sadiya Parveen, Jessica Shen, Shichun Lun, Liang Zhao, Jesse Alt, Benjamin Koleske, Robert D. Leone, Rana Rais, Jonathan D. Powell, John R. Murphy, Barbara S. Slusher, William R. Bishai
Published 2023-11-01

TSC2 S1365A mutation potently regulates CD8+ T cell function and differentiation and improves adoptive cellular cancer therapy

by Chirag H. Patel, Yi Dong, Navid Koleini, Xiaoxu Wang, Brittany L. Dunkerly-Eyring, Jiayu Wen, Mark J. Ranek, Laura M. Bartle, Daniel B. Henderson, Jason Sagert, David A. Kass, Jonathan D. Powell
Published 2023-11-01

Preventing Allograft Rejection by Targeting Immune Metabolism

by Chen-Fang Lee, Ying-Chun Lo, Chih-Hsien Cheng, Georg J. Furtmüller, Byoungchol Oh, Vinicius Andrade-Oliveira, Ajit G. Thomas, Caitlyn E. Bowman, Barbara S. Slusher, Michael J. Wolfgang, Gerald Brandacher, Jonathan D. Powell
Published 2015-10-01

Sirolimus-eluting airway stent reduces profibrotic Th17 cells and inhibits laryngotracheal stenosis

by Kevin M. Motz, Ioan A. Lina, Idris Samad, Michael K. Murphy, Madhavi Duvvuri, Ruth J. Davis, Alexander Gelbard, Liam Chung, Yee Chan-Li, Samuel Collins, Jonathan D. Powell, Jennifer H. Elisseeff, Maureen R. Horton, Alexander T. Hillel
Published 2023-06-01

Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer

by Alok Kumar Singh, Monali Praharaj, Kara A. Lombardo, Takahiro Yoshida, Andres Matoso, Alex S. Baras, Liang Zhao, Geetha Srikrishna, Joy Huang, Pankaj Prasad, Jonathan D. Powell, Max Kates, David McConkey, Drew M. Pardoll, William R. Bishai, Trinity J. Bivalacqua
Published 2022-02-01

Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice

by Alvaro A. Ordonez, C. Korin Bullen, Andres F. Villabona-Rueda, Elizabeth A. Thompson, Mitchell L. Turner, Vanessa F. Merino, Yu Yan, John Kim, Stephanie L. Davis, Oliver Komm, Jonathan D. Powell, Franco R. D’Alessio, Robert H. Yolken, Sanjay K. Jain, Lorraine Jones-Brando
Published 2022-03-01

Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance

by Mayura V. Wagle, Stephin J. Vervoort, Madison J. Kelly, Willem Van Der Byl, Timothy J. Peters, Ben P. Martin, Luciano G. Martelotto, Simone Nüssing, Kelly M. Ramsbottom, James R. Torpy, Deborah Knight, Sinead Reading, Kevin Thia, Lisa A. Miosge, Debbie R. Howard, Renee Gloury, Sarah S. Gabriel, Daniel T. Utzschneider, Jane Oliaro, Jonathan D. Powell, Fabio Luciani, Joseph A. Trapani, Ricky W. Johnstone, Axel Kallies, Christopher C. Goodnow, Ian A. Parish
Published 2021-05-01