Calcineurin-inhibitor free immunosuppression after lung transplantation - a single center case-control study in 51 patients converted to Mechanistic Target of Rapamycin (mTOR) inhi...

by Jens Gottlieb, Bettina Fischer, Jonas C Schupp, Heiko Golpon
Published 2023-01-01

Bronchoalveolar Lavage Fluid Reflects a TH1-CD21low B-Cell Interaction in CVID-Related Interstitial Lung Disease

by David Friedmann, David Friedmann, David Friedmann, Susanne Unger, Susanne Unger, Susanne Unger, Baerbel Keller, Baerbel Keller, Mirzokhid Rakhmanov, Mirzokhid Rakhmanov, Mirzokhid Rakhmanov, Sigune Goldacker, Sigune Goldacker, Gernot Zissel, Björn C. Frye, Jonas C. Schupp, Jonas C. Schupp, Antje Prasse, Antje Prasse, Klaus Warnatz, Klaus Warnatz
Published 2021-02-01

Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data

by Edward P. Manning, Edward P. Manning, Abhay B. Ramachandra, Jonas C. Schupp, Jonas C. Schupp, Cristina Cavinato, Micha Sam Brickman Raredon, Micha Sam Brickman Raredon, Micha Sam Brickman Raredon, Thomas Bärnthaler, Thomas Bärnthaler, Carlos Cosme, Inderjit Singh, George Tellides, George Tellides, George Tellides, Naftali Kaminski, Jay D. Humphrey, Jay D. Humphrey
Published 2021-09-01

Long noncoding RNA TINCR is a novel regulator of human bronchial epithelial cell differentiation state

by Norihito Omote, Koji Sakamoto, Qin Li, Jonas C. Schupp, Taylor Adams, Farida Ahangari, Maurizio Chioccioli, Giuseppe DeIuliis, Naozumi Hashimoto, Yoshinori Hasegawa, Naftali Kaminski
Published 2021-02-01

Platform Effects on Regeneration by Pulmonary Basal Cells as Evaluated by Single-Cell RNA Sequencing

by Allison M. Greaney, Taylor S. Adams, Micha Sam Brickman Raredon, Elise Gubbins, Jonas C. Schupp, Alexander J. Engler, Mahboobe Ghaedi, Yifan Yuan, Naftali Kaminski, Laura E. Niklason
Published 2020-03-01

iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects

by Yunqing Liu, Jiayi Zhao, Taylor S. Adams, Ningya Wang, Jonas C. Schupp, Weimiao Wu, John E. McDonough, Geoffrey L. Chupp, Naftali Kaminski, Zuoheng Wang, Xiting Yan
Published 2023-08-01

Correction: iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects

by Yunqing Liu, Jiayi Zhao, Taylor S. Adams, Ningya Wang, Jonas C. Schupp, Weimiao Wu, John E. McDonough, Geoffrey L. Chupp, Naftali Kaminski, Zuoheng Wang, Xiting Yan
Published 2023-10-01

Genetic and geographic influence on phenotypic variation in European sarcoidosis patients

by Sandra Freitag-Wolf, Jonas C. Schupp, Jonas C. Schupp, Jonas C. Schupp, Björn C. Frye, Annegret Fischer, Raihanatul Anwar, Robert Kieszko, Violeta Mihailović-Vučinić, Janusz Milanowski, Dragana Jovanovic, Gernot Zissel, Elena Bargagli, Paola Rottoli, Dragos Bumbacea, René Jonkers, Ling-Pei Ho, Karoline I. Gaede, Anna Dubaniewicz, Ben G. Marshall, Andreas Günther, Martin Petrek, Michael P. Keane, Sigridur O. Haraldsdottir, Francesco Bonella, Christian Grah, Tatjana Peroš-Golubičić, Zamir Kadija, Stefan Pabst, Christian Grohé, János Strausz, Martina Safrankova, Ann Millar, Jiří Homolka, Wim A. Wuyts, Lisa G. Spencer, Michael Pfeifer, Dominique Valeyre, Venerino Poletti, Hubertus Wirtz, Antje Prasse, Antje Prasse, Stefan Schreiber, Stefan Schreiber, Astrid Dempfle, Joachim Müller-Quernheim
Published 2023-08-01

Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma

by Ailu Chen, Maria P. Diaz-Soto, Miguel F. Sanmamed, Taylor Adams, Jonas C. Schupp, Amolika Gupta, Clemente Britto, Maor Sauler, Xiting Yan, Qing Liu, Gustavo Nino, Charles S. Dela Cruz, Geoffrey L. Chupp, Jose L. Gomez
Published 2021-04-01

A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds

by Yifan Yuan, Yifan Yuan, Katherine L. Leiby, Katherine L. Leiby, Katherine L. Leiby, Allison M. Greaney, Allison M. Greaney, Micha Sam Brickman Raredon, Micha Sam Brickman Raredon, Micha Sam Brickman Raredon, Hong Qian, Hong Qian, Jonas C. Schupp, Jonas C. Schupp, Alexander J. Engler, Alexander J. Engler, Pavlina Baevova, Pavlina Baevova, Taylor S. Adams, Mehmet H. Kural, Mehmet H. Kural, Juan Wang, Juan Wang, Tomohiro Obata, Tomohiro Obata, Mervin C. Yoder, Naftali Kaminski, Laura E. Niklason, Laura E. Niklason, Laura E. Niklason
Published 2021-11-01

Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis

by Tatsuya Tsukui, Kai-Hui Sun, Joseph B. Wetter, John R. Wilson-Kanamori, Lisa A. Hazelwood, Neil C. Henderson, Taylor S. Adams, Jonas C. Schupp, Sergio D. Poli, Ivan O. Rosas, Naftali Kaminski, Michael A. Matthay, Paul J. Wolters, Dean Sheppard
Published 2020-04-01

FK506-Binding Protein 11 Is a Novel Plasma Cell-Specific Antibody Folding Catalyst with Increased Expression in Idiopathic Pulmonary Fibrosis

by Stefan Preisendörfer, Yoshihiro Ishikawa, Elisabeth Hennen, Stephan Winklmeier, Jonas C. Schupp, Larissa Knüppel, Isis E. Fernandez, Leonhard Binzenhöfer, Andrew Flatley, Brenda M. Juan-Guardela, Clemens Ruppert, Andreas Guenther, Marion Frankenberger, Rudolf A. Hatz, Nikolaus Kneidinger, Jürgen Behr, Regina Feederle, Aloys Schepers, Anne Hilgendorff, Naftali Kaminski, Edgar Meinl, Hans Peter Bächinger, Oliver Eickelberg, Claudia A. Staab-Weijnitz
Published 2022-04-01

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

by Linh T. Bui, Nichelle I. Winters, Mei-I Chung, Chitra Joseph, Austin J. Gutierrez, Arun C. Habermann, Taylor S. Adams, Jonas C. Schupp, Sergio Poli, Lance M. Peter, Chase J. Taylor, Jessica B. Blackburn, Bradley W. Richmond, Andrew G. Nicholson, Doris Rassl, William A. Wallace, Ivan O. Rosas, R. Gisli Jenkins, Naftali Kaminski, Jonathan A. Kropski, Nicholas E. Banovich, Human Cell Atlas Lung Biological Network
Published 2021-07-01

microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis

by Farida Ahangari, Nathan L. Price, Shipra Malik, Maurizio Chioccioli, Thomas Bärnthaler, Taylor S. Adams, Jooyoung Kim, Sai Pallavi Pradeep, Shuizi Ding, Carlos Cosmos Jr., Kadi-Ann S. Rose, John E. McDonough, Nachelle R. Aurelien, Gabriel Ibarra, Norihito Omote, Jonas C. Schupp, Giuseppe DeIuliis, Julian A. Villalba Nunez, Lokesh Sharma, Changwan Ryu, Charles S. Dela Cruz, Xinran Liu, Antje Prasse, Ivan Rosas, Raman Bahal, Carlos Fernández-Hernando, Naftali Kaminski
Published 2023-02-01

Characterization of the COPD alveolar niche using single-cell RNA sequencing

by Maor Sauler, John E. McDonough, Taylor S. Adams, Neeharika Kothapalli, Thomas Barnthaler, Rhiannon B. Werder, Jonas C. Schupp, Jessica Nouws, Matthew J. Robertson, Cristian Coarfa, Tao Yang, Maurizio Chioccioli, Norihito Omote, Carlos Cosme, Sergio Poli, Ehab A. Ayaub, Sarah G. Chu, Klaus H. Jensen, Jose L. Gomez, Clemente J. Britto, Micha Sam B. Raredon, Laura E. Niklason, Andrew A. Wilson, Pascal N. Timshel, Naftali Kaminski, Ivan O. Rosas
Published 2022-01-01

Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19

by Avraham Unterman, Tomokazu S. Sumida, Nima Nouri, Xiting Yan, Amy Y. Zhao, Victor Gasque, Jonas C. Schupp, Hiromitsu Asashima, Yunqing Liu, Carlos Cosme, Wenxuan Deng, Ming Chen, Micha Sam Brickman Raredon, Kenneth B. Hoehn, Guilin Wang, Zuoheng Wang, Giuseppe DeIuliis, Neal G. Ravindra, Ningshan Li, Christopher Castaldi, Patrick Wong, John Fournier, Santos Bermejo, Lokesh Sharma, Arnau Casanovas-Massana, Chantal B. F. Vogels, Anne L. Wyllie, Nathan D. Grubaugh, Anthony Melillo, Hailong Meng, Yan Stein, Maksym Minasyan, Subhasis Mohanty, William E. Ruff, Inessa Cohen, Khadir Raddassi, The Yale IMPACT Research Team, Laura E. Niklason, Albert I. Ko, Ruth R. Montgomery, Shelli F. Farhadian, Akiko Iwasaki, Albert C. Shaw, David van Dijk, Hongyu Zhao, Steven H. Kleinstein, David A. Hafler, Naftali Kaminski, Charles S. Dela Cruz
Published 2022-01-01