In-Silico Analysis of Monoclonal Antibodies against SARS-CoV-2 Omicron

by Ye-Fan Hu, Jing-Chu Hu, Hin Chu, Thomas Yau, Bao-Zhong Zhang, Jian-Dong Huang
Published 2022-02-01

Computation of Antigenicity Predicts SARS-CoV-2 Vaccine Breakthrough Variants

by Ye-Fan Hu, Ye-Fan Hu, Jing-Chu Hu, Hua-Rui Gong, Antoine Danchin, Antoine Danchin, Ren Sun, Hin Chu, Ivan Fan-Ngai Hung, Kwok Yung Yuen, Kelvin Kai-Wang To, Bao-Zhong Zhang, Thomas Yau, Jian-Dong Huang, Jian-Dong Huang, Jian-Dong Huang
Published 2022-03-01

The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans.

by Xiao Na Wang, Ze Song Li, Yu Ren, Tao Jiang, Ya Qing Wang, Min Chen, Jun Zhang, Jian Xiu Hao, Yan Bo Wang, Ri Na Sha, Yi Huang, Xiao Liu, Jing Chu Hu, Guang Qing Sun, Hong Gang Li, Cheng Liang Xiong, Jun Xie, Zhi Mao Jiang, Zhi Ming Cai, Jun Wang, Jian Wang, Vicki Huff, Yao Ting Gui, Fei Gao
Published 2013-01-01

Bacillus Calmette-Guérin–induced trained immunity protects against SARS-CoV-2 challenge in K18-hACE2 mice

by Bao-Zhong Zhang, Huiping Shuai, Hua-Rui Gong, Jing-Chu Hu, Bingpeng Yan, Terrence Tsz-Tai Yuen, Ye-Fan Hu, Chaemin Yoon, Xiao-Lei Wang, Yuxin Hou, Xuansheng Lin, Xiner Huang, Renhao Li, Yee Man Au-Yeung, Wenjun Li, Bingjie Hu, Yue Chai, Ming Yue, Jian-Piao Cai, Guang Sheng Ling, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Jasper Fuk-Woo Chan, Jian-Dong Huang, Hin Chu
Published 2022-06-01

The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA.1, BA.2, and BA.5Research in context

by Huiping Shuai, Jasper Fuk-Woo Chan, Bingjie Hu, Yue Chai, Chaemin Yoon, Huan Liu, Yuanchen Liu, Jialu Shi, Tianrenzheng Zhu, Jing-Chu Hu, Ye-fan Hu, Yuxin Hou, Xiner Huang, Terrence Tsz-Tai Yuen, Yang Wang, Jinjin Zhang, Yao Xia, Lin-Lei Chen, Jian-Piao Cai, Anna Jinxia Zhang, Shuofeng Yuan, Jie Zhou, Bao-Zhong Zhang, Jian-Dong Huang, Kwok-Yung Yuen, Kelvin Kai-Wang To, Hin Chu
Published 2023-09-01

A novel linker-immunodominant site (LIS) vaccine targeting the SARS-CoV-2 spike protein protects against severe COVID-19 in Syrian hamsters

by Bao-Zhong Zhang, Xiaolei Wang, Shuofeng Yuan, Wenjun Li, Ying Dou, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Jian-Piao Cai, Kenn KaHeng Chik, Kaiming Tang, Chris Chun-Yiu Chan, Ye-Fan Hu, Jing-Chu Hu, Smaranda Ruxandra Badea, Hua-Rui Gong, Xuansheng Lin, Hin Chu, Xuechen Li, Kelvin Kai-Wang To, Li Liu, Zhiwei Chen, Ivan Fan-Ngai Hung, Kwok Yung Yuen, Jasper Fuk-Woo Chan, Jian-Dong Huang
Published 2021-01-01

Divergent trajectory of replication and intrinsic pathogenicity of SARS-CoV-2 Omicron post-BA.2/5 subvariants in the upper and lower respiratory tractResearch in context

by Bingjie Hu, Jasper Fuk-Woo Chan, Yuanchen Liu, Huan Liu, Yan-Xia Chen, Huiping Shuai, Ye-Fan Hu, Madeline Hartnoll, Li Chen, Yao Xia, Jing-Chu Hu, Terrence Tsz-Tai Yuen, Chaemin Yoon, Yuxin Hou, Xiner Huang, Yue Chai, Tianrenzheng Zhu, Jialu Shi, Yang Wang, Yixin He, Jian-Piao Cai, Jie Zhou, Shuofeng Yuan, Jinxia Zhang, Jian-Dong Huang, Kwok-Yung Yuen, Kelvin Kai-Wang To, Bao-Zhong Zhang, Hin Chu
Published 2024-01-01

Emerging SARS-CoV-2 variants expand species tropism to murines

by Huiping Shuai, Jasper Fuk-Woo Chan, Terrence Tsz-Tai Yuen, Chaemin Yoon, Jing-Chu Hu, Lei Wen, Bingjie Hu, Dong Yang, Yixin Wang, Yuxin Hou, Xiner Huang, Yue Chai, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Lu Lu, Rui-Qi Zhang, Wan-Mui Chan, Jonathan Daniel Ip, Allen Wing-Ho Chu, Ye-Fan Hu, Jian-Piao Cai, Kwok-Hung Chan, Jie Zhou, Siddharth Sridhar, Bao-Zhong Zhang, Shuofeng Yuan, Anna Jinxia Zhang, Jian-Dong Huang, Kelvin Kai-Wang To, Kwok-Yung Yuen, Hin Chu
Published 2021-11-01