Putative modulation of the gut microbiome by probiotics enhances preference for novelty in a preliminary double-blind placebo-controlled study in ferrets

by Supritha Dugyala, Travis S. Ptacek, Jeremy M. Simon, Yuhui Li, Flavio Fröhlich
Published 2020-05-01

An EZH2-NF-κB regulatory axis drives expression of pro-oncogenic gene signatures in triple negative breast cancer

by Gabrielle J. Dardis, Jun Wang, Jeremy M. Simon, Gang Greg Wang, Albert S. Baldwin
Published 2023-07-01

Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol

by Karen E. Boschen, Travis S. Ptacek, Matthew E. Berginski, Jeremy M. Simon, Scott E. Parnell
Published 2021-06-01

Widespread Chromatin Accessibility at Repetitive Elements Links Stem Cells with Human Cancer

by Nicholas C. Gomez, Austin J. Hepperla, Raluca Dumitru, Jeremy M. Simon, Fang Fang, Ian J. Davis
Published 2016-11-01

Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration

by Brandon L. Pearson, Jeremy M. Simon, Eric S. McCoy, Gabriela Salazar, Giulia Fragola, Mark J. Zylka
Published 2016-03-01

BET Protein Inhibition Regulates Macrophage Chromatin Accessibility and Microbiota-Dependent Colitis

by Michelle Hoffner O’Connor, Michelle Hoffner O’Connor, Ana Berglind, Ana Berglind, Meaghan M. Kennedy Ng, Meaghan M. Kennedy Ng, Benjamin P. Keith, Benjamin P. Keith, Zachary J. Lynch, Matthew R. Schaner, Erin C. Steinbach, Erin C. Steinbach, Jeremy Herzog, Omar K. Trad, William R. Jeck, Janelle C. Arthur, Janelle C. Arthur, Janelle C. Arthur, Jeremy M. Simon, Jeremy M. Simon, Jeremy M. Simon, Jeremy M. Simon, R. Balfour Sartor, Terrence S. Furey, Terrence S. Furey, Terrence S. Furey, Shehzad Z. Sheikh, Shehzad Z. Sheikh
Published 2022-03-01

Correction to: Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life

by Jessica A. Jiménez, Travis S. Ptacek, Alex H. Tuttle, Ralf S. Schmid, Sheryl S. Moy, Jeremy M. Simon, Mark J. Zylka
Published 2021-05-01

Environmental carcinogens disproportionally mutate genes implicated in neurodevelopmental disorders

by Brennan H. Baker, Shaoyi Zhang, Jeremy M. Simon, Sarah M. McLarnan, Wendy K. Chung, Brandon L. Pearson
Published 2023-08-01

Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life

by Jessica A. Jiménez, Travis S. Ptacek, Alex H. Tuttle, Ralf S. Schmid, Sheryl S. Moy, Jeremy M. Simon, Mark J. Zylka
Published 2020-10-01

Single-cell transcriptomic analysis of mouse neocortical development

by Lipin Loo, Jeremy M. Simon, Lei Xing, Eric S. McCoy, Jesse K. Niehaus, Jiami Guo, E. S. Anton, Mark J. Zylka
Published 2019-01-01

Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.

by Angela M Mabb, Jeremy M Simon, Ian F King, Hyeong-Min Lee, Lin-Kun An, Benjamin D Philpot, Mark J Zylka
Published 2016-01-01

Developmental pyrethroid exposure and age influence phenotypes in a Chd8 haploinsufficient autism mouse model

by Jessica A. Jiménez, Jeremy M. Simon, Wenxin Hu, Sheryl S. Moy, Kathryn M. Harper, Chih-Wei Liu, Kun Lu, Mark J. Zylka
Published 2022-04-01

Rescue of behavioral and electrophysiological phenotypes in a Pitt-Hopkins syndrome mouse model by genetic restoration of Tcf4 expression

by Hyojin Kim, Eric B Gao, Adam Draper, Noah C Berens, Hanna Vihma, Xinyuan Zhang, Alexandra Higashi-Howard, Kimberly D Ritola, Jeremy M Simon, Andrew J Kennedy, Benjamin D Philpot
Published 2022-05-01

Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice

by Lei Xing, Jeremy M. Simon, Travis S. Ptacek, Jason J. Yi, Lipin Loo, Hanqian Mao, Justin M. Wolter, Eric S. McCoy, Smita R. Paranjape, Bonnie Taylor-Blake, Mark J. Zylka
Published 2023-07-01

Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration

by Giulia Fragola, Angela M. Mabb, Bonnie Taylor-Blake, Jesse K. Niehaus, William D. Chronister, Hanqian Mao, Jeremy M. Simon, Hong Yuan, Zibo Li, Michael J. McConnell, Mark J. Zylka
Published 2020-04-01

Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation.

by Gregory R Keele, Bryan C Quach, Jennifer W Israel, Grace A Chappell, Lauren Lewis, Alexias Safi, Jeremy M Simon, Paul Cotney, Gregory E Crawford, William Valdar, Ivan Rusyn, Terrence S Furey
Published 2020-01-01

A small-molecule screen reveals novel modulators of MeCP2 and X-chromosome inactivation maintenance

by Hyeong-Min Lee, M. Bram Kuijer, Nerea Ruiz Blanes, Ellen P. Clark, Megumi Aita, Lorena Galiano Arjona, Agnieszka Kokot, Noah Sciaky, Jeremy M. Simon, Sanchita Bhatnagar, Benjamin D. Philpot, Andrea Cerase
Published 2020-11-01

Depletion of HIV reservoir by activation of ISR signaling in resting CD4+ T cells

by Dajiang Li, Lilly M. Wong, Yuyang Tang, Brigitte Allard, Katherine S. James, George R. Thompson, Satya Dandekar, Edward P. Browne, Qingsheng Li, Jeremy M. Simon, Nancie M. Archin, David M. Margolis, Guochun Jiang
Published 2023-01-01

Early life exposure to vitamin D deficiency impairs molecular mechanisms that regulate liver cholesterol biosynthesis, energy metabolism, inflammation, and detoxification

by Megan M. Knuth, Megan M. Knuth, Jing Xue, Jing Xue, Marwa Elnagheeb, Raad Z. Gharaibeh, Raad Z. Gharaibeh, Sarah A. Schoenrock, Susan McRitchie, Cory Brouwer, Cory Brouwer, Susan J. Sumner, Susan J. Sumner, Lisa Tarantino, Lisa Tarantino, Lisa Tarantino, William Valdar, William Valdar, R. Scott Rector, R. Scott Rector, R. Scott Rector, R. Scott Rector, Jeremy M. Simon, Jeremy M. Simon, Folami Ideraabdullah, Folami Ideraabdullah, Folami Ideraabdullah, Folami Ideraabdullah
Published 2024-05-01

STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity

by Zhichuan Zhu, Xin Zhou, Hongwei Du, Erica W. Cloer, Jiaming Zhang, Liu Mei, Ying Wang, Xianming Tan, Austin J. Hepperla, Jeremy M. Simon, Jeanette Gowen Cook, Michael B. Major, Gianpietro Dotti, Pengda Liu
Published 2023-01-01