New Frontiers in Measuring and Characterizing the HIV Reservoir

by Shane D. Falcinelli, Shane D. Falcinelli, Cristina Ceriani, Cristina Ceriani, David M. Margolis, David M. Margolis, David M. Margolis, Nancie M. Archin, Nancie M. Archin
Published 2019-12-01

Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

by Erin L. Stuelke, Katherine S. James, Jennifer L. Kirchherr, Brigitte Allard, Caroline Baker, Joann D. Kuruc, Joann D. Kuruc, Cindy L. Gay, Cindy L. Gay, David M. Margolis, David M. Margolis, David M. Margolis, David M. Margolis, Nancie M. Archin, Nancie M. Archin
Published 2020-08-01

HIV Latency Reversing Agents have diverse effects on Natural Killer Cell Function

by Carolina Garrido, Carolina Garrido, Adam M Spivak, Natalia Soriano-Sarabia, Natalia Soriano-Sarabia, Mary Ann Checkley, Edward Barker, Jonathan Karn, Vicente Planelles, David M Margolis, David M Margolis, David M Margolis
Published 2016-09-01

Bispecific antibody-derived molecules to target persistent HIV infection

by Jeffrey L. Nordstrom, Guido Ferrari, David M. Margolis
Published 2022-09-01

Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART® Molecules

by Marina Tuyishime, Amir Dashti, Katelyn Faircloth, Shalini Jha, Jeffrey L. Nordstrom, Barton F. Haynes, Barton F. Haynes, Barton F. Haynes, Guido Silvestri, Ann Chahroudi, Ann Chahroudi, Ann Chahroudi, David M. Margolis, David M. Margolis, David M. Margolis, David M. Margolis, Guido Ferrari, Guido Ferrari
Published 2021-08-01

New Concepts in Therapeutic Manipulation of HIV-1 Transcription and Latency: Latency Reversal versus Latency Prevention

by Catherine A. Lewis, David M. Margolis, Edward P. Browne
Published 2023-07-01

Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency

by Todd Bradley, Guido Ferrari, Barton F. Haynes, David M. Margolis, Edward P. Browne
Published 2018-10-01

Highlights from the Seventh International Workshop on HIV Persistence during Therapy, 8–11 December 2015, Miami, Florida, USA

by David M. Margolis, Karl Salzwedel, Nicolas Chomont, Christina Psomas, Jean-Pierre Routy, Guido Poli, Alain Lafeuillade
Published 2016-01-01

3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity

by Huifen Ding, Kalyani Jambunathan, Guochun Jiang, David M. Margolis, Iris Leng, Michael Ihnat, Jian-Xing Ma, Jon Mirsalis, Yuanyuan Zhang
Published 2022-05-01

Interrupting antiretroviral treatment in HIV cure research: scientific and ethical considerations

by Samual A. Garner, Stuart Rennie, Jintanat Ananworanich, Karine Dube, David M. Margolis, Jeremy Sugarman, Randall Tressler, Adam Gilbertson, Liza Dawson
Published 2017-04-01

Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection.

by Nancie M Archin, Manzoor Cheema, Daniel Parker, Ann Wiegand, Ronald J Bosch, John M Coffin, Joseph Eron, Myron Cohen, David M Margolis
Published 2010-02-01

Combinatorial latency reversal activity of inhibitor of apoptosis antagonists with mechanistically distinct classes of HIV latency reversal agents

by Shane D. Falcinelli, David M. Irlbeck, Anne-Marie Turner, Frances Potjewyd, Lindsey I. James, David M. Margolis, Nancie M. Archin, Richard M. Dunham
Published 2019-12-01

Peripheral Vγ9Vδ2 T Cells Are a Novel Reservoir of Latent HIV Infection.

by Natalia Soriano-Sarabia, Nancie M Archin, Rosalie Bateson, Noelle P Dahl, Amanda M Crooks, JoAnn D Kuruc, Carolina Garrido, David M Margolis
Published 2015-10-01

Selective HDAC inhibition for the disruption of latent HIV-1 infection.

by Kirston M Barton, Nancie M Archin, Kara S Keedy, Amy S Espeseth, Yan-ling Zhang, Jennifer Gale, Florence F Wagner, Edward B Holson, David M Margolis
Published 2014-01-01

Microglia-Specific Promoter Activities of HEXB Gene

by Sahil Shah, Sahil Shah, Lilly M. Wong, Kendra Ellis, Kendra Ellis, Brittany Bodnar, Brittany Bodnar, Sami Saribas, Sami Saribas, Julia Ting, Julia Ting, Zhengyu Wei, Zhengyu Wei, Yuyang Tang, Xianwei Wang, Hong Wang, Binhua Ling, David M. Margolis, David M. Margolis, J. Victor Garcia, Wenhui Hu, Wenhui Hu, Guochun Jiang, Guochun Jiang
Published 2022-03-01

Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells

by Julia A. Sung, Katherine Sholtis, Jennifer Kirchherr, Joann D. Kuruc, Cynthia L. Gay, Jeffrey L. Nordstrom, Catherine M. Bollard, Nancie M. Archin, David M. Margolis
Published 2017-09-01

Four Weeks of Treatment With Rifaximin Fails to Significantly Alter Microbial Diversity in Rectal Samples of HIV-Infected Immune Non-Responders (ACTG A5286) Which May be Attributed...

by Brett B. Williams, Stefan J. Green, Ronald J. Bosch, Ellen S. Chan, Jeffrey M. Jacobson, David M. Margolis, Phillip Engen, Alan L. Landay, Cara C. Wilson
Published 2019-09-01

Transient CD4+ T cell depletion during suppressive ART reduces the HIV reservoir in humanized mice

by Lijun Ling, Chandrav De, Rae Ann Spagnuolo, Nurjahan Begum, Shane D. Falcinelli, Nancie M. Archin, Martina Kovarova, Guido Silvestri, Angela Wahl, David M. Margolis, J. Victor Garcia
Published 2023-12-01

Transient CD4+ T cell depletion during suppressive ART reduces the HIV reservoir in humanized mice.

by Lijun Ling, Chandrav De, Rae Ann Spagnuolo, Nurjahan Begum, Shane D Falcinelli, Nancie M Archin, Martina Kovarova, Guido Silvestri, Angela Wahl, David M Margolis, J Victor Garcia
Published 2023-12-01

PP 4.24 – 00176 Impact of cannabis use on immune cell populations and the viral reservoir in HIV-infected people on suppressive antiretroviral therapy

by Shane D. Falcinelli, Alicia Volkheimer, Lesia Semenova, Ethan Wu, Alexander Richardson, Manickam Ashokkumar, David M Margolis, Nancie M. Archin, Cynthia D Rudin, David Murdoch, Edward P Browne
Published 2022-12-01