Correlates of clinical benefit from immunotherapy and targeted therapy in metastatic renal cell carcinoma: comprehensive genomic and transcriptomic analysis

by Paulo Gustavo Bergerot, Nazli Dizman, Yung Lyou, Nicholas Salgia, Daniel Enriquez, Tyler Izatt, Jeffrey M Trent, Sara Byron
Published 2020-07-01

Assessing Combinational Drug Efficacy in Cancer Cells by Using Image-based Dynamic Response Analysis

by Chao Sima, Jianping Hua, Milana Cypert, Tasha Miller, Heather M. Wilson-Robles, Jeffrey M. Trent, Edward R. Dougherty, Michael L. Bittner
Published 2016-03-01

Assessing Combinational Drug Efficacy in Cancer Cells by Using Image-based Dynamic Response Analysis

by Chao Sima, Jianping Hua, Milana Cypert, Tasha Miller, Heather M. Wilson-Robles, Jeffrey M. Trent, Edward R. Dougherty, Michael L. Bittner
Published 2015-01-01

A BAP1 mutation in a Danish family predisposes to uveal melanoma and other cancers.

by Lauren G Aoude, Karin Wadt, Anders Bojesen, Dorthe Crüger, Ake Borg, Jeffrey M Trent, Kevin M Brown, Anne-Marie Gerdes, Göran Jönsson, Nicholas K Hayward
Published 2013-01-01

Molecular Guided Therapy Provides Sustained Clinical Response in Refractory Choroid Plexus Carcinoma

by Albert Cornelius, Jessica Foley, Jeffrey Bond, Abhinav B. Nagulapally, Julie Steinbrecher, William P. D. Hendricks, Maria Rich, Sangeeta Yendrembam, Genevieve Bergendahl, Jeffrey M. Trent, Giselle S. Sholler
Published 2017-09-01

Feasibility of circulating tumor DNA analysis in dogs with naturally occurring malignant and benign splenic lesions

by Patricia Filippsen Favaro, Samuel D. Stewart, Bradon R. McDonald, Jacob Cawley, Tania Contente-Cuomo, Shukmei Wong, William P. D. Hendricks, Jeffrey M. Trent, Chand Khanna, Muhammed Murtaza
Published 2022-04-01

Characterization of X chromosome inactivation using integrated analysis of whole-exome and mRNA sequencing.

by Szabolcs Szelinger, Ivana Malenica, Jason J Corneveaux, Ashley L Siniard, Ahmet A Kurdoglu, Keri M Ramsey, Isabelle Schrauwen, Jeffrey M Trent, Vinodh Narayanan, Matthew J Huentelman, David W Craig
Published 2014-01-01

Assessment of PALB2 as a candidate melanoma susceptibility gene.

by Lauren G Aoude, Mai Xu, Zhen Zhen Zhao, Michael Kovacs, Jane M Palmer, Peter Johansson, Judith Symmons, Jeffrey M Trent, Nicholas G Martin, Grant W Montgomery, Kevin M Brown, Nicholas K Hayward
Published 2014-01-01

Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients.

by Shukmei Wong, E J Ehrhart, Samuel Stewart, Victoria Zismann, Jacob Cawley, Rebecca Halperin, Natalia Briones, Keith Richter, Karthigayini Sivaprakasam, Nieves Perdigones, Tania Contente-Cuomo, Salvatore Facista, Jeffrey M Trent, Muhammed Murtaza, Chand Khanna, William P D Hendricks
Published 2022-01-01

Improved methods for RNAseq-based alternative splicing analysis

by Rebecca F. Halperin, Apurva Hegde, Jessica D. Lang, Elizabeth A. Raupach, C4RCD Research Group, Christophe Legendre, Winnie S. Liang, Patricia M. LoRusso, Aleksandar Sekulic, Jeffrey A. Sosman, Jeffrey M. Trent, Sampathkumar Rangasamy, Patrick Pirrotte, Nicholas J. Schork
Published 2021-05-01

Network Rewiring in Cancer: Applications to Melanoma Cell Lines and the Cancer Genome Atlas Patients

by Kuan-Fu Ding, Kuan-Fu Ding, Darren Finlay, Hongwei Yin, William P. D. Hendricks, Chris Sereduk, Jeffrey Kiefer, Aleksandar Sekulic, Patricia M. LoRusso, Kristiina Vuori, Jeffrey M. Trent, Nicholas J. Schork, Nicholas J. Schork, Nicholas J. Schork, Nicholas J. Schork
Published 2018-07-01

Evaluation of pre-analytical factors affecting plasma DNA analysis

by Havell Markus, Tania Contente-Cuomo, Maria Farooq, Winnie S. Liang, Mitesh J. Borad, Shivan Sivakumar, Simon Gollins, Nhan L. Tran, Harshil D. Dhruv, Michael E. Berens, Alan Bryce, Aleksandar Sekulic, Antoni Ribas, Jeffrey M. Trent, Patricia M. LoRusso, Muhammed Murtaza
Published 2018-05-01

The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer.

by Raffaella Soldi, Tithi Ghosh Halder, Alexis Weston, Trason Thode, Kevin Drenner, Rhonda Lewis, Mohan R Kaadige, Shreyesi Srivastava, Sherin Daniel Ampanattu, Ryan Rodriguez Del Villar, Jessica Lang, Hariprasad Vankayalapati, Bernard Weissman, Jeffrey M Trent, William P D Hendricks, Sunil Sharma
Published 2020-01-01

Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism

by Krystal Ann Orlando, Amber K Douglas, Aierken Abudu, Yemin Wang, Basile Tessier-Cloutier, Weiping Su, Alec Peters, Larry S Sherman, Rayvon Moore, Vinh Nguyen, Gian Luca Negri, Shane Colborne, Gregg B Morin, Friedrich Kommoss, Jessica D Lang, William PD Hendricks, Elizabeth A Raupach, Patrick Pirrotte, David G Huntsman, Jeffrey M Trent, Joel S Parker, Jesse R Raab, Bernard E Weissman
Published 2020-12-01

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis.

by William P D Hendricks, Victoria Zismann, Karthigayini Sivaprakasam, Christophe Legendre, Kelsey Poorman, Waibhav Tembe, Nieves Perdigones, Jeffrey Kiefer, Winnie Liang, Valerie DeLuca, Mitchell Stark, Alison Ruhe, Roe Froman, Nicholas S Duesbery, Nicholas S Duesbery, Megan Washington, Jessica Aldrich, Mark W Neff, Matthew J Huentelman, Nicholas Hayward, Kevin Brown, Douglas Thamm, Gerald Post, Chand Khanna, Barbara Davis, Matthew Breen, Alexander Sekulic, Jeffrey M Trent
Published 2018-09-01

A pilot study of genomic‐guided induction therapy followed by immunotherapy with difluoromethylornithine maintenance for high‐risk neuroblastoma

by Jacqueline M. Kraveka, Elizabeth C. Lewis, Genevieve Bergendahl, William Ferguson, Javier Oesterheld, Elizabeth Kim, Abhinav B. Nagulapally, Karl J. Dykema, Valerie I. Brown, William D. Roberts, Deanna Mitchell, Don Eslin, Derek Hanson, Michael S. Isakoff, Randal K. Wada, Virginia L. Harrod, Jawhar Rawwas, Gina Hanna, William P. D. Hendricks, Sara A. Byron, Matija Snuderl, Jonathan Serrano, Jeffrey M. Trent, Giselle L. Saulnier Sholler
Published 2022-11-01

Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects.

by Xiaobo Yang, Jielin Sun, Yong Gao, Aihua Tan, Haiying Zhang, Yanling Hu, Junjie Feng, Xue Qin, Sha Tao, Zhuo Chen, Seong-Tae Kim, Tao Peng, Ming Liao, Xiaoling Lin, Zengfeng Zhang, Minzhong Tang, Li Li, Linjian Mo, Zhengjia Liang, Deyi Shi, Zhang Huang, Xianghua Huang, Ming Liu, Qian Liu, Shijun Zhang, Jeffrey M Trent, S Lilly Zheng, Jianfeng Xu, Zengnan Mo
Published 2012-09-01

Molecular-guided therapy for the treatment of patients with relapsed and refractory childhood cancers: a Beat Childhood Cancer Research Consortium trial

by Giselle L. Saulnier Sholler, Genevieve Bergendahl, Elizabeth C. Lewis, Jacqueline Kraveka, William Ferguson, Abhinav B. Nagulapally, Karl Dykema, Valerie I. Brown, Michael S. Isakoff, Joseph Junewick, Deanna Mitchell, Jawhar Rawwas, William Roberts, Don Eslin, Javier Oesterheld, Randal K. Wada, Devang Pastakia, Virginia Harrod, Kevin Ginn, Raya Saab, Kevin Bielamowicz, Jason Glover, Eugenia Chang, Gina K. Hanna, Daniel Enriquez, Tyler Izatt, Rebecca F. Halperin, Abigail Moore, Sara A. Byron, William P. D. Hendricks, Jeffrey M. Trent
Published 2024-02-01

Identifying treatment options for BRAFV600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial.

by Patricia M LoRusso, Aleksandar Sekulic, Jeffrey A Sosman, Winnie S Liang, John Carpten, David W Craig, David B Solit, Alan H Bryce, Jeffrey A Kiefer, Jessica Aldrich, Sara Nasser, Rebecca Halperin, Sara A Byron, Mary Jo Pilat, Scott A Boerner, Diane Durecki, William P D Hendricks, Daniel Enriquez, Tyler Izatt, Jonathan Keats, Christophe Legendre, Svetomir N Markovic, Amy Weise, Fatima Naveed, Jessica Schmidt, Gargi D Basu, Shobana Sekar, Jonathan Adkins, Erica Tassone, Karthigayini Sivaprakasam, Victoria Zismann, Valerie S Calvert, Emanuel F Petricoin, Leslie Anne Fecher, Christopher Lao, J Paul Eder, Nicholas J Vogelzang, Jane Perlmutter, Mark Gorman, Barbara Manica, Lisa Fox, Nicholas Schork, Daniel Zelterman, Michelle DeVeaux, Richard W Joseph, C Lance Cowey, Jeffrey M Trent
Published 2021-01-01