Lack of a Functional VHL Gene Product Sensitizes Renal Cell Carcinoma Cells to the Apoptotic Effects of the Protein Synthesis Inhibitor Verrucarin A

by Girma M. Woldemichael, Thomas J. Turbyville, James R. Vasselli, W. Marston Linehan, James B. McMahon
Published 2012-08-01

Synthesis and Biological Evaluation of New Madecassic Acid Derivatives Targeting ERK Cascade Signaling

by Ana S. C. Valdeira, Ana S. C. Valdeira, Daniel A. Ritt, Deborah K. Morrison, James B. McMahon, Kirk R. Gustafson, Jorge A. R. Salvador, Jorge A. R. Salvador
Published 2018-09-01

Tricyclic Guanidine Alkaloids from the Marine Sponge Acanthella cavernosa that Stabilize the Tumor Suppressor PDCD4

by Tanja Grkovic, Johanna S. Blees, Magdalena M. Bayer, Nancy H. Colburn, Cheryl L. Thomas, Curtis J. Henrich, Megan L. Peach, James B. McMahon, Tobias Schmid, Kirk R. Gustafson
Published 2014-08-01

Erioflorin stabilizes the tumor suppressor Pdcd4 by inhibiting its interaction with the E3-ligase β-TrCP1.

by Johanna S Blees, Heidi R Bokesch, Daniela Rübsamen, Kathrin Schulz, Larissa Milke, Magdalena M Bajer, Kirk R Gustafson, Curtis J Henrich, James B McMahon, Nancy H Colburn, Tobias Schmid, Bernhard Brüne
Published 2012-01-01

Antiviral lectins from red and blue-green algae show potent in vitro and in vivo activity against hepatitis C virus.

by Yutaka Takebe, Carrie J Saucedo, Garry Lund, Rie Uenishi, Saiki Hase, Takayo Tsuchiura, Norman Kneteman, Koreen Ramessar, D Lorne J Tyrrell, Masayuki Shirakura, Takaji Wakita, James B McMahon, Barry R O'Keefe
Published 2013-01-01

KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma

by Yong Yean Kim, Berkley E. Gryder, Ranuka Sinniah, Megan L. Peach, Jack F. Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M. Woldemichael, Benjamin Z. Stanton, David Milewski, Joseph J. Barchi, John S. Schneekloth, Raj Chari, Joshua T. Kowalczyk, Shilpa R. Shenoy, Jason R. Evans, Young K. Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O’Neill, Lisa M. Jenkins, Nadya I. Tarasova, Jun S. Wei, James B. McMahon, Barry R. O’Keefe, Robert G. Hawley, Javed Khan
Published 2024-02-01