KekuleScope: prediction of cancer cell line sensitivity and compound potency using convolutional neural networks trained on compound images

by Isidro Cortés-Ciriano, Andreas Bender
Published 2019-06-01

QSAR-derived affinity fingerprints (part 2): modeling performance for potency prediction

by Isidro Cortés-Ciriano, Ctibor Škuta, Andreas Bender, Daniel Svozil
Published 2020-06-01

A molecular portrait of microsatellite instability across multiple cancers

by Isidro Cortes-Ciriano, Sejoon Lee, Woong-Yang Park, Tae-Min Kim, Peter J. Park
Published 2017-06-01

The ALT pathway generates telomere fusions that can be detected in the blood of cancer patients

by Francesc Muyas, Manuel José Gómez Rodriguez, Rita Cascão, Angela Afonso, Carolin M. Sauer, Claudia C. Faria, Isidro Cortés-Ciriano, Ignacio Flores
Published 2024-01-01

Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy

by Yiqun Zhang, Fengju Chen, Erin Pleasance, Laura Williamson, Cameron J. Grisdale, Emma Titmuss, Janessa Laskin, Steven J.M. Jones, Isidro Cortes-Ciriano, Marco A. Marra, Chad J. Creighton
Published 2021-11-01

Profilin 1 deficiency drives mitotic defects and reduces genome stability

by Federica Scotto di Carlo, Sharon Russo, Francesc Muyas, Maria Mangini, Lorenza Garribba, Laura Pazzaglia, Rita Genesio, Flavia Biamonte, Anna Chiara De Luca, Stefano Santaguida, Katia Scotlandi, Isidro Cortés-Ciriano, Fernando Gianfrancesco
Published 2023-01-01

Transcriptional signals of transformation in human cancer

by Gerda Kildisiute, Maria Kalyva, Rasa Elmentaite, Stijn van Dongen, Christine Thevanesan, Alice Piapi, Kirsty Ambridge, Elena Prigmore, Muzlifah Haniffa, Sarah A. Teichmann, Karin Straathof, Isidro Cortés-Ciriano, Sam Behjati, Matthew D. Young
Published 2024-01-01

Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer

by Lina Sieverling, Chen Hong, Sandra D. Koser, Philip Ginsbach, Kortine Kleinheinz, Barbara Hutter, Delia M. Braun, Isidro Cortés-Ciriano, Ruibin Xi, Rolf Kabbe, Peter J. Park, Roland Eils, Matthias Schlesner, PCAWG-Structural Variation Working Group, Benedikt Brors, Karsten Rippe, David T. W. Jones, Lars Feuerbach, PCAWG Consortium
Published 2022-12-01

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.

by Natalie Saini, Steven A Roberts, Leszek J Klimczak, Kin Chan, Sara A Grimm, Shuangshuang Dai, David C Fargo, Jayne C Boyer, William K Kaufmann, Jack A Taylor, Eunjung Lee, Isidro Cortes-Ciriano, Peter J Park, Shepherd H Schurman, Ewa P Malc, Piotr A Mieczkowski, Dmitry A Gordenin
Published 2016-10-01

Genomic footprints of activated telomere maintenance mechanisms in cancer

by Lina Sieverling, Chen Hong, Sandra D. Koser, Philip Ginsbach, Kortine Kleinheinz, Barbara Hutter, Delia M. Braun, Isidro Cortés-Ciriano, Ruibin Xi, Rolf Kabbe, Peter J. Park, Roland Eils, Matthias Schlesner, PCAWG-Structural Variation Working Group, Benedikt Brors, Karsten Rippe, David T. W. Jones, Lars Feuerbach, PCAWG Consortium
Published 2020-02-01

Genomics of MPNST (GeM) Consortium: Rationale and Study Design for Multi-Omic Characterization of NF1-Associated and Sporadic MPNSTs

by David T. Miller, Isidro Cortés-Ciriano, Nischalan Pillay, Angela C. Hirbe, Matija Snuderl, Marilyn M. Bui, Katherine Piculell, Alyaa Al-Ibraheemi, Brendan C. Dickson, Jesse Hart, Kevin Jones, Justin T. Jordan, Raymond H. Kim, Daniel Lindsay, Yoshihiro Nishida, Nicole J. Ullrich, Xia Wang, Peter J. Park, Adrienne M. Flanagan
Published 2020-04-01

21 Increased mutation burden alone is not sufficient to increase immunogenicity of DNA mismatch repair deficient tumors

by Roderick Bronson, Arjun Bhutkar, Peter MK Westcott, Francesc Muyas, Haley Hauck, Olivia C Smith, Nathan Sacks, Zack Ely, Alex M Jaeger, William Rideout, Daniel D Zhang, Mary Clare Beytagh, David Canner, Santiago Naranjo, Abbey Jin, Justin Patten, Amanda M Cruz, Sean-Luc Shanahan, Isidro Cortes-Ciriano, Tyler Jacks
Published 2023-11-01

A user guide for the online exploration and visualization of PCAWG data

by Mary J. Goldman, Junjun Zhang, Nuno A. Fonseca, Isidro Cortés-Ciriano, Qian Xiang, Brian Craft, Elena Piñeiro-Yáñez, Brian D. O’Connor, Wojciech Bazant, Elisabet Barrera, Alfonso Muñoz-Pomer, Robert Petryszak, Anja Füllgrabe, Fatima Al-Shahrour, Maria Keays, David Haussler, John N. Weinstein, Wolfgang Huber, Alfonso Valencia, Peter J. Park, Irene Papatheodorou, Jingchun Zhu, Vincent Ferretti, Miguel Vazquez
Published 2020-07-01

Clonal diversification and histogenesis of malignant germ cell tumours

by Thomas R. W. Oliver, Lia Chappell, Rashesh Sanghvi, Lauren Deighton, Naser Ansari-Pour, Stefan C. Dentro, Matthew D. Young, Tim H. H. Coorens, Hyunchul Jung, Tim Butler, Matthew D. C. Neville, Daniel Leongamornlert, Mathijs A. Sanders, Yvette Hooks, Alex Cagan, Thomas J. Mitchell, Isidro Cortes-Ciriano, Anne Y. Warren, David C. Wedge, Rakesh Heer, Nicholas Coleman, Matthew J. Murray, Peter J. Campbell, Raheleh Rahbari, Sam Behjati
Published 2022-08-01

Experimental validation of in silico target predictions on synergistic protein targets

by Cortes-Ciriano, Isidro, Koutsoukas, Alexios, Abian, Olga, Bender, Andreas, Velazquez-Campoy, Adrian
Published 2013