An in silico analysis identifies drugs potentially modulating the cytokine storm triggered by SARS-CoV-2 infection

by Laura Sanchez-Burgos, Gonzalo Gómez-López, Fátima Al-Shahrour, Oscar Fernandez-Capetillo
Published 2022-01-01

In Silico Drug Prescription for Targeting Cancer Patient Heterogeneity and Prediction of Clinical Outcome

by Elena Piñeiro-Yáñez, María José Jiménez-Santos, Gonzalo Gómez-López, Fátima Al-Shahrour
Published 2019-09-01

Selection upon genome architecture: conservation of functional neighborhoods with changing genes.

by Fátima Al-Shahrour, Pablo Minguez, Tomás Marqués-Bonet, Elodie Gazave, Arcadi Navarro, Joaquín Dopazo
Published 2010-01-01

Nanobodies targeting ABCC3 for immunotargeted applications in glioblastoma

by Eduardo Ruiz-López, Ivana Jovčevska, Ruth González-Gómez, Héctor Tejero, Fátima Al-Shahrour, Serge Muyldermans, Alberto J. Schuhmacher
Published 2022-12-01

Bioinformatics roadmap for therapy selection in cancer genomics

by María José Jiménez‐Santos, Santiago García‐Martín, Coral Fustero‐Torre, Tomás Di Domenico, Gonzalo Gómez‐López, Fátima Al‐Shahrour
Published 2022-11-01

Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation

by Patrick M. Helbling, Elena Piñeiro-Yáñez, Rahel Gerosa, Steffen Boettcher, Fátima Al-Shahrour, Markus G. Manz, César Nombela-Arrieta
Published 2019-12-01

A molecular hypothesis to explain direct and inverse co-morbidities between Alzheimer’s Disease, Glioblastoma and Lung cancer

by Jon Sánchez-Valle, Héctor Tejero, Kristina Ibáñez, José Luis Portero, Martin Krallinger, Fátima Al-Shahrour, Rafael Tabarés-Seisdedos, Anaïs Baudot, Alfonso Valencia
Published 2017-06-01

Analysis of normal-tumour tissue interaction in tumours: prediction of prostate cancer features from the molecular profile of adjacent normal cells.

by Victor Trevino, Mahlet G Tadesse, Marina Vannucci, Fatima Al-Shahrour, Philipp Antczak, Sarah Durant, Andreas Bikfalvi, Joaquin Dopazo, Moray J Campbell, Francesco Falciani
Published 2011-03-01

Beyondcell: targeting cancer therapeutic heterogeneity in single-cell RNA-seq data

by Coral Fustero-Torre, María José Jiménez-Santos, Santiago García-Martín, Carlos Carretero-Puche, Luis García-Jimeno, Vadym Ivanchuk, Tomás Di Domenico, Gonzalo Gómez-López, Fátima Al-Shahrour
Published 2021-12-01

Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships

by Jon Sánchez-Valle, Héctor Tejero, José María Fernández, David Juan, Beatriz Urda-García, Salvador Capella-Gutiérrez, Fátima Al-Shahrour, Rafael Tabarés-Seisdedos, Anaïs Baudot, Vera Pancaldi, Alfonso Valencia
Published 2020-06-01

The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data

by Pablo Fernández-Navarro, Pilar López-Nieva, Elena Piñeiro-Yañez, Gonzalo Carreño-Tarragona, Joaquín Martinez-López, Raúl Sánchez Pérez, Ángel Aroca, Fátima Al-Shahrour, María Ángeles Cobos-Fernández, José Fernández-Piqueras
Published 2019-10-01

Activation of the integrated stress response is a vulnerability for multidrug‐resistant FBXW7‐deficient cells

by Laura Sanchez‐Burgos, Belén Navarro‐González, Santiago García‐Martín, Oleksandra Sirozh, Jorge Mota‐Pino, Elena Fueyo‐Marcos, Héctor Tejero, Marta Elena Antón, Matilde Murga, Fátima Al‐Shahrour, Oscar Fernandez‐Capetillo
Published 2022-09-01

Peripheral Blood Mononuclear Cells Predict Therapeutic Efficacy of Immunotherapy in NSCLC

by Jacobo Rogado, Fernando Pozo, Kevin Troule, José Miguel Sánchez-Torres, Nuria Romero-Laorden, Rebeca Mondejar, Olga Donnay, Anabel Ballesteros, Vilma Pacheco-Barcia, Javier Aspa, Fátima Al-Shahrour, Arantzazu Alfranca, Ramon Colomer
Published 2022-06-01

Inactivation of EMILIN-1 by Proteolysis and Secretion in Small Extracellular Vesicles Favors Melanoma Progression and Metastasis

by Ana Amor López, Marina S. Mazariegos, Alessandra Capuano, Pilar Ximénez-Embún, Marta Hergueta-Redondo, Juan Ángel Recio, Eva Muñoz, Fátima Al-Shahrour, Javier Muñoz, Diego Megías, Roberto Doliana, Paola Spessotto, Héctor Peinado
Published 2021-07-01

PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data

by Elena Piñeiro-Yáñez, Miguel Reboiro-Jato, Gonzalo Gómez-López, Javier Perales-Patón, Kevin Troulé, José Manuel Rodríguez, Héctor Tejero, Takeshi Shimamura, Pedro Pablo López-Casas, Julián Carretero, Alfonso Valencia, Manuel Hidalgo, Daniel Glez-Peña, Fátima Al-Shahrour
Published 2018-05-01

A comprehensive database for integrated analysis of omics data in autoimmune diseases

by Jordi Martorell-Marugán, Raúl López-Domínguez, Adrián García-Moreno, Daniel Toro-Domínguez, Juan Antonio Villatoro-García, Guillermo Barturen, Adoración Martín-Gómez, Kevin Troule, Gonzalo Gómez-López, Fátima Al-Shahrour, Víctor González-Rumayor, María Peña-Chilet, Joaquín Dopazo, Julio Sáez-Rodríguez, Marta E. Alarcón-Riquelme, Pedro Carmona-Sáez
Published 2021-06-01

Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas

by Marina Salmón, Ruth Álvarez-Díaz, Coral Fustero-Torre, Oksana Brehey, Carmen G. Lechuga, Manuel Sanclemente, Fernando Fernández-García, Alejandra López-García, María Carmen Martín-Guijarro, Sandra Rodríguez-Perales, Emily Bousquet-Mur, Lucía Morales-Cacho, Francisca Mulero, Fátima Al-Shahrour, Lola Martínez, Orlando Domínguez, Eduardo Caleiras, Sagrario Ortega, Carmen Guerra, Monica Musteanu, Matthias Drosten, Mariano Barbacid
Published 2023-04-01

Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity

by Marta Barradas, Adrián Plaza, Gonzalo Colmenarejo, Iolanda Lázaro, Luis Filipe Costa-Machado, Roberto Martín-Hernández, Victor Micó, José Luis López-Aceituno, Jesús Herranz, Cristina Pantoja, Hector Tejero, Alberto Diaz-Ruiz, Fatima Al-Shahrour, Lidia Daimiel, Viviana Loria-Kohen, Ana Ramirez de Molina, Alejo Efeyan, Manuel Serrano, Oscar J. Pozo, Aleix Sala-Vila, Pablo J. Fernandez-Marcos
Published 2022-09-01

A user guide for the online exploration and visualization of PCAWG data

by Mary J. Goldman, Junjun Zhang, Nuno A. Fonseca, Isidro Cortés-Ciriano, Qian Xiang, Brian Craft, Elena Piñeiro-Yáñez, Brian D. O’Connor, Wojciech Bazant, Elisabet Barrera, Alfonso Muñoz-Pomer, Robert Petryszak, Anja Füllgrabe, Fatima Al-Shahrour, Maria Keays, David Haussler, John N. Weinstein, Wolfgang Huber, Alfonso Valencia, Peter J. Park, Irene Papatheodorou, Jingchun Zhu, Vincent Ferretti, Miguel Vazquez
Published 2020-07-01

Immunophenotype and Transcriptome Profile of Patients With Multiple Sclerosis Treated With Fingolimod: Setting Up a Model for Prediction of Response in a 2-Year Translational Study

by Irene Moreno-Torres, Irene Moreno-Torres, Coral González-García, Marco Marconi, Aranzazu García-Grande, Luis Rodríguez-Esparragoza, Víctor Elvira, Elvira Ramil, Lucía Campos-Ruíz, Ruth García-Hernández, Ruth García-Hernández, Fátima Al-Shahrour, Coral Fustero-Torre, Alicia Sánchez-Sanz, Antonio García-Merino, Antonio García-Merino, Antonio García-Merino, Antonio García-Merino, Antonio José Sánchez López, Antonio José Sánchez López, Antonio José Sánchez López
Published 2018-07-01