Role of in silico structural modeling in predicting immunogenic neoepitopes for cancer vaccine development

by Neeha Zaidi, Mariya Soban, Fangluo Chen, Heather Kinkead, Jocelyn Mathew, Mark Yarchoan, Todd D. Armstrong, Shozeb Haider, Elizabeth M. Jaffee
Published 2020-09-01

856 INBRX-106: a novel hexavalent anti-OX40 agonist for the treatment of solid tumors

by Quinn Deveraux, Heather Kinkead, Kyle Jones, Bryan Becklund, Florian Sulzmaier, John Timmer, Brendan Eckelman, Analeah Heidt, William Crago, Emily Rowell, Elisabeth Torretti
Published 2021-11-01

12 Key pharmacokinetic and pharmacodynamic parameters that correlate with the anti-tumor activity of a bispecific PD-L1 conditional 4–1BB agonist

by Quinn Deveraux, Heather Kinkead, Chelsie Macedo, Angelica Sanabria, Garrett Cyprus, Rajay Pandit, James Kalabus, Bryan Becklund, Florian Sulzmaier, John Timmer, Brendan Eckelman, Analeah Heidt
Published 2021-11-01

Functional stability of unliganded envelope glycoprotein spikes among isolates of human immunodeficiency virus type 1 (HIV-1).

by Nitish Agrawal, Daniel P Leaman, Eric Rowcliffe, Heather Kinkead, Raman Nohria, Junya Akagi, Katherine Bauer, Sean X Du, Robert G Whalen, Dennis R Burton, Michael B Zwick
Published 2011-01-01

722 INBRX-121 is an NKp46-targeted detuned IL-2 with antitumor activity as a monotherapy or in combination with multiple cancer immunotherapy modalities

by Heather Kinkead, Chelsie Macedo, Angelica Sanabria, Rajay Pandit, Florian Sulzmaier, John Timmer, Brendan Eckelman, Analeah Heidt, Anya Polovina, Nadja Kern, Abrahim Hussain, Sae Jeong Ahn, William Crago
Published 2021-11-01

742 Phase 1/2 study of the bispecific 4–1BB and PD-L1 antibody INBRX-105 alone and in combination with pembrolizumab in select solid tumors

by David Hong, Manish Sharma, Erminia Massarelli, Heather Kinkead, Naomi B Haas, Rachel E Sanborn, Ralph J Hauke, Anthony W Tolcher, Neal Akhave, Jong Chul Park, Jennifer Carlisle, John Hamm, Alexander I Spira, David Berz, Vasily Andrianov, Brianne O’Neill, Justin A Call, Frank Yung-Chin Tsai, D Ross Camidge
Published 2023-11-01