High cyclin E staining index in blastemal, stromal or epithelial cells is correlated with tumor aggressiveness in patients with nephroblastoma.

by Dominique Berrebi, Julie Leclerc, Gudrun Schleiermacher, Isabelle Zaccaria, Liliane Boccon-Gibod, Monique Fabre, Francis Jaubert, Alaa El Ghoneimi, Cécile Jeanpierre, Michel Peuchmaur
Published 2008-01-01

Seasonality of main childhood embryonal tumours and rhabdomyosarcoma, France, 2000–2015

by Danielle Awounou, Brigitte Lacour, Emmanuel Desandes, Sandra Guissou, Nathalie Cassoux, François Doz, Christelle Dufour, Véronique Minard‐Colin, Gudrun Schleiermacher, Sophie Taque, Arnauld Verschuur, Jacqueline Clavel, Stéphanie Goujon
Published 2023-04-01

Radiogenomics of neuroblastomas: Relationships between imaging phenotypes, tumor genomic profile and survival.

by Hervé J Brisse, Thomas Blanc, Gudrun Schleiermacher, Véronique Mosseri, Pascale Philippe-Chomette, Isabelle Janoueix-Lerosey, Gaelle Pierron, Eve Lapouble, Michel Peuchmaur, Paul Fréneaux, Louise Galmiche, Nathalie Algret, Matthieu Peycelon, Jean Michon, Olivier Delattre, Sabine Sarnacki
Published 2017-01-01

Suprarenal Masses in Very Young Infants: Is It Safe to Watch and Wait? Report of a SIOPEN Observational Study Results

by Vassilios Papadakis, Vanessa Segura, Massimo Conte, Dominique Plantaz, Andrea Di Cataldo, Gudrun Schleiermacher, Kate Wheeler, Jose D. Bermúdez, Shifra Ash, Bénédicte Brichard, Ruth Ladenstein, Valérie Combaret, Sabine Sarnacki, Anna Maria Fagnani, Claudio Granata, Adela Cañete
Published 2022-08-01

Sequential genomic analysis using a multisample/multiplatform approach to better define rhabdomyosarcoma progression and relapse

by Henry de Traux de Wardin, Josephine K. Dermawan, Marie-Sophie Merlin, Leonard H. Wexler, Daniel Orbach, Fabio Vanoli, Gudrun Schleiermacher, Birgit Geoerger, Stelly Ballet, Delphine Guillemot, Eléonore Frouin, Stacy Cyrille, Olivier Delattre, Gaelle Pierron, Cristina R. Antonescu
Published 2023-09-01

Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.

by Valentina Boeva, Stéphanie Jouannet, Romain Daveau, Valérie Combaret, Cécile Pierre-Eugène, Alex Cazes, Caroline Louis-Brennetot, Gudrun Schleiermacher, Sandrine Ferrand, Gaëlle Pierron, Alban Lermine, Thomas Rio Frio, Virginie Raynal, Gilles Vassal, Emmanuel Barillot, Olivier Delattre, Isabelle Janoueix-Lerosey
Published 2013-01-01

Minimally invasive classification of paediatric solid tumours using reduced representation bisulphite sequencing of cell-free DNA: a proof-of-principle study

by Ruben Van Paemel, Andries De Koker, Charlotte Vandeputte, Lieke van Zogchel, Tim Lammens, Geneviève Laureys, Jo Vandesompele, Gudrun Schleiermacher, Mathieu Chicard, Nadine Van Roy, Ales Vicha, G.A.M. Tytgat, Nico Callewaert, Katleen De Preter, Bram De Wilde
Published 2021-02-01

Clinical characteristics and outcome of patients with neuroblastoma presenting genomic amplification of loci other than MYCN.

by Anne Guimier, Sandrine Ferrand, Gaëlle Pierron, Jérôme Couturier, Isabelle Janoueix-Lerosey, Valérie Combaret, Véronique Mosseri, Estelle Thebaud, Marion Gambart, Dominique Plantaz, Aurélien Marabelle, Carole Coze, Xavier Rialland, Sylvie Fasola, Eve Lapouble, Paul Fréneaux, Michel Peuchmaur, Jean Michon, Olivier Delattre, Gudrun Schleiermacher
Published 2014-01-01

Cell-Free DNA Extracted from CSF for the Molecular Diagnosis of Pediatric Embryonal Brain Tumors

by Mathieu Chicard, Yasmine Iddir, Julien Masliah Planchon, Valérie Combaret, Valéry Attignon, Alexandra Saint-Charles, Didier Frappaz, Cécile Faure-Conter, Kévin Beccaria, Pascale Varlet, Birgit Geoerger, Sylvain Baulande, Gaelle Pierron, Yassine Bouchoucha, François Doz, Olivier Delattre, Joshua J. Waterfall, Franck Bourdeaut, Gudrun Schleiermacher
Published 2023-07-01

Exosomal microRNAs from Longitudinal Liquid Biopsies for the Prediction of Response to Induction Chemotherapy in High-Risk Neuroblastoma Patients: A Proof of Concept SIOPEN Study <...

by Martina Morini, Davide Cangelosi, Daniela Segalerba, Danilo Marimpietri, Federica Raggi, Aurora Castellano, Doriana Fruci, Jaime Font de Mora, Adela Cañete, Yania Yáñez, Virginie Viprey, Maria Valeria Corrias, Barbara Carlini, Annalisa Pezzolo, Gudrun Schleiermacher, Katia Mazzocco, Ruth Ladenstein, Angela Rita Sementa, Massimo Conte, Alberto Garaventa, Susan Burchill, Roberto Luksch, Maria Carla Bosco, Alessandra Eva, Luigi Varesio
Published 2019-09-01

Intra‐ and extra‐cranial BCOR‐ITD tumours are separate entities within the BCOR‐rearranged family

by Yassine Bouchoucha, Arnault Tauziède‐Espariat, Arnaud Gauthier, Delphine Guillemot, Dorian Bochaton, Julien Vibert, Matthieu Carton, Sarah Watson, Sandrine Grossetête, Chloé Quignot, Daniel Orbach, Nadège Corradini, Gudrun Schleiermacher, Franck Bourdeaut, Marie Simbozel, Christelle Dufour, Véronique Minard‐Colin, Mehdi Brahmi, Franck Tirode, Daniel Pissaloux, Marie Karanian, Marie‐Christine Machet, Julien Masliah‐Planchon, Olivier Delattre, Liesbeth Cardoen, Gaëlle Pierron, François Doz
Published 2022-05-01

Single-cell transcriptomics reveals shared immunosuppressive landscapes of mouse and human neuroblastoma

by Birgit Geoerger, Aurélien Marabelle, Gaelle Pierron, Nadege Gruel, Arnaud Gauthier, Olivier Delattre, Gudrun Schleiermacher, Ana Costa, Cécile Thirant, Amira Kramdi, Cécile Pierre-Eugène, Caroline Louis-Brennetot, Orphée Blanchard, Didier Surdez, Eve Lapouble, Deborah Sitbon, Hervé Brisse, Paul Fréneaux, Mylène Bohec, Virginie Raynal, Sylvain Baulande, Renaud Leclere, Gabriel Champenois, Andre Nicolas, Didier Meseure, Angela Bellini, Fatima Mechta-Grigoriou, Laurie Menger, Isabelle Janoueix-Lerosey
Published 2022-08-01

Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma

by Cécile Thirant, Agathe Peltier, Simon Durand, Amira Kramdi, Caroline Louis-Brennetot, Cécile Pierre-Eugène, Margot Gautier, Ana Costa, Amandine Grelier, Sakina Zaïdi, Nadège Gruel, Irène Jimenez, Eve Lapouble, Gaëlle Pierron, Déborah Sitbon, Hervé J. Brisse, Arnaud Gauthier, Paul Fréneaux, Sandrine Grossetête, Laura G. Baudrin, Virginie Raynal, Sylvain Baulande, Angela Bellini, Jaydutt Bhalshankar, Angel M. Carcaboso, Birgit Geoerger, Hermann Rohrer, Didier Surdez, Valentina Boeva, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey
Published 2023-05-01

Divergent HLA variations and heterogeneous expression but recurrent HLA loss-of- heterozygosity and common HLA-B and TAP transcriptional silencing across advanced pediatric solid c...

by Wan Ching Lim, Wan Ching Lim, Wan Ching Lim, Maria Eugenia Marques Da Costa, Karine Godefroy, Eric Jacquet, Loren Gragert, Windy Rondof, Windy Rondof, Antonin Marchais, Antonin Marchais, Naima Nhiri, Davide Dalfovo, Mathias Viard, Mathias Viard, Nizar Labaied, Asif M. Khan, Philippe Dessen, Alessandro Romanel, Claudia Pasqualini, Claudia Pasqualini, Gudrun Schleiermacher, Mary Carrington, Mary Carrington, Mary Carrington, Laurence Zitvogel, Jean-Yves Scoazec, Birgit Geoerger, Birgit Geoerger, Jerome Salmon
Published 2024-01-01

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

by Bieke Decaesteker, Geertrui Denecker, Christophe Van Neste, Emmy M. Dolman, Wouter Van Loocke, Moritz Gartlgruber, Carolina Nunes, Fanny De Vloed, Pauline Depuydt, Karen Verboom, Dries Rombaut, Siebe Loontiens, Jolien De Wyn, Waleed M. Kholosy, Bianca Koopmans, Anke H. W. Essing, Carl Herrmann, Daniel Dreidax, Kaat Durinck, Dieter Deforce, Filip Van Nieuwerburgh, Anton Henssen, Rogier Versteeg, Valentina Boeva, Gudrun Schleiermacher, Johan van Nes, Pieter Mestdagh, Suzanne Vanhauwaert, Johannes H. Schulte, Frank Westermann, Jan J. Molenaar, Katleen De Preter, Frank Speleman
Published 2018-11-01

A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors

by Maria Eugénia Marques Da Costa, Sakina Zaidi, Jean-Yves Scoazec, Robin Droit, Wan Ching Lim, Antonin Marchais, Jerome Salmon, Sarah Cherkaoui, Raphael J. Morscher, Anouchka Laurent, Sébastien Malinge, Thomas Mercher, Séverine Tabone-Eglinger, Isabelle Goddard, Francoise Pflumio, Julien Calvo, Francoise Redini, Natacha Entz-Werlé, Aroa Soriano, Alberto Villanueva, Stefano Cairo, Pascal Chastagner, Massimo Moro, Cormac Owens, Michela Casanova, Raquel Hladun-Alvaro, Pablo Berlanga, Estelle Daudigeos-Dubus, Philippe Dessen, Laurence Zitvogel, Ludovic Lacroix, Gaelle Pierron, Olivier Delattre, Gudrun Schleiermacher, Didier Surdez, Birgit Geoerger
Published 2023-09-01

Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden

by Peter Peneder, Adrian M. Stütz, Didier Surdez, Manuela Krumbholz, Sabine Semper, Mathieu Chicard, Nathan C. Sheffield, Gaelle Pierron, Eve Lapouble, Marcus Tötzl, Bekir Ergüner, Daniele Barreca, André F. Rendeiro, Abbas Agaimy, Heidrun Boztug, Gernot Engstler, Michael Dworzak, Marie Bernkopf, Sabine Taschner-Mandl, Inge M. Ambros, Ola Myklebost, Perrine Marec-Bérard, Susan Ann Burchill, Bernadette Brennan, Sandra J. Strauss, Jeremy Whelan, Gudrun Schleiermacher, Christiane Schaefer, Uta Dirksen, Caroline Hutter, Kjetil Boye, Peter F. Ambros, Olivier Delattre, Markus Metzler, Christoph Bock, Eleni M. Tomazou
Published 2021-05-01

A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma

by Laura D. Gamble, Stefania Purgato, Michelle J. Henderson, Simone Di Giacomo, Amanda J. Russell, Paolo Pigini, Jayne Murray, Emanuele Valli, Giorgio Milazzo, Federico M. Giorgi, Mark Cowley, Lesley J. Ashton, Jaydutt Bhalshankar, Gudrun Schleiermacher, Ali Rihani, Tom Van Maerken, Jo Vandesompele, Frank Speleman, Rogier Versteeg, Jan Koster, Angelika Eggert, Rosa Noguera, Raymond L. Stallings, Gian Paolo Tonini, Kwun Fong, Zalman Vaksman, Sharon J. Diskin, John M. Maris, Wendy B. London, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Giovanni Perini, Murray D. Norris, Michelle Haber
Published 2021-04-01