Development of an epitope-based HIV-1 vaccine strategy from HIV-1 lipopeptide to dendritic-based vaccines

by Mathieu Surenaud, Christine Lacabaratz, Gérard Zurawski, Yves Lévy, Jean-Daniel Lelièvre
Published 2017-10-01

Anti-CD40 Antibody Fused to CD40 Ligand Is a Superagonist Platform for Adjuvant Intrinsic DC-Targeting Vaccines

by Valentina Ceglia, Valentina Ceglia, Valentina Ceglia, Sandra Zurawski, Sandra Zurawski, Monica Montes, Monica Montes, Mitchell Kroll, Mitchell Kroll, Aurélie Bouteau, Aurélie Bouteau, Zhiqing Wang, Zhiqing Wang, Jerome Ellis, Jerome Ellis, Botond Z. Igyártó, Botond Z. Igyártó, Yves Lévy, Yves Lévy, Gerard Zurawski, Gerard Zurawski
Published 2022-01-01

Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo.

by Anne-Laure Flamar, Vanessa Contreras, Sandra Zurawski, Monica Montes, Nathatlie Dereuddre-Bosquet, Frédéric Martinon, Jacques Banchereau, Roger Le Grand, Gerard Zurawski, Yves Levy
Published 2015-01-01

DC Subsets Regulate Humoral Immune Responses by Supporting the Differentiation of Distinct Tfh Cells

by Aurélie Bouteau, Aurélie Bouteau, Jérôme Kervevan, Jérôme Kervevan, Jérôme Kervevan, Qingtai Su, Sandra M. Zurawski, Sandra M. Zurawski, Vanessa Contreras, Vanessa Contreras, Nathalie Dereuddre-Bosquet, Nathalie Dereuddre-Bosquet, Roger Le Grand, Roger Le Grand, Gerard Zurawski, Gerard Zurawski, Sylvain Cardinaud, Sylvain Cardinaud, Sylvain Cardinaud, Yves Levy, Yves Levy, Yves Levy, Botond Z. Igyártó
Published 2019-05-01

A Framework to Identify Antigen-Expanded T Cell Receptor Clusters Within Complex Repertoires

by Valentina Ceglia, Valentina Ceglia, Valentina Ceglia, Erin J. Kelley, Annalee S. Boyle, Sandra Zurawski, Sandra Zurawski, Heather L. Mead, Caroline E. Harms, Jean-Philippe Blanck, Anne-Laure Flamar, Anne-Laure Flamar, Anne-Laure Flamar, Jung Hwa Kirschman, Paul Ogongo, Joel D. Ernst, Yves Levy, Yves Levy, Gerard Zurawski, Gerard Zurawski, John A. Altin
Published 2021-11-01

HIV-1 T cell epitopes targeted to Rhesus macaque CD40 and DCIR: A comparative study of prototype dendritic cell targeting therapeutic vaccine candidates.

by Anne-Laure Flamar, Henri Bonnabau, Sandra Zurawski, Christine Lacabaratz, Monica Montes, Laura Richert, Aurelie Wiedemann, Lindsey Galmin, Deborah Weiss, Anthony Cristillo, Lauren Hudacik, Andres Salazar, Cécile Peltekian, Rodolphe Thiebaut, Gerard Zurawski, Yves Levy
Published 2018-01-01

Functional Specialty of CD40 and Dendritic Cell Surface Lectins for Exogenous Antigen Presentation to CD8+ and CD4+ T Cells

by Wenjie Yin, Laurent Gorvel, Sandra Zurawski, Dapeng Li, Ling Ni, Dorothée Duluc, Katherine Upchurch, JongRok Kim, Chao Gu, Richard Ouedraogo, Zhiqing Wang, Yaming Xue, HyeMee Joo, Jean-Pierre Gorvel, Gerard Zurawski, SangKon Oh
Published 2016-03-01

TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice.

by Véronique Godot, Colas Tcherakian, Laurine Gil, Iñaki Cervera-Marzal, Guangming Li, Liang Cheng, Nicolas Ortonne, Jean-Daniel Lelièvre, Giuseppe Pantaleo, Craig Fenwick, Mireille Centlivre, Hugo Mouquet, Sylvain Cardinaud, Sandra M Zurawski, Gerard Zurawski, Pierre Milpied, Lishan Su, Yves Lévy
Published 2020-11-01

Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells.

by Anna Martirosyan, Camino Pérez-Gutierrez, Romain Banchereau, Hélène Dutartre, Patrick Lecine, Melissa Dullaers, Marielle Mello, Suzana Pinto Salcedo, Alexandre Muller, Lee Leserman, Yves Levy, Gerard Zurawski, Sandy Zurawski, Edgardo Moreno, Ignacio Moriyón, Eynav Klechevsky, Jacques Banchereau, Sangkon Oh, Jean-Pierre Gorvel
Published 2012-01-01

TLR9- and CD40-Targeting Vaccination Promotes Human B Cell Maturation and IgG Induction via pDC-Dependent Mechanisms in Humanized Mice

by Liang Cheng, Liang Cheng, Guangming Li, Guangming Li, Caroline Marnata Pellegry, Fumihiko Yasui, Fumihiko Yasui, Feng Li, Feng Li, Sandra M. Zurawski, Gerard Zurawski, Yves Levy, Yves Levy, Jenny P.-Y. Ting, Jenny P.-Y. Ting, Jenny P.-Y. Ting, Lishan Su, Lishan Su
Published 2021-05-01

Intradermal vaccination prevents anti-MOG autoimmune encephalomyelitis in macaquesResearch in context

by Claire-Maëlle Fovet, Lev Stimmer, Vanessa Contreras, Philippe Horellou, Audrey Hubert, Nabila Seddiki, Catherine Chapon, Sabine Tricot, Carole Leroy, Julien Flament, Julie Massonneau, Nicolas Tchitchek, Bert A. 't Hart, Sandra Zurawski, Peter Klucar, Philippe Hantraye, Kumaran Deiva, Gerard Zurawski, SangKon Oh, Roger Le Grand, Ché Serguera
Published 2019-09-01

Modelling the response to vaccine in non-human primates to define SARS-CoV-2 mechanistic correlates of protection

by Marie Alexandre, Romain Marlin, Mélanie Prague, Severin Coleon, Nidhal Kahlaoui, Sylvain Cardinaud, Thibaut Naninck, Benoit Delache, Mathieu Surenaud, Mathilde Galhaut, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Pauline Maisonnasse, Mireille Centlivre, Christine Lacabaratz, Aurelie Wiedemann, Sandra Zurawski, Gerard Zurawski, Olivier Schwartz, Rogier W Sanders, Roger Le Grand, Yves Levy, Rodolphe Thiébaut
Published 2022-07-01

Targeting human langerin promotes HIV-1 specific humoral immune responses.

by Jérôme Kervevan, Aurélie Bouteau, Juliane S Lanza, Adele Hammoudi, Sandra Zurawski, Mathieu Surenaud, Lydie Dieudonné, Marion Bonnet, Cécile Lefebvre, Hakim Hocini, Romain Marlin, Aurélie Guguin, Barbara Hersant, Oana Hermeziu, Elisabeth Menu, Christine Lacabaratz, Jean-Daniel Lelièvre, Gerard Zurawski, Véronique Godot, Sandrine Henri, Botond Z Igyártó, Yves Levy, Sylvain Cardinaud
Published 2021-07-01

Design, immunogenicity, and efficacy of a pan-sarbecovirus dendritic-cell targeting vaccine

by Séverin Coléon, Aurélie Wiedemann, Mathieu Surénaud, Christine Lacabaratz, Sophie Hue, Mélanie Prague, Minerva Cervantes-Gonzalez, Zhiqing Wang, Jerome Ellis, Amandine Sansoni, Camille Pierini, Quentin Bardin, Manon Fabregue, Sarah Sharkaoui, Philippe Hoest, Léa Dupaty, Florence Picard, Marwa El Hajj, Mireille Centlivre, Jade Ghosn, Rodolphe Thiébaut, Sylvain Cardinaud, Bernard Malissen, Gérard Zurawski, Ana Zarubica, Sandra M. Zurawski, Véronique Godot, Yves Lévy
Published 2022-06-01

Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques.

by Gerard Zurawski, Sandra Zurawski, Anne-Laure Flamar, Laura Richert, Ralf Wagner, Georgia D Tomaras, David C Montefiori, Mario Roederer, Guido Ferrari, Christine Lacabaratz, Henri Bonnabau, Peter Klucar, Zhiqing Wang, Kathryn E Foulds, Shing-Fen Kao, Nicole L Yates, Celia LaBranche, Bertram L Jacobs, Karen Kibler, Benedikt Asbach, Alexander Kliche, Andres Salazar, Steve Reed, Steve Self, Raphael Gottardo, Lindsey Galmin, Deborah Weiss, Anthony Cristillo, Rodolphe Thiebaut, Giuseppe Pantaleo, Yves Levy
Published 2016-01-01

Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models

by Kevin O. Saunders, Laurent K. Verkoczy, Chuancang Jiang, Jinsong Zhang, Robert Parks, Haiyan Chen, Max Housman, Hilary Bouton-Verville, Xiaoying Shen, Ashley M. Trama, Richard Scearce, Laura Sutherland, Sampa Santra, Amanda Newman, Amanda Eaton, Kai Xu, Ivelin S. Georgiev, M. Gordon Joyce, Georgia D. Tomaras, Mattia Bonsignori, Steven G. Reed, Andres Salazar, John R. Mascola, M. Anthony Moody, Derek W. Cain, Mireille Centlivre, Sandra Zurawski, Gerard Zurawski, Harold P. Erickson, Peter D. Kwong, S. Munir Alam, Yves Levy, David C. Montefiori, Barton F. Haynes
Published 2017-12-01

Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques

by Romain Marlin, Veronique Godot, Sylvain Cardinaud, Mathilde Galhaut, Severin Coleon, Sandra Zurawski, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Pauline Maisonnasse, Léa Dupaty, Craig Fenwick, Thibaut Naninck, Julien Lemaitre, Mario Gomez-Pacheco, Nidhal Kahlaoui, Vanessa Contreras, Francis Relouzat, Raphaël Ho Tsong Fang, Zhiqing Wang, Jerome Ellis, Catherine Chapon, Mireille Centlivre, Aurelie Wiedemann, Christine Lacabaratz, Mathieu Surenaud, Inga Szurgot, Peter Liljeström, Delphine Planas, Timothée Bruel, Olivier Schwartz, Sylvie van der Werf, Giuseppe Pantaleo, Mélanie Prague, Rodolphe Thiébaut, Gerard Zurawski, Yves Lévy, Roger Le Grand
Published 2021-09-01