Vaccine-associated enhanced disease in humans and animal models: Lessons and challenges for vaccine development

by Julie Bigay, Roger Le Grand, Frédéric Martinon, Pauline Maisonnasse
Published 2022-08-01

Molecular and Cellular Dynamics in the Skin, the Lymph Nodes, and the Blood of the Immune Response to Intradermal Injection of Modified Vaccinia Ankara Vaccine

by Pierre Rosenbaum, Pierre Rosenbaum, Nicolas Tchitchek, Candie Joly, Lev Stimmer, Lev Stimmer, Hakim Hocini, Hakim Hocini, Nathalie Dereuddre-Bosquet, Anne-Sophie Beignon, Anne-Sophie Beignon, Catherine Chapon, Catherine Chapon, Yves Levy, Yves Levy, Roger Le Grand, Roger Le Grand, Frédéric Martinon, Frédéric Martinon
Published 2018-04-01

Optimize Prime/Boost Vaccine Strategies: Trained Immunity as a New Player in the Game

by Jean-Louis Palgen, Jean-Louis Palgen, Yanis Feraoun, Gaëlle Dzangué-Tchoupou, Candie Joly, Frédéric Martinon, Roger Le Grand, Anne-Sophie Beignon
Published 2021-03-01

Electroporation as a vaccine delivery system and a natural adjuvant to intradermal administration of plasmid DNA in macaques

by Biliana Todorova, Lucille Adam, Slobodan Culina, Raphaël Boisgard, Frédéric Martinon, Antonio Cosma, Mart Ustav, Thierry Kortulewski, Roger Le Grand, Catherine Chapon
Published 2017-06-01

Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo.

by Anne-Laure Flamar, Vanessa Contreras, Sandra Zurawski, Monica Montes, Nathatlie Dereuddre-Bosquet, Frédéric Martinon, Jacques Banchereau, Roger Le Grand, Gerard Zurawski, Yves Levy
Published 2015-01-01

Paradoxical Effect of Chloroquine Treatment in Enhancing Chikungunya Virus Infection

by Pierre Roques, Simon-Djamel Thiberville, Laurence Dupuis-Maguiraga, Fok-Moon Lum, Karine Labadie, Frédéric Martinon, Gabriel Gras, Pierre Lebon, Lisa F. P. Ng, Xavier de Lamballerie, Roger Le Grand
Published 2018-05-01

The Route of Vaccine Administration Determines Whether Blood Neutrophils Undergo Long-Term Phenotypic Modifications

by Yanis Feraoun, Jean-Louis Palgen, Candie Joly, Nicolas Tchitchek, Ernesto Marcos-Lopez, Nathalie Dereuddre-Bosquet, Anne-Sophie Gallouet, Vanessa Contreras, Yves Lévy, Yves Lévy, Frédéric Martinon, Roger Le Grand, Anne-Sophie Beignon
Published 2022-01-01

Vaccine Inoculation Route Modulates Early Immunity and Consequently Antigen-Specific Immune Response

by Pierre Rosenbaum, Pierre Rosenbaum, Nicolas Tchitchek, Nicolas Tchitchek, Candie Joly, Candie Joly, André Rodriguez Pozo, André Rodriguez Pozo, Lev Stimmer, Lev Stimmer, Sébastien Langlois, Sébastien Langlois, Hakim Hocini, Hakim Hocini, Leslie Gosse, Leslie Gosse, David Pejoski, David Pejoski, Antonio Cosma, Antonio Cosma, Anne-Sophie Beignon, Anne-Sophie Beignon, Nathalie Dereuddre-Bosquet, Nathalie Dereuddre-Bosquet, Yves Levy, Yves Levy, Roger Le Grand, Roger Le Grand, Frédéric Martinon, Frédéric Martinon
Published 2021-04-01

Optimization of HIV-1 Envelope DNA Vaccine Candidates within Three Different Animal Models, Guinea Pigs, Rabbits and Cynomolgus Macaques

by Roger Le Grand, Anders Fomsgaard, Marianne Jansson, Leo Heyndrickx, Gabriella Scarlatti, Priscilla Biswas, Guillaume Stewart-Jones, Emma Joanne Bowles, Nathalie Dereuddre-Bosquet, Frédéric Martinon, Rogier W Sanders, Mark Melchers, Tara Laura Elvang, Betina Skovgaard Andresen, Berit Grevstad, Johanna Repits, Marie Borggren, Lasse Vinner
Published 2013-07-01

Single-Stranded Nucleic Acids Regulate TLR3/4/7 Activation through Interference with Clathrin-Mediated Endocytosis

by Peter Järver, Aleksandra Dondalska, Candice Poux, AnnSofi Sandberg, Joseph Bergenstråhle, Annette E. Sköld, Nathalie Dereuddre-Bosquet, Fréderic Martinon, Sandra Pålsson, Eman Zaghloul, David Brodin, Birgitta Sander, Kim A. Lennox, Mark A. Behlke, Samir EL-Andaloussi, Janne Lehtiö, Joakim Lundeberg, Roger LeGrand, Anna-Lena Spetz
Published 2018-10-01