The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: A Hidden Markov Model Approach.

by Pascal Giehr, Charalampos Kyriakopoulos, Gabriella Ficz, Verena Wolf, Jörn Walter
Published 2016-05-01

An shRNA kinase screen identifies regulators of UHRF1 stability and activity in mouse embryonic stem cells

by Michael D. Rushton, Emily A. Saunderson, Hemalvi Patani, Michael R. Green, Gabriella Ficz
Published 2022-12-01

Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle

by John A. Halsall, Simon Andrews, Felix Krueger, Charlotte E. Rutledge, Gabriella Ficz, Wolf Reik, Bryan M. Turner
Published 2021-02-01

Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation

by Hemalvi Patani, Michael D. Rushton, Jonathan Higham, Saul A. Teijeiro, David Oxley, Pedro Cutillas, Duncan Sproul, Gabriella Ficz
Published 2020-07-01

Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.

by Cassandra R Farthing, Gabriella Ficz, Ray Kit Ng, Chun-Fung Chan, Simon Andrews, Wendy Dean, Myriam Hemberger, Wolf Reik
Published 2008-06-01

Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

by Oliver Hahn, Sebastian Grönke, Thomas M. Stubbs, Gabriella Ficz, Oliver Hendrich, Felix Krueger, Simon Andrews, Qifeng Zhang, Michael J. Wakelam, Andreas Beyer, Wolf Reik, Linda Partridge
Published 2017-03-01

Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors

by Emily A. Saunderson, Peter Stepper, Jennifer J. Gomm, Lily Hoa, Adrienne Morgan, Michael D. Allen, J. Louise Jones, John G. Gribben, Tomasz P. Jurkowski, Gabriella Ficz
Published 2017-11-01

Genome-wide Bisulfite Sequencing in Zygotes Identifies Demethylation Targets and Maps the Contribution of TET3 Oxidation

by Julian R. Peat, Wendy Dean, Stephen J. Clark, Felix Krueger, Sébastien A. Smallwood, Gabriella Ficz, Jong Kyoung Kim, John C. Marioni, Timothy A. Hore, Wolf Reik
Published 2014-12-01

Low HER2 expression in normal breast epithelium enables dedifferentiation and malignant transformation via chromatin opening

by Ateequllah Hayat, Edward P. Carter, Hamish W. King, Aysegul Ors, Aaron Doe, Saul A. Teijeiro, Sarah Charrot, Susana Godinho, Pedro Cutillas, Hisham Mohammed, Richard P. Grose, Gabriella Ficz
Published 2023-02-01

The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice

by Sabine A. S. Langie, Kerry M. Cameron, Gabriella Ficz, David Oxley, Bartłomiej Tomaszewski, Joanna P. Gorniak, Lou M. Maas, Roger W. L. Godschalk, Frederik J. van Schooten, Wolf Reik, Thomas von Zglinicki, John C. Mathers
Published 2017-02-01

Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation

by Kevin C. L. Cheng, Jennifer M. Frost, Francisco J. Sánchez-Luque, Marta García-Canãdas, Darren Taylor, Wan R. Yang, Branavy Irayanar, Swetha Sampath, Hemalvi Patani, Karl Agger, Kristian Helin, Gabriella Ficz, Kathleen H. Burns, Adam Ewing, José L. García-Pérez, Miguel R. Branco
Published 2023-10-01

Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription

by Jennifer Edelmann, Karlheinz Holzmann, Eugen Tausch, Emily A. Saunderson, Billy M. C. Jebaraj, Daniela Steinbrecher, Anna Dolnik, Tamara J. Blätte, Dan A. Landau, Jenny Saub, Sven Estenfelder, Stefan Ibach, Florence Cymbalista, Veronique Leblond, Alain Delmer, Jasmin Bahlo, Sandra Robrecht, Kirsten Fischer, Valentin Goede, Lars Bullinger, Catherine J. Wu, Daniel Mertens, Gabriella Ficz, John G. Gribben, Michael Hallek, Hartmut Döhner, Stephan Stilgenbauer
Published 2020-05-01