Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia

by Frederick J. Raal, Barbara Sjouke, G. Kees Hovingh, Barton F. Isaac
Published 2016-06-01

Low‐Density Lipoprotein Cholesterol Attributable Cardiovascular Disease Risk Is Sex Specific

by Arjen J. Cupido, Folkert W. Asselbergs, A. Floriaan Schmidt, G. Kees Hovingh
Published 2022-06-01

The PCSK9 decade

by Gilles Lambert, Barbara Sjouke, Benjamin Choque, John J.P. Kastelein, G. Kees Hovingh
Published 2012-12-01

High-density lipoprotein (HDL) particle subpopulations in heterozygous cholesteryl ester transfer protein (CETP) deficiency: maintenance of antioxidative activity.

by Sandrine Chantepie, Andrea E Bochem, M John Chapman, G Kees Hovingh, Anatol Kontush
Published 2012-01-01

Proteomic Signatures of Genetically Predicted and Pharmacologically Observed PCSK9 Inhibition

by Jordan M. Kraaijenhof, Héléne T. Cronjé, G. Kees Hovingh, Nick S. Nurmohamed, Dipender Gill, Loukas Zagkos
Published 2024-06-01

Genetic evidence implicating natriuretic peptide receptor-3 in cardiovascular disease risk: a Mendelian randomization study

by Héléne T. Cronjé, Ville Karhunen, G. Kees Hovingh, Ken Coppieters, Jens O. Lagerstedt, Michael Nyberg, Dipender Gill
Published 2023-04-01

LDL-C calculated by Friedewald, Martin-Hopkins, or NIH equation 2 versus beta-quantification: pooled alirocumab trials

by Henry N. Ginsberg, Robert S. Rosenson, G. Kees Hovingh, Alexia Letierce, Rita Samuel, Yann Poulouin, Christopher P. Cannon
Published 2022-01-01

Atorvastatin Has a Dose‐Dependent Beneficial Effect on Kidney Function and Associated Cardiovascular Outcomes: Post Hoc Analysis of 6 Double‐Blind Randomized Controlled Trials

by Liffert Vogt, Sripal Bangalore, Rana Fayyad, Shari Melamed, G. Kees Hovingh, David A. DeMicco, David D. Waters
Published 2019-05-01

Population and assay thresholds for the predictive value of lipoprotein (a) for coronary artery disease: the EPIC-Norfolk Prospective Population Study1

by Rutger Verbeek, S. Matthijs Boekholdt, Robert M. Stoekenbroek, G. Kees Hovingh, Joseph L. Witztum, Nicholas J. Wareham, Manjinder S. Sandhu, Kay-Tee Khaw, Sotirios Tsimikas
Published 2016-04-01

The role of the ABCA1 transporter and cholesterol efflux in familial hypoalphalipoproteinemia

by G. Kees Hovingh, Michel J.A. van Wijland, Alison Brownlie, Radjesh J. Bisoendial, Michael R. Hayden, John J.P. Kastelein, Albert K. Groen
Published 2003-06-01

Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups

by Marios K. Georgakis, Rainer Malik, Tom G. Richardson, Joanna M. M. Howson, Christopher D. Anderson, Stephen Burgess, G. Kees Hovingh, Martin Dichgans, Dipender Gill
Published 2022-08-01

eNOS activation by HDL is impaired in genetic CETP deficiency.

by Monica Gomaraschi, Alice Ossoli, Silvia Pozzi, Peter Nilsson, Angelo B Cefalù, Maurizio Averna, Jan Albert Kuivenhoven, G Kees Hovingh, Fabrizio Veglia, Guido Franceschini, Laura Calabresi
Published 2014-01-01

Differential DNA methylation in familial hypercholesterolemia

by Laurens F. Reeskamp, Andrea Venema, Joao P.Belo Pereira, Evgeni Levin, Max Nieuwdorp, Albert K. Groen, Joep C. Defesche, Aldo Grefhorst, Peter Henneman, G.Kees Hovingh
Published 2020-11-01

Adrenal Function in females with low plasma HDL-C due to mutations in ABCA1 and LCAT.

by Andrea E Bochem, Adriaan G Holleboom, Johannes A Romijn, Menno Hoekstra, Geesje M Dallinga, Mahdi M Motazacker, G Kees Hovingh, Jan A Kuivenhoven, Erik S G Stroes
Published 2014-01-01

Association Between Self‐Rated Medication Adherence and Adverse Cardiovascular Outcomes in Patients With Hypertension

by Shirin Ibrahim, Nick S. Nurmohamed, Didier Collard, Anouk de Weger, G. Kees Hovingh, Bert‐Jan H. van den Born, Laurens F. Reeskamp, Erik S. G. Stroes, Tom F. Brouwer
Published 2023-11-01

High density lipoprotein as a source of cholesterol for adrenal steroidogenesis: a study in individuals with low plasma HDL-C

by Andrea E. Bochem, Adriaan G. Holleboom, Johannes A. Romijn, Menno Hoekstra, Geesje M. Dallinga-Thie, Mahdi M. Motazacker, G.Kees Hovingh, Jan A. Kuivenhoven, Erik S.G. Stroes
Published 2013-06-01

Enhanced atherogenesis and altered high density lipoprotein in patients with Crohn's disease

by Sander I. van Leuven, Rachel Hezemans, Johannes H. Levels, Susan Snoek, Pieter C. Stokkers, G. Kees Hovingh, John J.P. Kastelein, Erik S. Stroes, Eric de Groot, Daan W. Hommes
Published 2007-12-01

ANGPTL3 (Angiopoietin‐Like 3) Preferentially Resides on High‐Density Lipoprotein in the Human Circulation, Affecting Its Activity

by Jordan M. Kraaijenhof, Tycho R. Tromp, Nick S. Nurmohamed, Laurens F. Reeskamp, Marije Langenkamp, Johannes H. M. Levels, S. Matthijs Boekholdt, Nicholas J. Wareham, Menno Hoekstra, Erik S. G. Stroes, G. Kees Hovingh, Aldo Grefhorst
Published 2023-11-01

Segregation of LIPG, CETP, and GALNT2 mutations in Caucasian families with extremely high HDL cholesterol.

by Ian Tietjen, G Kees Hovingh, Roshni R Singaraja, Chris Radomski, Amina Barhdadi, Jason McEwen, Elden Chan, Maryanne Mattice, Annick Legendre, Patrick L Franchini, Marie-Pierre Dubé, John J P Kastelein, Michael R Hayden
Published 2012-01-01

High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins

by Josefien W. Hommes, Rachel M. Kratofil, Sigrid Wahlen, Carla J. C. de Haas, Reeni B. Hildebrand, G. Kees Hovingh, Micheal Otto, Miranda van Eck, Menno Hoekstra, Suzanne J. A. Korporaal, Bas G. J. Surewaard
Published 2021-07-01