TwoStepCisMR: A Novel Method and R Package for Attenuating Bias in <i>cis</i>-Mendelian Randomization Analyses

by Benjamin Woolf, Loukas Zagkos, Dipender Gill
Published 2022-08-01

Exploring the contribution of lifestyle to the impact of education on the risk of cancer through Mendelian randomization analysis

by Loukas Zagkos, Alexander Schwinges, Hasnat A. Amin, Terry Dovey, Fotios Drenos
Published 2024-03-01

Cerebrospinal and Brain Proteins Implicated in Neuropsychiatric and Risk Factor Traits: Evidence from Mendelian Randomization

by Roxane de La Harpe, Loukas Zagkos, Dipender Gill, Héléne T. Cronjé, Ville Karhunen
Published 2024-01-01

Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization

by Benjamin Woolf, Héléne T. Cronjé, Loukas Zagkos, Stephen Burgess, Dipender Gill, Susanna C. Larsson
Published 2023-08-01

MRSamePopTest: introducing a simple falsification test for the two-sample mendelian randomisation ‘same population’ assumption

by Benjamin Woolf, Amy Mason, Loukas Zagkos, Hannah Sallis, Marcus R. Munafò, Dipender Gill
Published 2024-01-01

Proteomic Signatures of Genetically Predicted and Pharmacologically Observed PCSK9 Inhibition

by Jordan M. Kraaijenhof, Héléne T. Cronjé, G. Kees Hovingh, Nick S. Nurmohamed, Dipender Gill, Loukas Zagkos
Published 2024-06-01

Using genetics to investigate the association between lanosterol and cataract

by Munisa Hashimi, Hasnat A. Amin, Loukas Zagkos, Alexander C. Day, Alexander C. Day, Fotios Drenos
Published 2024-02-01

The citrate transporter SLC13A5 as a therapeutic target for kidney disease: evidence from Mendelian randomization to inform drug development

by Dipender Gill, Loukas Zagkos, Rubinder Gill, Thomas Benzing, Jens Jordan, Andreas L. Birkenfeld, Stephen Burgess, Grit Zahn
Published 2023-12-01

Cerebrospinal Fluid C1-Esterase Inhibitor and Tie-1 Levels Affect Cognitive Performance: Evidence from Proteome-Wide Mendelian Randomization

by Loukas Zagkos, Marie-Joe Dib, Héléne T. Cronjé, Paul Elliott, Abbas Dehghan, Ioanna Tzoulaki, Dipender Gill, Iyas Daghlas
Published 2024-01-01

Caffeine Intake, Plasma Caffeine Level, and Kidney Function: A Mendelian Randomization Study

by Alice Giontella, Roxane de La Harpe, Héléne T. Cronje, Loukas Zagkos, Benjamin Woolf, Susanna C. Larsson, Dipender Gill
Published 2023-10-01

Associations of Genetically Predicted Vitamin B₁₂ Status across the Phenome

by Marie-Joe Dib, Kourosh R. Ahmadi, Loukas Zagkos, Dipender Gill, Brooke Morris, Paul Elliott, Abbas Dehghan, Ioanna Tzoulaki
Published 2022-11-01

Associations of genetically predicted fatty acid levels across the phenome: A mendelian randomisation study.

by Loukas Zagkos, Marie-Joe Dib, Rui Pinto, Dipender Gill, Fotios Koskeridis, Fotios Drenos, Georgios Markozannes, Paul Elliott, Verena Zuber, Kostas Tsilidis, Abbas Dehghan, Ioanna Tzoulaki
Published 2022-12-01

Genetic investigation into the broad health implications of caffeine: evidence from phenome-wide, proteome-wide and metabolome-wide Mendelian randomization

by Loukas Zagkos, Héléne T. Cronjé, Benjamin Woolf, Roxane de La Harpe, Stephen Burgess, Christos S. Mantzoros, Paul Elliott, Shuai Yuan, Susanna C. Larsson, Ioanna Tzoulaki, Dipender Gill
Published 2024-02-01

Associations of genetically predicted fatty acid levels across the phenome: A mendelian randomisation study

by Loukas Zagkos, Marie-Joe Dib, Rui Pinto, Dipender Gill, Fotios Koskeridis, Fotios Drenos, Georgios Markozannes, Paul Elliott, Verena Zuber, Kostas Tsilidis, Abbas Dehghan, Ioanna Tzoulaki
Published 2022-12-01

Appraising the Causal Role of Risk Factors in Coronary Artery Disease and Stroke: A Systematic Review of Mendelian Randomization Studies

by Andrea N. Georgiou, Loukas Zagkos, Georgios Markozannes, Christos V. Chalitsios, Alexandros G. Asimakopoulos, Wei Xu, Lijuan Wang, Ines Mesa‐Eguiagaray, Xuan Zhou, Eleni M. Loizidou, Nikolaos Kretsavos, Evropi Theodoratou, Dipender Gill, Stephen Burgess, Evangelos Evangelou, Konstantinos K. Tsilidis, Ioanna Tzoulaki
Published 2023-10-01

Proteomic Associations of Adverse Outcomes in Human Heart Failure

by Marie‐Joe Dib, Michael G. Levin, Lei Zhao, Ahmed Diab, Zhaoqing Wang, Christina Ebert, Oday Salman, Joe David Azzo, Sushrima Gan, Payman Zamani, Jordana B. Cohen, Dipender Gill, Stephen Burgess, Loukas Zagkos, Vanessa van Empel, A. Mark Richards, Rob Doughty, Ernst R. Rietzschel, Karl Kammerhoff, Erika Kvikstad, Joseph Maranville, Peter Schafer, Dietmar A. Seiffert, Francisco Ramirez‐Valle, David A. Gordon, Ching‐Pin Chang, Ali Javaheri, Douglas L. Mann, Thomas P. Cappola, Julio A. Chirinos
Published 2024-03-01