Sirtuin 3 and Uncouplin Protein 2, the Missing Link Between Genetics, Metabolism, and Pulmonary Arterial Hypertension

by Annie C. Lajoie, François Potus
Published 2021-12-01

COVID-19 and the pulmonary vasculature

by Steeve Provencher, François Potus, Sébastien Bonnet
Published 2020-06-01

Right Ventricle and Epigenetics: A Systematic Review

by Victoria Toro, Naomie Jutras-Beaudoin, Olivier Boucherat, Sebastien Bonnet, Steeve Provencher, François Potus
Published 2023-11-01

Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiog...

by Francois Potus, Charles Colin Thomas Hindmarch, Kimberly J. Dunham-Snary, Jeff Stafford, Stephen L. Archer
Published 2018-09-01

Recent advancements in pulmonary arterial hypertension and right heart failure research: overview of selected abstracts from ATS2020 and emerging COVID-19 research

by Francois Potus, Andrea L. Frump, Soban Umar, Rebecca R. Vanderpool, Imad Al Ghouleh, Yen-Chun Lai
Published 2021-08-01

Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension

by Lian Tian, Francois Potus, Danchen Wu, Asish Dasgupta, Kuang-Hueih Chen, Jeffrey Mewburn, Patricia Lima, Stephen L. Archer
Published 2018-07-01

Dual ET/ET blockade with macitentan improves both vascular remodeling and angiogenesis in pulmonary arterial hypertension

by Valerie Nadeau, Francois Potus, Olivier Boucherat, Renee Paradis, Eve Tremblay, Marc Iglarz, Roxane Paulin, Sebastien Bonnet, Steeve Provencher
Published 2017-11-01

Neutrophil-Lymphocyte Ratio as an Independent Predictor of Survival in Pulmonary Arterial Hypertension: An Exploratory Study

by Naomie Jutras-Beaudoin, BSc, Victoria Toro, MSc, Annie Christine Lajoie, MD, Sandra Breuils-Bonnet, MSc, Roxane Paulin, PhD, François Potus, PhD
Published 2022-04-01

Prognostic Significance of Proteomics‐Discovered Circulating Inflammatory Biomarkers in Patients With Pulmonary Arterial Hypertension

by Tetsuro Yokokawa, Olivier Boucherat, Sandra Martineau, Sarah‐Eve Lemay, Sandra Breuils‐Bonnet, Vinod Krishna, Shanker Kalyana‐Sundaram, Jey Jeyaseelan, François Potus, Sébastien Bonnet, Steeve Provencher
Published 2024-06-01

An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats

by Charles Colin Thomas Hindmarch, Lian Tian, Ping Yu Xiong, Francois Potus, Rachel Emily Teresa Bentley, Ruaa Al-Qazazi, Kurt W. Prins, Stephen L. Archer, Stephen L. Archer
Published 2022-11-01

Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension

by Sasha Z. Prisco, Lauren Rose, Francois Potus, Lian Tian, Danchen Wu, Lynn Hartweck, Ruaa Al-Qazazi, Monica Neuber-Hess, Megan Eklund, Steven Hsu, Thenappan Thenappan, Stephen L. Archer, Kurt W. Prins
Published 2020-10-01

HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension

by Olivier Boucherat, Sophie Chabot, Roxane Paulin, Isabelle Trinh, Alice Bourgeois, François Potus, Marie-Claude Lampron, Caroline Lambert, Sandra Breuils-Bonnet, Valérie Nadeau, Renée Paradis, Elena A. Goncharova, Steeve Provencher, Sébastien Bonnet
Published 2017-07-01

Biventricular Increases in Mitochondrial Fission Mediator (MiD51) and Proglycolytic Pyruvate Kinase (PKM2) Isoform in Experimental Group 2 Pulmonary Hypertension-Novel Mitochondria...

by Ping Yu Xiong, Ping Yu Xiong, Lian Tian, Kimberly J. Dunham-Snary, Kuang-Hueih Chen, Jeffrey D. Mewburn, Monica Neuber-Hess, Ashley Martin, Asish Dasgupta, Francois Potus, Stephen L. Archer, Stephen L. Archer
Published 2019-01-01

Implication of EZH2 in the Pro-Proliferative and Apoptosis-Resistant Phenotype of Pulmonary Artery Smooth Muscle Cells in PAH: A Transcriptomic and Proteomic Approach

by Karima Habbout, Junichi Omura, Charifa Awada, Alice Bourgeois, Yann Grobs, Vinod Krishna, Sandra Breuils-Bonnet, Eve Tremblay, Ghada Mkannez, Sandra Martineau, Valérie Nadeau, Florence Roux-Dalvai, Mark Orcholski, Jey Jeyaseelan, David Gutstein, François Potus, Steeve Provencher, Sébastien Bonnet, Roxane Paulin, Olivier Boucherat
Published 2021-03-01