Dual ET/ET blockade with macitentan improves both vascular remodeling and angiogenesis in pulmonary arterial hypertension

by Valerie Nadeau, Francois Potus, Olivier Boucherat, Renee Paradis, Eve Tremblay, Marc Iglarz, Roxane Paulin, Sebastien Bonnet, Steeve Provencher
Published 2017-11-01

Selective improvement of pulmonary arterial hypertension with a dual ET/ET receptors antagonist in the apolipoprotein E model of PAH and atherosclerosis

by Lewis Renshall, Nadine Arnold, Laura West, Adam Braithwaite, Josephine Pickworth, Rachel Walker, Mabruka Alfaidi, Janet Chamberlain, Helen Casbolt, A.A. Roger Thompson, Cathy Holt, Marc Iglarz, Sheila Francis, Allan Lawrie
Published 2018-01-01

Effects of macitentan and tadalafil monotherapy or their combination on the right ventricle and plasma metabolites in pulmonary hypertensive rats

by Argen Mamazhakypov, Astrid Weiß, Sven Zukunft, Akylbek Sydykov, Baktybek Kojonazarov, Jochen Wilhelm, Christina Vroom, Aleksandar Petrovic, Djuro Kosanovic, Norbert Weissmann, Werner Seeger, Ingrid Fleming, Marc Iglarz, Friedrich Grimminger, Hossein A. Ghofrani, Soni S. Pullamsetti, Ralph T. Schermuly
Published 2020-11-01