Patient-Derived Orthotopic Xenograft Models of Pediatric Brain Tumors: In a Mature Phase or Still in Its Infancy?

by Eva Hermans, Esther Hulleman, Esther Hulleman
Published 2020-01-01

Clustered regularly interspaced short palindromic repeats screens in pediatric tumours: A review

by Madelaine G. vanMackelenbergh, Dennis S. Metselaar, Michaël H. Meel, Esther Hulleman
Published 2022-12-01

Pyruvate kinase M2 and prednisolone resistance in acute lymphoblastic leukemia

by Esther Hulleman, Mathilde JC Broekhuis, Rob Pieters, Monique L Den Boer
Published 2009-09-01

An efficient method for the transduction of primary pediatric glioma neurospheres

by Michaël H. Meel, Dennis S. Metselaar, Piotr Waranecki, Gertjan J.L. Kaspers, Esther Hulleman
Published 2018-01-01

Defining tumor-associated vascular heterogeneity in pediatric high-grade and diffuse midline gliomas

by Xin Wei, Michaël H. Meel, Marjolein Breur, Marianna Bugiani, Esther Hulleman, Timothy N. Phoenix
Published 2021-08-01

OV Modulators of the Paediatric Brain TIME: Current Status, Combination Strategies, Limitations and Future Directions

by Konstantinos Vazaios, Ronja E. van Berkum, Friso G. Calkoen, Jasper van der Lugt, Esther Hulleman
Published 2024-05-01

Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin

by Dennis S. Metselaar, Michaël H. Meel, Bente Benedict, Piotr Waranecki, Jan Koster, Gertjan J.L. Kaspers, Esther Hulleman
Published 2019-12-01

Radiosensitization in Pediatric High-Grade Glioma: Targets, Resistance and Developments

by Dennis S. Metselaar, Dennis S. Metselaar, Aimée du Chatinier, Iris Stuiver, Gertjan J. L. Kaspers, Gertjan J. L. Kaspers, Esther Hulleman
Published 2021-04-01

Imaged-guided focused ultrasound in combination with various formulations of doxorubicin for the treatment of diffuse intrinsic pontine glioma

by Rianne Haumann, John I. Bianco, Piotr M. Waranecki, Pieter J. Gaillard, Gert Storm, Mario Ries, Dannis G. van Vuurden, Gertjan J. L. Kaspers, Esther Hulleman
Published 2022-04-01

AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma

by Dennis S. Metselaar, Aimée du Chatinier, Michaël H. Meel, Giovanna ter Huizen, Piotr Waranecki, Joshua R. Goulding, Marianna Bugiani, Jan Koster, Gertjan J.L. Kaspers, Esther Hulleman
Published 2022-06-01

The neurovascular unit in diffuse intrinsic pontine gliomas

by Fatma E. El-Khouly, Rianne Haumann, Marjolein Breur, Sophie E.M. Veldhuijzen van Zanten, Gertjan J.L. Kaspers, N. Harry Hendrikse, Esther Hulleman, Dannis G. van Vuurden, Marianna Bugiani
Published 2021-07-01

Tocilizumab for the fifth progression of cystic childhood craniopharyngioma—a case report

by Evelien de Vos-Kerkhof, Dennis R. Buis, Maarten H. Lequin, Carlien A. Bennebroek, Eleonora Aronica, Esther Hulleman, Nitash Zwaveling-Soonawala, Hanneke M. van Santen, Antoinette Y. N. Schouten-van Meeteren
Published 2023-10-01

IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma.

by Noah E Berlow, Matthew N Svalina, Michael J Quist, Teagan P Settelmeyer, Viktor Zherebitskiy, Mari Kogiso, Lin Qi, Yuchen Du, Cynthia E Hawkins, Esther Hulleman, Xiao-Nan Li, Sakir H Gultekin, Charles Keller
Published 2018-01-01

In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma.

by Susanna J E Veringa, Dennis Biesmans, Dannis G van Vuurden, Marc H A Jansen, Laurine E Wedekind, Ilona Horsman, Pieter Wesseling, William Peter Vandertop, David P Noske, GertJan J L Kaspers, Esther Hulleman
Published 2013-01-01

Effective Drug Delivery in Diffuse Intrinsic Pontine Glioma: A Theoretical Model to Identify Potential Candidates

by Fatma E. El-Khouly, Fatma E. El-Khouly, Dannis G. van Vuurden, Thom Stroink, Esther Hulleman, Gertjan J. L. Kaspers, Gertjan J. L. Kaspers, N. Harry Hendrikse, N. Harry Hendrikse, Sophie E. M. Veldhuijzen van Zanten
Published 2017-10-01

Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG

by Ilango Balakrishnan, Etienne Danis, Angela Pierce, Krishna Madhavan, Dong Wang, Nathan Dahl, Bridget Sanford, Diane K. Birks, Nate Davidson, Dennis S. Metselaar, Michaël Hananja Meel, Rakeb Lemma, Andrew Donson, Trinka Vijmasi, Hiroaki Katagi, Ismail Sola, Susan Fosmire, Irina Alimova, Jenna Steiner, Ahmed Gilani, Esther Hulleman, Natalie J. Serkova, Rintaro Hashizume, Cynthia Hawkins, Angel M. Carcaboso, Nalin Gupta, Michelle Monje, Nada Jabado, Kenneth Jones, Nicholas Foreman, Adam Green, Rajeev Vibhakar, Sujatha Venkataraman
Published 2020-10-01

Targeting pediatric cancers via T-cell recognition of the monomorphic MHC class I-related protein MR1

by Aimee du Chatinier, Zsolt Sebestyen, Jürgen Kuball, Stefan Nierkens, Anja Krippner-Heidenreich, Yuyan Lu, Ana P Lopes, Ester Dunnebach, Denise A M H van den Beemt, Sebastiaan van Heesch, Annelisa M. Cornel, Loutje van der Sman, Jip T van Dinter, Marta Arrabito, Marliek van Hoesel, Thomas A Kluiver, Noël M M Dautzenberg, Linde Dekker, Jorik M van Rijn, Juliane L Buhl, Farnaz Barneh, Luca Lo Nigro, Esther Hulleman, Jarno Drost, Olaf T Heidenreich, Weng Chuan Peng
Published 2024-03-01

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma

by Walderik W. Zomerman, Sabine L.A. Plasschaert, Siobhan Conroy, Frank J. Scherpen, Tiny G.J. Meeuwsen-de Boer, Harm J. Lourens, Sergi Guerrero Llobet, Marlinde J. Smit, Lorian Slagter-Menkema, Annika Seitz, Corrie E.M. Gidding, Esther Hulleman, Pieter Wesseling, Lisethe Meijer, Leon C. van Kempen, Anke van den Berg, Daniël O. Warmerdam, Frank A.E. Kruyt, Floris Foijer, Marcel A.T.M. van Vugt, Wilfred F.A. den Dunnen, Eelco W. Hoving, Victor Guryev, Eveline S.J.M. de Bont, Sophia W.M. Bruggeman
Published 2018-03-01

Identification of temozolomide resistance factors in glioblastoma via integrative miRNA/mRNA regulatory network analysis

by Hiddingh, Lotte, Raktoe, Rajiv S., Jeuken, Judith, Hulleman, Esther, Noske, David P., Kaspers, Gertjan J. L., Vandertop, W. Peter, Wesseling, Pieter, Wurdinger, Thomas
Published 2014

Trimethylation of H3K27 during human cerebellar development in relation to medulloblastoma

by Mir, Shahryar E., Smits, Michiel, Biesmans, Dennis, Julsing, Machteld, Bugiani, Marianna, Aronica, Eleonora, Kaspers, Gertjan J.L., Cloos, Jacqueline, Würdinger, Thomas, Hulleman, Esther
Published 2017