RNA Antisense Purification (RAP) for Mapping RNA Interactions with Chromatin

by Engreitz, Jesse Michael, Lander, Eric Steven, Guttman, Mitchell
Published 2017

The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome

by Engreitz, Jesse Michael, Pandya-Jones, Amy, McDonel, Patrick, Shishkin, Alexander, Sirokman, Klara, Surka, Christine, Kadri, Sabah, Xing, Jeffrey, Goren, Alon, Plath, Kathrin, Guttman, Mitchell, Lander, Eric Steven
Published 2014

RNA-RNA Interactions Enable Specific Targeting of Noncoding RNAs to Nascent Pre-mRNAs and Chromatin Sites

by Sirokman, Klara, McDonel, Patrick, Shishkin, Alexander A., Surka, Christine, Russell, Pamela, Chow, Amy Y., Guttman, Mitchell, Lander, Eric Steven, Engreitz, Jesse Michael, Grossman, Sharon Rachel
Published 2017

Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA

by Schwartz, Schraga, Bernstein, Douglas A., Mumbach, Maxwell R., Jovanovic, Marko, Herbst, Rebecca H., León-Ricardo, Brian X., Guttman, Mitchell, Satija, Rahul, Fink, Gerald, Engreitz, Jesse Michael, Lander, Eric Steven, Regev, Aviv
Published 2017

Recurrent and functional regulatory mutations in breast cancer

by Parasuraman, Prasanna, Tiao, Grace, Kim, Jaegil, Taylor-Weiner, Amaro, Rodriguez-Cuevas, Sergio, Rosenberg, Mara, Hess, Julian, Stewart, Chip, Maruvka, Yosef E., Stojanov, Petar, Seepo, Sara, Cibulskis, Carrie, Tracy, Adam, Pugh, Trevor J., Lee, Jesse, Zheng, Zongli, Ellisen, Leif W., Iafrate, A. John, Boehm, Jesse S., Baselga, Jose, Hidalgo-Miranda, Alfredo, Shioda, Toshi, Bernards, Andre, Engreitz, Jesse Michael, Lander, Eric Steven, Rheinbay, Esther, Lawrence, Michael, Cortes, Maria, Gabriel, Stacey, Golub, Todd, Getz, Gad Asher, Meyerson, Matthew L.
Published 2018

Systematic dissection of genomic features determining transcription factor binding and enhancer function

by Zhang, Xiaolan, Wang, Li, Melnikov, Alexandre, Rogov, Peter, Tewhey, Ryan, Isakova, Alina, Deplancke, Bart, Bernstein, Bradley E., Mikkelsen, Tarjei S., Grossman, Sharon Rachel, Engreitz, Jesse Michael, Lander, Eric Steven
Published 2017

Three-Dimensional Genome Architecture Influences Partner Selection for Chromosomal Translocations in Human Disease

by Engreitz, Jesse Michael, Agarwala, Vineeta, Mirny, Leonid A.
Published 2013

Local regulation of gene expression by lncRNA promoters, transcription and splicing

by Haines, Jenna E., Perez, Elizabeth M., Munson, Glen, Kane, Michael, McDonel, Patrick E., Guttman, Mitchell, Engreitz, Jesse Michael, Chen, Jennifer, Lander, Eric Steven
Published 2018

The Lin28/let-7 Axis Regulates Glucose Metabolism

by Zhu, Hao, Shyh-Chang, Ng, Segrè, Ayellet V., Shinoda, Gen, Shah, Samar P., Einhorn, William S., Takeuchi, Ayumu, Engreitz, Jesse Michael, Hagan, John P., Kharas, Michael G., Urbach, Achia, Thornton, James E., Triboulet, Robinson, Gregory, Richard I., Altshuler, David, Daley, George Q.
Published 2014

Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

by Verdine, Vanessa K., Aguet, Francois, Fulco, Charles P., Tseng, Yuen-Yi, Boehm, Jesse S., Joung, Julia, Engreitz, Jesse Michael, Konermann, Silvana M, Gootenberg, Jonathan S, Sanjana, Neville E, Wright, Jason, Yoon, Charles, Lander, Eric Steven, Zhang, Feng, Abudayyeh, Omar O.
Published 2018

Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

by Cochran, Jennifer R, Moynihan, Kelly Dare, Opel, Cary Francis, Szeto, Gregory, Tzeng, Alice, Zhu, Eric Franklin, Engreitz, Jesse Michael, Williams, Robert T., Rakhra, Kavya, Zhang, Michael H, Rothschilds, Adrienne Marie, Kumari, Sudha, Kelly, Ryan Lewis, Kwan, Byron Hua, Abraham, Wuhbet, Hu, Kevin, Mehta, Naveen, Kauke, Monique Jacqueline, Suh, Heikyung, Lauffenburger, Douglas A, Wittrup, Karl Dane, Irvine, Darrell J
Published 2017

CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data

by Hsu, Jonathan Y., Fulco, Charles P., Farouni, Rick, Clement, Kendell, Engreitz, Jesse Michael, Lander, Eric Steven, Pinello, Luca
Published 2020

Three-Dimensional Genome Architecture Influences Partner Selection for Chromosomal Translocations in Human Disease

by Engreitz, Jesse Michael, Agarwala, Vineeta, Mirny, Leonid Alex
Published 2014

Topological organization of multi-chromosomal regions by Firre

by Hacisuleyman, Ezgi, Trapnell, Cole, Williams, Adam, Henao-Mejia, Jorge, Sun, Lei, McClanahan, Patrick, Hendrickson, David G., Sauvageau, Martin, Kelley, David R., Morse, Michael, Engreitz, Jesse Michael, Guttman, Mitchell, Flavell, Richard A., Raj, Arjun, Rinn, John L., Goff, Loyal, Lander, Eric Steven, Lodish, Harvey F
Published 2015

Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations

by Fulco, Charles P., Nasser, Joseph, Jones, Thouis R., Munson, Glen, Bergman, Drew T., Subramanian, Vidya, Grossman, Sharon Rachel, Anyoha, Rockwell, Doughty, Benjamin R., Patwardhan, Tejal A., Nguyen, Tung Hoang, Kane, Michael A., Perez, Elizabeth M., Durand, Neva C., Lareau, Caleb A., Stamenova, Elena K., Aiden, Erez Lieberman, Lander, Eric Steven, Engreitz, Jesse Michael
Published 2021

Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

by Khajuria, Rajiv K., Munschauer, Mathias, Ulirsch, Jacob C., Fiorini, Claudia, Ludwig, Leif S., McFarland, Sean K., Abdulhay, Nour J., Specht, Harrison, Keshishian, Hasmik, Mani, Denkanikota R, Jovanovic, Marko, Ellis, Steven R., Fulco, Charles P., Engreitz, Jesse Michael, Schutz, Sabina, Lian, John, Gripp, Karen W., Weinberg, Olga K., Pinkus, Geraldine S., Gehrke, Lee, Regev, Aviv, Lander, Eric Steven, Gazda, Hanna T., Lee, Winston Y., Panse, Vikram G., Sankaran, Vijay G., Carr, Steven A
Published 2019

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

by Munschauer, Mathias, Nguyen, Celina T., Sirokman, Klara, Hartigan, Christina R., Hogstrom, Larson, Engreitz, Jesse Michael, Ulirsch, Jacob C., Fulco, Charles P., Subramanian, Vidya, Chen, Jenny, Schenone, Monica, Guttman, Mitchell, Carr, Steven A, Lander, Eric Steven
Published 2020