Exploiting the circuit breaker cancer evolution model in human clear cell renal cell carcinoma

by James J. Hsieh, Emily H. Cheng
Published 2020-06-01

BAK regulates catalase release from peroxisomes

by Yukio Fujiki, Non Miyata, Satoru Mukai, Kanji Okumoto, Emily H. Cheng
Published 2017-05-01

SWI/SNF tumor suppressor gene PBRM1/BAF180 in human clear cell kidney cancer

by Amrita M. Nargund, Hatice U. Osmanbeyoglu, Emily H. Cheng, James J. Hsieh
Published 2017-07-01

Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis

by Nadege Gitego, Bogos Agianian, Oi Wei Mak, Vasantha Kumar MV, Emily H. Cheng, Evripidis Gavathiotis
Published 2023-12-01

Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA

by Hidetaka Niizuma, Adam C. Searleman, Shugaku Takeda, Scott A. Armstrong, Christopher Y. Park, Emily H. Cheng, James J. Hsieh
Published 2021-08-01

A Chemical Glycoproteomics Platform Reveals O-GlcNAcylation of Mitochondrial Voltage-Dependent Anion Channel 2

by Krishnan K. Palaniappan, Matthew J. Hangauer, Timothy J. Smith, Brian P. Smart, Austin A. Pitcher, Emily H. Cheng, Carolyn R. Bertozzi, Michael Boyce
Published 2013-10-01

A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway.

by Sebastián Zamorano, Diego Rojas-Rivera, Fernanda Lisbona, Valentina Parra, Felipe A Court, Rosario Villegas, Emily H Cheng, Stanley J Korsmeyer, Sergio Lavandero, Claudio Hetz
Published 2012-01-01

SETD2 regulates chromatin accessibility and transcription to suppress lung tumorigenesis

by Yuchen Xie, Merve Sahin, Toru Wakamatsu, Akane Inoue-Yamauchi, Wanming Zhao, Song Han, Amrita M. Nargund, Shaoyuan Yang, Yang Lyu, James J. Hsieh, Christina S. Leslie, Emily H. Cheng
Published 2023-02-01

ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival

by Gary X. Wang, Ho-Chou Tu, Yiyu Dong, Anders Jacobsen Skanderup, Yufeng Wang, Shugaku Takeda, Yogesh Tengarai Ganesan, Song Han, Han Liu, James J. Hsieh, Emily H. Cheng
Published 2017-12-01

Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy

by Akane Inoue-Yamauchi, Paul S. Jeng, Kwanghee Kim, Hui-Chen Chen, Song Han, Yogesh Tengarai Ganesan, Kota Ishizawa, Sylvia Jebiwott, Yiyu Dong, Maria C. Pietanza, Matthew D. Hellmann, Mark G. Kris, James J. Hsieh, Emily H. Cheng
Published 2017-07-01

Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy

by Daniel D. Shapiro, Niki Millward Zacharias, Durga N. Tripathi, Menuka Karki, Jean‐Philippe Bertocchio, Melinda Soeung, Rong He, Mary E. Westerman, Jianjun Gao, Priya Rao, Truong N. A. Lam, Eric Jonasch, Luigi Perelli, Emily H. Cheng, Alessandro Carugo, Timothy P. Heffernan, Cheryl L. Walker, Giannicola Genovese, Nizar M. Tannir, Jose A. Karam, Pavlos Msaouel
Published 2023-05-01

The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma

by Amrita M. Nargund, Can G. Pham, Yiyu Dong, Patricia I. Wang, Hatice U. Osmangeyoglu, Yuchen Xie, Omer Aras, Song Han, Toshinao Oyama, Shugaku Takeda, Chelsea E. Ray, Zhenghong Dong, Mathieu Berge, A. Ari Hakimi, Sebastien Monette, Carl L. Lekaye, Jason A. Koutcher, Christina S. Leslie, Chad J. Creighton, Nils Weinhold, William Lee, Satish K. Tickoo, Zhong Wang, Emily H. Cheng, James J. Hsieh
Published 2017-03-01

Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets

by Ying-Bei Chen, Jianing Xu, Anders Jacobsen Skanderup, Yiyu Dong, A. Rose Brannon, Lu Wang, Helen H. Won, Patricia I. Wang, Gouri J. Nanjangud, Achim A. Jungbluth, Wei Li, Virginia Ojeda, A. Ari Hakimi, Martin H. Voss, Nikolaus Schultz, Robert J. Motzer, Paul Russo, Emily H. Cheng, Filippo G. Giancotti, William Lee, Michael F. Berger, Satish K. Tickoo, Victor E. Reuter, James J. Hsieh
Published 2016-10-01

Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma

by Jianing Xu, Ed Reznik, Ho-Joon Lee, Gunes Gundem, Philip Jonsson, Judy Sarungbam, Anna Bialik, Francisco Sanchez-Vega, Chad J Creighton, Jake Hoekstra, Li Zhang, Peter Sajjakulnukit, Daniel Kremer, Zachary Tolstyka, Jozefina Casuscelli, Steve Stirdivant, Jie Tang, Nikolaus Schultz, Paul Jeng, Yiyu Dong, Wenjing Su, Emily H Cheng, Paul Russo, Jonathan A Coleman, Elli Papaemmanuil, Ying-Bei Chen, Victor E Reuter, Chris Sander, Scott R Kennedy, James J Hsieh, Costas A Lyssiotis, Satish K Tickoo, A Ari Hakimi
Published 2019-03-01

A BAX/BAK and Cyclophilin D-Independent Intrinsic Apoptosis Pathway

by Zamorano, Sebastián, Rojas-Rivera, Diego, Lisbona, Fernanda, Parra, Valentina, Court, Felipe A., Villegas, Rosario, Cheng, Emily H., Korsmeyer, Stanley J., Lavandero, Sergio, Hetz, Claudio
Published 2013