Craniofacial genetics: Where have we been and where are we going?

by Seth M Weinberg, Robert Cornell, Elizabeth J Leslie
Published 2018-06-01

Genetic factors influencing risk to orofacial clefts: today’s challenges and tomorrow’s opportunities [version 1; referees: 2 approved]

by Terri H. Beaty, Mary L. Marazita, Elizabeth J. Leslie
Published 2016-11-01

Identification of common non-coding variants at 1p22 that are functional for non-syndromic orofacial clefting

by Huan Liu, Elizabeth J. Leslie, Jenna C. Carlson, Terri H. Beaty, Mary L. Marazita, Andrew C. Lidral, Robert A. Cornell
Published 2017-03-01

Genome-wide association study of facial morphology reveals novel associations with FREM1 and PARK2.

by Myoung Keun Lee, John R Shaffer, Elizabeth J Leslie, Ekaterina Orlova, Jenna C Carlson, Eleanor Feingold, Mary L Marazita, Seth M Weinberg
Published 2017-01-01

Caries Experience Differs between Females and Males across Age Groups in Northern Appalachia

by John R. Shaffer, Elizabeth J. Leslie, Eleanor Feingold, Manika Govil, Daniel W. McNeil, Richard J. Crout, Robert J. Weyant, Mary L. Marazita
Published 2015-01-01

Investigating gene functions and single-cell expression profiles of de novo variants in orofacial clefts

by Toshiyuki Itai, Fangfang Yan, Andi Liu, Yulin Dai, Chihiro Iwaya, Sarah W. Curtis, Elizabeth J. Leslie, Lukas M. Simon, Peilin Jia, Xiangning Chen, Junichi Iwata, Zhongming Zhao
Published 2024-07-01

Integrative analysis of transcriptome dynamics during human craniofacial development identifies candidate disease genes

by Tara N. Yankee, Sungryong Oh, Emma Wentworth Winchester, Andrea Wilderman, Kelsey Robinson, Tia Gordon, Jill A. Rosenfeld, Jennifer VanOudenhove, Daryl A. Scott, Elizabeth J. Leslie, Justin Cotney
Published 2023-08-01

Pleiotropy method reveals genetic overlap between orofacial clefts at multiple novel loci from GWAS of multi-ethnic trios.

by Debashree Ray, Sowmya Venkataraghavan, Wanying Zhang, Elizabeth J Leslie, Jacqueline B Hetmanski, Seth M Weinberg, Jeffrey C Murray, Mary L Marazita, Ingo Ruczinski, Margaret A Taub, Terri H Beaty
Published 2021-07-01

Individuals with nonsyndromic orofacial clefts have increased asymmetry of fingerprint patterns.

by Katherine Neiswanger, Nandita Mukhopadhyay, Shwetha Rajagopalan, Elizabeth J Leslie, Carla A Sanchez, Jacqueline T Hecht, Iêda M Orioli, Fernando A Poletta, Javier Enríquez de Salamanca, Seth M Weinberg, Mary L Marazita
Published 2020-01-01

A LINE-1 insertion in DLX6 is responsible for cleft palate and mandibular abnormalities in a canine model of Pierre Robin sequence.

by Zena T Wolf, Elizabeth J Leslie, Boaz Arzi, Kartika Jayashankar, Nili Karmi, Zhonglin Jia, Douglas J Rowland, Amy Young, Noa Safra, Saundra Sliskovic, Jeffrey C Murray, Claire M Wade, Danika L Bannasch
Published 2014-04-01

Genome-wide Interaction Study Implicates VGLL2 and Alcohol Exposure and PRL and Smoking in Orofacial Cleft Risk

by Jenna C. Carlson, John R. Shaffer, Fred Deleyiannis, Jacqueline T. Hecht, George L. Wehby, Kaare Christensen, Eleanor Feingold, Eleanor Feingold, Seth M. Weinberg, Seth M. Weinberg, Mary L. Marazita, Mary L. Marazita, Elizabeth J. Leslie
Published 2022-02-01

Detecting Gene-Environment Interaction for Maternal Exposures Using Case-Parent Trios Ascertained Through a Case With Non-Syndromic Orofacial Cleft

by Wanying Zhang, Sowmya Venkataraghavan, Jacqueline B. Hetmanski, Elizabeth J. Leslie, Mary L. Marazita, Mary L. Marazita, Eleanor Feingold, Seth M. Weinberg, Seth M. Weinberg, Ingo Ruczinski, Margaret A. Taub, Alan F. Scott, Debashree Ray, Terri H. Beaty
Published 2021-04-01

Integrative approaches generate insights into the architecture of non-syndromic cleft lip with or without cleft palate

by Julia Welzenbach, Nigel L. Hammond, Miloš Nikolić, Frederic Thieme, Nina Ishorst, Elizabeth J. Leslie, Seth M. Weinberg, Terri H. Beaty, Mary L. Marazita, Elisabeth Mangold, Michael Knapp, Justin Cotney, Alvaro Rada-Iglesias, Michael J. Dixon, Kerstin U. Ludwig
Published 2021-07-01

The PAX1 locus at 20p11 is a potential genetic modifier for bilateral cleft lip

by Sarah W. Curtis, Daniel Chang, Myoung Keun Lee, John R. Shaffer, Karlijne Indencleef, Michael P. Epstein, David J. Cutler, Jeffrey C. Murray, Eleanor Feingold, Terri H. Beaty, Peter Claes, Seth M. Weinberg, Mary L. Marazita, Jenna C. Carlson, Elizabeth J. Leslie
Published 2021-04-01

Genome-wide association studies in dogs and humans identify ADAMTS20 as a risk variant for cleft lip and palate.

by Zena T Wolf, Harrison A Brand, John R Shaffer, Elizabeth J Leslie, Boaz Arzi, Cali E Willet, Timothy C Cox, Toby McHenry, Nicole Narayan, Eleanor Feingold, Xioajing Wang, Saundra Sliskovic, Nili Karmi, Noa Safra, Carla Sanchez, Frederic W B Deleyiannis, Jeffrey C Murray, Claire M Wade, Mary L Marazita, Danika L Bannasch
Published 2015-03-01

Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate

by Kelsey Robinson, Trenell J. Mosley, Kenneth S. Rivera-González, Christopher R. Jabbarpour, Sarah W. Curtis, Wasiu Lanre Adeyemo, Terri H. Beaty, Azeez Butali, Carmen J. Buxó, David J. Cutler, Michael P. Epstein, Lord J.J. Gowans, Jacqueline T. Hecht, Jeffrey C. Murray, Gary M. Shaw, Lina Moreno Uribe, Seth M. Weinberg, Harrison Brand, Mary L. Marazita, Robert J. Lipinski, Elizabeth J. Leslie
Published 2023-10-01

Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology.

by John R Shaffer, Ekaterina Orlova, Myoung Keun Lee, Elizabeth J Leslie, Zachary D Raffensperger, Carrie L Heike, Michael L Cunningham, Jacqueline T Hecht, Chung How Kau, Nichole L Nidey, Lina M Moreno, George L Wehby, Jeffrey C Murray, Cecelia A Laurie, Cathy C Laurie, Joanne Cole, Tracey Ferrara, Stephanie Santorico, Ophir Klein, Washington Mio, Eleanor Feingold, Benedikt Hallgrimsson, Richard A Spritz, Mary L Marazita, Seth M Weinberg
Published 2016-08-01

Genome-Wide Association Study of Non-syndromic Orofacial Clefts in a Multiethnic Sample of Families and Controls Identifies Novel Regions

by Nandita Mukhopadhyay, Eleanor Feingold, Eleanor Feingold, Eleanor Feingold, Lina Moreno-Uribe, George Wehby, Luz Consuelo Valencia-Ramirez, Claudia P. Restrepo Muñeton, Carmencita Padilla, Frederic Deleyiannis, Kaare Christensen, Fernando A. Poletta, Ieda M. Orioli, Ieda M. Orioli, Jacqueline T. Hecht, Carmen J. Buxó, Azeez Butali, Wasiu L. Adeyemo, Alexandre R. Vieira, John R. Shaffer, John R. Shaffer, Jeffrey C. Murray, Seth M. Weinberg, Seth M. Weinberg, Elizabeth J. Leslie, Mary L. Marazita, Mary L. Marazita, Mary L. Marazita
Published 2021-04-01