A hostel for the hostile: the bone marrow niche in hematologic neoplasms

by Daniela S. Krause, David T. Scadden
Published 2015-11-01

Global transcriptome analysis of T-competent progenitors in the bone marrow

by Vionnie W.C. Yu, David T. Scadden
Published 2015-09-01

Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for label-free detection of molecules across entire cell sections

by Johannes Elferich, Giulia Schiroli, David T Scadden, Nikolaus Grigorieff
Published 2022-11-01

Single Targeted Exon Mutation Creates a True Congenic Mouse for Competitive Hematopoietic Stem Cell Transplantation: The C57BL/6-CD45.1STEM Mouse

by Francois E. Mercier, David B. Sykes, David T. Scadden
Published 2016-06-01

Transcriptome comparison of distinct osteolineage subsets in the hematopoietic stem cell niche using a triple fluorescent transgenic mouse model

by Vionnie W.C. Yu, Stefania Lymperi, Francesca Ferraro, David T. Scadden
Published 2015-09-01

dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments

by Viktor Petukhov, Jimin Guo, Ninib Baryawno, Nicolas Severe, David T. Scadden, Maria G. Samsonova, Peter V. Kharchenko
Published 2018-06-01

SIRT3 Reverses Aging-Associated Degeneration

by Katharine Brown, Stephanie Xie, Xiaolei Qiu, Mary Mohrin, Jiyung Shin, Yufei Liu, Dan Zhang, David T. Scadden, Danica Chen
Published 2013-02-01

Distinctive Mesenchymal-Parenchymal Cell Pairings Govern B Cell Differentiation in the Bone Marrow

by Vionnie W.C. Yu, Stefania Lymperi, Toshihiko Oki, Alexandra Jones, Peter Swiatek, Radovan Vasic, Francesca Ferraro, David T. Scadden
Published 2016-08-01

Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors

by Dongjun Lee, Stephen M. Sykes, Demetrios Kalaitzidis, Andrew A. Lane, Youmna Kfoury, Marc H.G.P. Raaijmakers, Ying-Hua Wang, Scott A. Armstrong, David T. Scadden
Published 2014-11-01

Correction: Tracking Single Cells in Live Animals Using a Photoconvertible Near-Infrared Cell Membrane Label.

by Alicia L. Carlson, Joji Fujisaki, Juwell Wu, Judith M. Runnels, Raphaël Turcotte, Joel A. Spencer, Cristina Lo Celso, David T. Scadden, Terry B. Strom, Charles P. Lin
Published 2013-01-01

Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label.

by Alicia L Carlson, Joji Fujisaki, Juwell Wu, Judith M Runnels, Raphaël Turcotte, Joel A Spencer, Cristina Lo Celso, David T Scadden, Terry B Strom, Charles P Lin
Published 2013-01-01

Cell of origin epigenetic priming determines susceptibility to Tet2 mutation

by Giulia Schiroli, Vinay Kartha, Fabiana M. Duarte, Trine A. Kristiansen, Christina Mayerhofer, Rojesh Shrestha, Andrew Earl, Yan Hu, Tristan Tay, Catherine Rhee, Jason D. Buenrostro, David T. Scadden
Published 2024-05-01

Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning

by Meera A. Srikanthan, Olivier Humbert, Kevin G. Haworth, Christina Ironside, Yogendra S. Rajawat, Bruce R. Blazar, Rahul Palchaudhuri, Anthony E. Boitano, Michael P. Cooke, David T. Scadden, Hans-Peter Kiem
Published 2020-06-01

Immune‐responsive biodegradable scaffolds for enhancing neutrophil regeneration

by Matthew D. Kerr, David A. McBride, Wade T. Johnson, Arun K. Chumber, Alexander J. Najibi, Bo Ri Seo, Alexander G. Stafford, David T. Scadden, David J. Mooney, Nisarg J. Shah
Published 2023-01-01

Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML

by Toshihiko Oki, Francois Mercier, Hiroki Kato, Yookyung Jung, Thomas O. McDonald, Joel A. Spencer, Michael C. Mazzola, Nick van Gastel, Charles P. Lin, Franziska Michor, Toshio Kitamura, David T. Scadden
Published 2021-01-01

Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulation

by Tomoaki Mori, Rakesh Verma, Rie Nakamoto-Matsubara, Ka Tat Siu, Cristina Panaroni, Keertik S. Fulzele, Kenta Mukaihara, Chukwuamaka Onyewadume, Allison Maebius, Hiroki Kato, Lai Ping Wong, Ruslan I. Sadreyev, David T. Scadden, Noopur S. Raje
Published 2021-12-01

Adult Prg4+ progenitors repair long-term articular cartilage wounds in vivo

by Mei Massengale, Justin L. Massengale, Catherine R. Benson, Ninib Barywano, Toshihiko Oki, Matthew L. Steinhauser, Alissa Wang, Deepak Balani, Luke S. Oh, Mark A. Randolph, Thomas J. Gill III, Henry M. Kronenberg, David T. Scadden
Published 2023-09-01

A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma

by Adele M. Alchahin, Shenglin Mei, Ioanna Tsea, Taghreed Hirz, Youmna Kfoury, Douglas Dahl, Chin-Lee Wu, Alexander O. Subtelny, Shulin Wu, David T. Scadden, John H. Shin, Philip J. Saylor, David B. Sykes, Peter V. Kharchenko, Ninib Baryawno
Published 2022-09-01

Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation

by Agnieszka Czechowicz, Rahul Palchaudhuri, Amelia Scheck, Yu Hu, Jonathan Hoggatt, Borja Saez, Wendy W. Pang, Michael K. Mansour, Tiffany A. Tate, Yan Yi Chan, Emily Walck, Gerlinde Wernig, Judith A. Shizuru, Florian Winau, David T. Scadden, Derrick J. Rossi
Published 2019-02-01

Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses

by Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte M. Verhoeven, Alexander O. Subtelny, Dimitar V. Zlatev, Matthew W. Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Z. Macosko, Chin-Lee Wu, David T. Scadden, Douglas M. Dahl, Ninib Baryawno, Philip J. Saylor, Peter V. Kharchenko, David B. Sykes
Published 2023-02-01