Profiles of anemia in adolescent students with sports club membership in an outpatient clinic setting: a retrospective study

by Kana Yamamoto, Morihito Takita, Masahiro Kami, Masaharu Tsubokura, Tetsuya Tanimoto, Toshio Kitamura, Yoshinobu Takemoto
Published 2022-02-01

A simple detection method for low-affinity membrane protein interactions by baculoviral display.

by Toshiko Sakihama, Takato Sato, Hiroko Iwanari, Toshio Kitamura, Shimon Sakaguchi, Tatsuhiko Kodama, Takao Hamakubo
Published 2008-01-01

Robo4 plays a role in bone marrow homing and mobilization, but is not essential in the long-term repopulating capacity of hematopoietic stem cells.

by Yuko Goto-Koshino, Yumi Fukuchi, Fumi Shibata, Daichi Abe, Kana Kuroda, Shinichiro Okamoto, Toshio Kitamura, Hideaki Nakajima
Published 2012-01-01

APC(CDH1) targets MgcRacGAP for destruction in the late M phase.

by Koutarou Nishimura, Toshihiko Oki, Jiro Kitaura, Shinji Kuninaka, Hideyuki Saya, Asako Sakaue-Sawano, Atsushi Miyawaki, Toshio Kitamura
Published 2013-01-01

Spine formation pattern of adult-born neurons is differentially modulated by the induction timing and location of hippocampal plasticity.

by Noriaki Ohkawa, Yoshito Saitoh, Eri Tokunaga, Itsuko Nihonmatsu, Fumiko Ozawa, Akiko Murayama, Fumi Shibata, Toshio Kitamura, Kaoru Inokuchi
Published 2012-01-01

The molecular profiles of neural stem cell niche in the adult subventricular zone.

by Cheol Lee, Jingqiong Hu, Sherry Ralls, Toshio Kitamura, Y Peng Loh, Yanqin Yang, Yoh-suke Mukouyama, Sohyun Ahn
Published 2012-01-01

CRISPR/Cas9-mediated base-editing enables a chain reaction through sequential repair of sgRNA scaffold mutations

by Tsuyoshi Fukushima, Yosuke Tanaka, Keito Adachi, Nanami Masuyama, Akiho Tsuchiya, Shuhei Asada, Soh Ishiguro, Hideto Mori, Motoaki Seki, Nozomu Yachie, Susumu Goyama, Toshio Kitamura
Published 2021-12-01

Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML

by Toshihiko Oki, Francois Mercier, Hiroki Kato, Yookyung Jung, Thomas O. McDonald, Joel A. Spencer, Michael C. Mazzola, Nick van Gastel, Charles P. Lin, Franziska Michor, Toshio Kitamura, David T. Scadden
Published 2021-01-01

Changes in the proportion of anemia among young women after the Great East Japan Earthquake: the Fukushima health management survey

by Kana Yamamoto, Morihito Takita, Masahiro Kami, Yoshinobu Takemoto, Tetsuya Ohira, Masaharu Maeda, Seiji Yasumura, Akira Sakai, Mitsuaki Hosoya, Kanako Okazaki, Hirooki Yabe, Toshio Kitamura, Masaharu Tsubokura, Michio Shimabukuro, Hitoshi Ohto, Kenji Kamiya
Published 2022-06-01

P407: MITOTIC FIDELITY IS A RESISTANCE MECHANISM TO DECITABINE IN MYELOID TUMORS.

by Tomohiro Yabushita, Takumi Chinen, Atsuya Nishiyama, Shuhei Asada, Keita Yamamoto, Naru Sato, Yutaka Enomoto, Keiko Katoh, Kaori Saitoh, Takamasa Ishikawa, Tomoyoshi Soga, Yasuhito Nannya, Makoto Nakanishi, Daiju Kitagawa, Toshio Kitamura, Susumu Goyama
Published 2023-08-01

Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia

by Yasutaka Hayashi, Susumu Goyama, XiaoXiao Liu, Moe Tamura, Shuhei Asada, Yosuke Tanaka, Tomofusa Fukuyama, Mark Wunderlich, Eric O’Brien, Benjamin Mizukawa, Satoshi Yamazaki, Akiko Matsumoto, Satoshi Yamasaki, Tatsuhiro Shibata, Koichi Matsuda, Goro Sashida, Hitoshi Takizawa, Toshio Kitamura
Published 2019-10-01

A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells

by Keita Yamamoto, Susumu Goyama, Shuhei Asada, Takeshi Fujino, Taishi Yonezawa, Naru Sato, Reina Takeda, Akiho Tsuchiya, Tomofusa Fukuyama, Yosuke Tanaka, Akihiko Yokoyama, Hikaru Toya, Ayana Kon, Yasuhito Nannya, Rena Onoguchi-Mizutani, Shinichi Nakagawa, Tetsuro Hirose, Seishi Ogawa, Nobuyoshi Akimitsu, Toshio Kitamura
Published 2021-08-01

Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium

by Tsuyoshi Fukushima, Yosuke Tanaka, Fiona K. Hamey, Chih-Hsiang Chang, Toshihiko Oki, Shuhei Asada, Yasutaka Hayashi, Takeshi Fujino, Taishi Yonezawa, Reina Takeda, Kimihito Cojin Kawabata, Tomofusa Fukuyama, Terumasa Umemoto, Keiyo Takubo, Hitoshi Takizawa, Susumu Goyama, Yasushi Ishihama, Hiroaki Honda, Berthold Göttgens, Toshio Kitamura
Published 2019-12-01

Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis

by Shuhei Asada, Susumu Goyama, Daichi Inoue, Shiori Shikata, Reina Takeda, Tsuyoshi Fukushima, Taishi Yonezawa, Takeshi Fujino, Yasutaka Hayashi, Kimihito Cojin Kawabata, Tomofusa Fukuyama, Yosuke Tanaka, Akihiko Yokoyama, Satoshi Yamazaki, Hiroko Kozuka-Hata, Masaaki Oyama, Shinya Kojima, Masahito Kawazu, Hiroyuki Mano, Toshio Kitamura
Published 2018-07-01

Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors

by Yosuke Tanaka, Reina Takeda, Tsuyoshi Fukushima, Keiko Mikami, Shun Tsuchiya, Moe Tamura, Keito Adachi, Terumasa Umemoto, Shuhei Asada, Naoki Watanabe, Soji Morishita, Misa Imai, Masayoshi Nagata, Marito Araki, Hitoshi Takizawa, Tomofusa Fukuyama, Chrystelle Lamagna, Esteban S. Masuda, Ryoji Ito, Susumu Goyama, Norio Komatsu, Tomoiku Takaku, Toshio Kitamura
Published 2022-01-01

Hyperactive Natural Killer cells in Rag2 knockout mice inhibit the development of acute myeloid leukemia

by Emi Sugimoto, Jingmei Li, Yasutaka Hayashi, Kohei Iida, Shuhei Asada, Tsuyoshi Fukushima, Moe Tamura, Shiori Shikata, Wenyu Zhang, Keita Yamamoto, Kimihito Cojin Kawabata, Tatsuya Kawase, Takeshi Saito, Taku Yoshida, Satoshi Yamazaki, Yuta Kaito, Yoichi Imai, Tamami Denda, Yasunori Ota, Tomofusa Fukuyama, Yosuke Tanaka, Yutaka Enomoto, Toshio Kitamura, Susumu Goyama
Published 2023-12-01

Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway

by Takeshi Fujino, Susumu Goyama, Yuki Sugiura, Daichi Inoue, Shuhei Asada, Satoshi Yamasaki, Akiko Matsumoto, Kiyoshi Yamaguchi, Yumiko Isobe, Akiho Tsuchiya, Shiori Shikata, Naru Sato, Hironobu Morinaga, Tomofusa Fukuyama, Yosuke Tanaka, Tsuyoshi Fukushima, Reina Takeda, Keita Yamamoto, Hiroaki Honda, Emi K. Nishimura, Yoichi Furukawa, Tatsuhiro Shibata, Omar Abdel-Wahab, Makoto Suematsu, Toshio Kitamura
Published 2021-03-01

Disrupting ceramide-CD300f interaction prevents septic peritonitis by stimulating neutrophil recruitment

by Kumi Izawa, Akie Maehara, Masamichi Isobe, Yuka Yasuda, Makoto Urai, Yasutaka Hoshino, Keigo Ueno, Toshihiro Matsukawa, Mariko Takahashi, Ayako Kaitani, Emiko Shiba, Ayako Takamori, Shino Uchida, Koichiro Uchida, Keiko Maeda, Nobuhiro Nakano, Yoshinori Yamanishi, Toshihiko Oki, David Voehringer, Axel Roers, Susumu Nakae, Junko Ishikawa, Yuki Kinjo, Toshiaki Shimizu, Hideoki Ogawa, Ko Okumura, Toshio Kitamura, Jiro Kitaura
Published 2017-06-01

BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state

by Muran Xiao, Shinji Kondo, Masaki Nomura, Shinichiro Kato, Koutarou Nishimura, Weijia Zang, Yifan Zhang, Tomohiro Akashi, Aaron Viny, Tsukasa Shigehiro, Tomokatsu Ikawa, Hiromi Yamazaki, Miki Fukumoto, Atsushi Tanaka, Yasutaka Hayashi, Yui Koike, Yumi Aoyama, Hiromi Ito, Hiroyoshi Nishikawa, Toshio Kitamura, Akinori Kanai, Akihiko Yokoyama, Tohru Fujiwara, Susumu Goyama, Hideki Noguchi, Stanley C. Lee, Atsushi Toyoda, Kunihiko Hinohara, Omar Abdel-Wahab, Daichi Inoue
Published 2023-12-01

IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia

by Xiaoxiao Liu, Naru Sato, Tomohiro Yabushita, Jingmei Li, Yuhan Jia, Moe Tamura, Shuhei Asada, Takeshi Fujino, Tsuyoshi Fukushima, Taishi Yonezawa, Yosuke Tanaka, Tomofusa Fukuyama, Akiho Tsuchiya, Shiori Shikata, Hiroyuki Iwamura, Chieko Kinouchi, Kensuke Komatsu, Satoshi Yamasaki, Tatsuhiro Shibata, Atsuo T Sasaki, Janet Schibler, Mark Wunderlich, Eric O'Brien, Benjamin Mizukawa, James C Mulloy, Yuki Sugiura, Hitoshi Takizawa, Takuma Shibata, Kensuke Miyake, Toshio Kitamura, Susumu Goyama
Published 2023-01-01