Translating DNA into synthetic molecules.

by David R Liu
Published 2004-07-01

Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation

by Weixin Tang, Johnny H. Hu, David R. Liu
Published 2017-06-01

Phage-assisted continuous evolution of proteases with altered substrate specificity

by Michael S. Packer, Holly A. Rees, David R. Liu
Published 2017-10-01

Development of hRad51–Cas9 nickase fusions that mediate HDR without double-stranded breaks

by Holly A. Rees, Wei-Hsi Yeh, David R. Liu
Published 2019-05-01

Disulfide-compatible phage-assisted continuous evolution in the periplasmic space

by Mary S. Morrison, Tina Wang, Aditya Raguram, Colin Hemez, David R. Liu
Published 2021-10-01

Author Correction: Disulfide-compatible phage-assisted continuous evolution in the periplasmic space

by Mary S. Morrison, Tina Wang, Aditya Raguram, Colin Hemez, David R. Liu
Published 2021-11-01

Phage-assisted evolution of highly active cytosine base editors with enhanced selectivity and minimal sequence context preference

by Emily Zhang, Monica E. Neugebauer, Nicholas A. Krasnow, David R. Liu
Published 2024-02-01

An anionic human protein mediates cationic liposome delivery of genome editing proteins into mammalian cells

by Y. Bill Kim, Kevin T. Zhao, David B. Thompson, David R. Liu
Published 2019-07-01

In vivo base editing of post-mitotic sensory cells

by Wei-Hsi Yeh, Hao Chiang, Holly A. Rees, Albert S. B. Edge, David R. Liu
Published 2018-06-01

The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing.

by Yun Huang, William A Pastor, Yinghua Shen, Mamta Tahiliani, David R Liu, Anjana Rao
Published 2010-01-01

Compact zinc finger base editors that edit mitochondrial or nuclear DNA in vitro and in vivo

by Julian C. W. Willis, Pedro Silva-Pinheiro, Lily Widdup, Michal Minczuk, David R. Liu
Published 2022-11-01

Targeting fidelity of adenine and cytosine base editors in mouse embryos

by Hye Kyung Lee, Michaela Willi, Shannon M. Miller, Sojung Kim, Chengyu Liu, David R. Liu, Lothar Hennighausen
Published 2018-11-01

Reciprocal mutations of lung-tropic AAV capsids lead to improved transduction properties

by Ashley L. Cooney, Ashley L. Cooney, Ashley L. Cooney, Christian M. Brommel, Christian M. Brommel, Christian M. Brommel, Soumba Traore, Soumba Traore, Soumba Traore, Gregory A. Newby, Gregory A. Newby, Gregory A. Newby, David R. Liu, David R. Liu, David R. Liu, Paul B. McCray, Paul B. McCray, Paul B. McCray, Patrick L. Sinn, Patrick L. Sinn, Patrick L. Sinn
Published 2023-11-01

Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery

by Holly A. Rees, Alexis C. Komor, Wei-Hsi Yeh, Joana Caetano-Lopes, Matthew Warman, Albert S. B. Edge, David R. Liu
Published 2017-06-01

In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A

by Hyun Ok Ham, Zheng Qu, Carolyn A. Haller, Brent M. Dorr, Erbin Dai, Wookhyun Kim, David R. Liu, Elliot L. Chaikof
Published 2016-04-01

Generating experimentally unrelated target molecule-binding highly functionalized nucleic-acid polymers using machine learning

by Jonathan C. Chen, Jonathan P. Chen, Max W. Shen, Michael Wornow, Minwoo Bae, Wei-Hsi Yeh, Alvin Hsu, David R. Liu
Published 2022-08-01

Inhibition of bacterial conjugation by phage M13 and its protein g3p: quantitative analysis and model.

by Abraham Lin, Jose Jimenez, Julien Derr, Pedro Vera, Michael L Manapat, Kevin M Esvelt, Laura Villanueva, David R Liu, Irene A Chen
Published 2011-01-01

High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases

by Jeffrey L. Bessen, Lena K. Afeyan, Vlado Dančík, Luke W. Koblan, David B. Thompson, Chas Leichner, Paul A. Clemons, David R. Liu
Published 2019-04-01

Addendum: High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases

by Jeffrey L. Bessen, Lena K. Afeyan, Vlado Dančík, Luke W. Koblan, David B. Thompson, Chas Leichner, Paul A. Clemons, David R. Liu
Published 2019-07-01

PrimeDesign software for rapid and simplified design of prime editing guide RNAs

by Jonathan Y. Hsu, Julian Grünewald, Regan Szalay, Justine Shih, Andrew V. Anzalone, Kin Chung Lam, Max W. Shen, Karl Petri, David R. Liu, J. Keith Joung, Luca Pinello
Published 2021-02-01