Regulatory T Cells: Barriers of Immune Infiltration Into the Tumor Microenvironment

by Ellen N. Scott, Ellen N. Scott, Ellen N. Scott, Angela M. Gocher, Angela M. Gocher, Creg J. Workman, Creg J. Workman, Dario A. A. Vignali, Dario A. A. Vignali, Dario A. A. Vignali
Published 2021-06-01

Lymphocyte Activation Gene-3 (LAG-3) negatively regulates environmentally-induced autoimmunity.

by Vibha Jha, Creg J Workman, Tracy L McGaha, Liping Li, Jaya Vas, Dario A A Vignali, Marc Monestier
Published 2014-01-01

Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism

by Tian Du, Li Zhu, Kevin M. Levine, Nilgun Tasdemir, Adrian V. Lee, Dario A. A. Vignali, Bennett Van Houten, George C. Tseng, Steffi Oesterreich
Published 2018-05-01

A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies

by Zhe Sun, Li Chen, Hongyi Xin, Yale Jiang, Qianhui Huang, Anthony R. Cillo, Tracy Tabib, Jay K. Kolls, Tullia C. Bruno, Robert Lafyatis, Dario A. A. Vignali, Kong Chen, Ying Ding, Ming Hu, Wei Chen
Published 2019-04-01

Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP

by Channakeshava Sokke Umeshappa, Patricia Solé, Bas G.J. Surewaard, Jun Yamanouchi, Saswat Mohapatra, Muhammad Myn Uddin, Robert Clarke, Mireia Ortega, Santiswarup Singha, Debajyoti Mondal, Yang Yang, Dario A.A. Vignali, Pau Serra, Paul Kubes, Pere Santamaria
Published 2021-03-01

Treg-Cell-Derived IL-35-Coated Extracellular Vesicles Promote Infectious Tolerance

by Jeremy A. Sullivan, Yusuke Tomita, Ewa Jankowska-Gan, Diego A. Lema, Matt P. Arvedson, Ashita Nair, William Bracamonte-Baran, Ying Zhou, Kristy K. Meyer, Weixiong Zhong, Deepali V. Sawant, Andrea L. Szymczak-Workman, Qianxia Zhang, Creg J. Workman, Seungpyo Hong, Dario A.A. Vignali, William J. Burlingham
Published 2020-01-01

B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma

by Ayana T. Ruffin, Anthony R. Cillo, Tracy Tabib, Angen Liu, Sayali Onkar, Sheryl R. Kunning, Caleb Lampenfeld, Huda I. Atiya, Irina Abecassis, Cornelius H. L. Kürten, Zengbiao Qi, Ryan Soose, Umamaheswar Duvvuri, Seungwon Kim, Steffi Oesterrich, Robert Lafyatis, Lan G. Coffman, Robert L. Ferris, Dario A. A. Vignali, Tullia C. Bruno
Published 2021-06-01

Investigating immune and non-immune cell interactions in head and neck tumors by single-cell RNA sequencing

by Cornelius H. L. Kürten, Aditi Kulkarni, Anthony R. Cillo, Patricia M. Santos, Anna K. Roble, Sayali Onkar, Carly Reeder, Stephan Lang, Xueer Chen, Umamaheswar Duvvuri, Seungwon Kim, Angen Liu, Tracy Tabib, Robert Lafyatis, Jian Feng, Shou-Jiang Gao, Tullia C. Bruno, Dario A. A. Vignali, Xinghua Lu, Riyue Bao, Lazar Vujanovic, Robert L. Ferris
Published 2021-12-01

Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors

by Li Zhu, Jessica L. Narloch, Sayali Onkar, Marion Joy, Gloria Broadwater, Catherine Luedke, Allison Hall, Rim Kim, Katherine Pogue-Geile, Sarah Sammons, Naema Nayyar, Ugonma Chukwueke, Priscilla K. Brastianos, Carey K. Anders, Adam C. Soloff, Dario A. A. Vignali, George C. Tseng, Leisha A. Emens, Peter C. Lucas, Kimberly L. Blackwell, Steffi Oesterreich, Adrian V. Lee
Published 2019-10-01

ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation

by Zheqi Li, Olivia McGinn, Yang Wu, Amir Bahreini, Nolan M. Priedigkeit, Kai Ding, Sayali Onkar, Caleb Lampenfeld, Carol A. Sartorius, Lori Miller, Margaret Rosenzweig, Ofir Cohen, Nikhil Wagle, Jennifer K. Richer, William J. Muller, Laki Buluwela, Simak Ali, Tullia C. Bruno, Dario A. A. Vignali, Yusi Fang, Li Zhu, George C. Tseng, Jason Gertz, Jennifer M. Atkinson, Adrian V. Lee, Steffi Oesterreich
Published 2022-04-01

Lymphocyte‐Activation Gene 3 Facilitates Pathological Tau Neuron‐to‐Neuron Transmission

by Chan Chen, Ramhari Kumbhar, Hu Wang, Xiuli Yang, Kundlik Gadhave, Cyrus Rastegar, Yasuyoshi Kimura, Adam Behensky, Sumasri Kotha, Grace Kuo, Sruthi Katakam, Deok Jeong, Liang Wang, Anthony Wang, Rong Chen, Shu Zhang, Lingtao Jin, Creg J. Workman, Dario A. A. Vignali, Olga Pletinkova, Hongpeng Jia, Weiyi Peng, David W. Nauen, Philip C. Wong, Javier Redding‐Ochoa, Juan C. Troncoso, Mingyao Ying, Valina L. Dawson, Ted M. Dawson, Xiaobo Mao
Published 2024-04-01

Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein

by Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S. Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J. Workman, Dario A. A. Vignali, Ulrike C. Muller, Cong Liu, Han Seok Ko, Valina L. Dawson, Ted M. Dawson
Published 2024-05-01

Combination immunotherapy: Where do we go from here?

by Overacre, Abigail E., Kurtulus, Sema, Sznol, Mario, Pardoll, Drew M., Anderson, Ana, Vignali, Dario A. A.
Published 2015